Abstract: A chromatography column has a column assembly that further includes a column jacket tube and a column liner tube. The column assembly is configured with end fittings that have compression limiting features and are able to withstand very high pressure, such as used in UHPLC, in conjunction with flange portions of the column liner tube that seal the column assembly. The column liner tube may be biocompatible and may have a smooth consistent inner diameter of less than 2 mm, and an inner diameter of 1 mm in particular embodiments. The end fittings for the microtube assembly may ensure durability and reliability by preventing over- or under-tightening.

Abstract: A chromatography column has a column assembly that further includes a column jacket tube and a column liner tube. The column assembly is configured with end fittings that have compression limiting features and are able to withstand very high pressure, such as used in UHPLC, in conjunction with flange portions of the column liner tube that seal the column assembly. The column liner tube may be biocompatible and may have a smooth consistent inner diameter of less than 2 mm, and an inner diameter of 1 mm in particular embodiments. The end fittings for the microtube assembly may ensure durability and reliability by preventing over- or under-tightening.

Abstract: A device which includes a pulse dampener and a degasser or de-bubbler. The device includes a fluid flow path and a fluid chamber located within the device. In addition, the device includes a pulse dampening membrane for dampening pulses in the fluid as it flows through the device. The device also includes a degassing membrane for degassing the fluid as it flows through the device, and/or a de-bubbling membrane for removing gas bubbles from the fluid as it flows through the device. The degassing or de-bubbling membrane can be separate and distinct from the dampening membrane. The de-bubbling membrane can be in addition to or in place of the degassing membrane in some embodiments.

Abstract: A device which includes a pulse dampener and a degasser or de-bubbler. The device includes a fluid flow path and a fluid chamber located within the device. In addition, the device includes a pulse dampening membrane for dampening pulses in the fluid as it flows through the device. The device also includes a degassing membrane for degassing the fluid as it flows through the device, and/or a de-bubbling membrane for removing gas bubbles from the fluid as it flows through the device. The degassing or de-bubbling membrane can be separate and distinct from the dampening membrane. The de-bubbling membrane can be in addition to or in place of the degassing membrane in some embodiments.

Abstract: A device which includes a pulse dampener and a degasser or de-bubbler. The device includes a fluid flow path and a fluid chamber located within the device. In addition, the device includes a pulse dampening membrane for dampening pulses in the fluid as it flows through the device. The device also includes a degassing membrane for degassing the fluid as it flows through the device, and/or a de-bubbling membrane for removing gas bubbles from the fluid as it flows through the device. The degassing or de-bubbling membrane can be separate and distinct from the dampening membrane. The de-bubbling membrane can be in addition to or in place of the degassing membrane in some embodiments.

Abstract: A device which includes a pulse dampener and a degasser or de-bubbler. The device includes a fluid flow path and a fluid chamber located within the device. In addition, the device includes a pulse dampening membrane for dampening pulses in the fluid as it flows through the device. The device also includes a degassing membrane for degassing the fluid as it flows through the device, and/or a de-bubbling membrane for removing gas bubbles from the fluid as it flows through the device. The degassing or de-bubbling membrane can be separate and distinct from the dampening membrane. The de-bubbling membrane can be in addition to or in place of the degassing membrane in some embodiments.