Patents by Inventor David Vincent Butruille
David Vincent Butruille has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11990205Abstract: Exemplary systems and methods for selecting from population of candidate edits and predicting an aggregate effect of the candidate edits are disclosed. One exemplary method includes identifying a population of candidate edits to a genomic sequence of said organism and ranking each of the candidate edits based on a predicted ability of each candidate edit to affect a trait of interest in said organism. The exemplary method further includes selecting one or more of the candidate edits based on the ranking and predicting, by the computing device, an aggregate effect of the selected one or more of the candidate edits for the trait of interest when expressed by a specimen of the organism having a genomic sequence and edited according to the selected one or more of the candidate edits, as compared to an unedited specimen of the organism.Type: GrantFiled: March 29, 2018Date of Patent: May 21, 2024Assignee: Monsanto Technology LLCInventors: David Vincent Butruille, Lex Evan Flagel
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Publication number: 20240110194Abstract: The present disclosure provides novel compositions and methods for collectively transforming or genetically modifying a population of distinct germplasm of different germplasms or having different genotypes. The compositions of the present disclosure may include a population of distinct germplasm, such as embryo explants, and a heterologous polynucleotide molecule, a ribonucleoprotein, or a site-specific nuclease. The methods of the present disclosure may include one or more steps of explant preparation, explant rehydration, Rhizobiales bacterium inoculation and co-culture or particle bombardment, bud induction, extended bud induction, and/or regeneration or development of genetically modified plants or plant parts. The methods provided herein may include transforming at least one plant cell of the embryo explants with a heterologous polynucleotide.Type: ApplicationFiled: October 6, 2023Publication date: April 4, 2024Inventors: Brent Brower-Toland, David Vincent Butruille, Edward J. Cargill, Yurong Chen, Megan Elizabeth Hassebrock, Thomas Ream, Jennifer Rinehart, Mary Ann Saltarikos, Michelle Folta Valentine
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Publication number: 20220361428Abstract: Methods are provided for genome editing. On example method includes editing a genome sequence of an organism with multiple edits simultaneously without precise knowledge of a phenotypic effect of each individual one of the multiple edits, wherein the multiple edits are selected based on a prediction of an aggregate phenotypic effect of the multiple edits on a phenotypic trait. The method also includes aggregating the multiple edits into multi-dimensional pools, whereby phenotypic effects of contrasting pools of edits are compared to ascertain which of the multiple edits are most likely to be causing large phenotypic effects while eliminating need to evaluate each edit separately.Type: ApplicationFiled: July 26, 2022Publication date: November 17, 2022Inventors: David Vincent BUTRUILLE, Lex Evan FLAGEL
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Patent number: 10591467Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: GrantFiled: May 8, 2018Date of Patent: March 17, 2020Assignee: Monsanto Technology LLCInventors: George James Baley, David Vincent Butruille, Vergel C. Concibido, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Publication number: 20180285520Abstract: Exemplary systems and methods for selecting from population of candidate edits and predicting an aggregate effect of the candidate edits are disclosed. One exemplary method includes identifying a population of candidate edits to a genomic sequence of said organism and ranking each of the candidate edits based on a predicted ability of each candidate edit to affect a trait of interest in said organism. The exemplary method further includes selecting one or more of the candidate edits based on the ranking and predicting, by the computing device, an aggregate effect of the selected one or more of the candidate edits for the trait of interest when expressed by a specimen of the organism having a genomic sequence and edited according to the selected one or more of the candidate edits, as compared to an unedited specimen of the organism.Type: ApplicationFiled: March 29, 2018Publication date: October 4, 2018Inventors: David Vincent BUTRUILLE, Lex Evan FLAGEL
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Publication number: 20180259506Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: ApplicationFiled: May 8, 2018Publication date: September 13, 2018Applicant: Monsanto Technology LLCInventors: George James BALEY, David Vincent BUTRUILLE, Vergel C. CONCIBIDO, Samuel R. EATHINGTON, Michael D. HAVERDINK, Warren M. KRUGER, John Robert LeDEAUX, James Narvel, John W. PITKIN, John TAMULONIS, Chongqing XIE
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Patent number: 9995737Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: GrantFiled: June 12, 2015Date of Patent: June 12, 2018Assignee: Monsanto Technologyy LLCInventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Publication number: 20160146792Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: ApplicationFiled: June 12, 2015Publication date: May 26, 2016Applicant: Monsanto Technology LLCInventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Publication number: 20150276721Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: ApplicationFiled: June 12, 2015Publication date: October 1, 2015Applicant: MONSANTO TECHNOLOGY LLCInventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Patent number: 9091681Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: GrantFiled: February 26, 2014Date of Patent: July 28, 2015Assignee: Monsanto Technology LLCInventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Publication number: 20140206032Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: ApplicationFiled: February 26, 2014Publication date: July 24, 2014Applicant: Monsanto Technology LLCInventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Patent number: 8692054Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: GrantFiled: June 21, 2012Date of Patent: April 8, 2014Assignee: Monsanto Technology LLCInventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Publication number: 20140007285Abstract: The present invention relates to the field of plant breeding. More specifically, the present invention includes a method of using haploid plants for genetic mapping of traits of interest such as disease resistance. Further, the invention includes a method for breeding corn plants containing quantitative trait loci (QTL) that are associated with resistance to Gray Leaf Spot, a fungal disease associated with Cercospora spp.Type: ApplicationFiled: August 30, 2013Publication date: January 2, 2014Applicant: MONSANTO TECHNOLOGY LLCInventors: MICHAEL R. KERNS, HONGWU JIA, DAVID VINCENT BUTRUILLE, TRAVIS J. FREY, GILBERTO POZAR, KEVIN COOK, SCOTT WALKER, GREGORY HOLLAND
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Patent number: 8389798Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: GrantFiled: July 8, 2011Date of Patent: March 5, 2013Assignee: Monsanto Technology LLCInventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Publication number: 20120266334Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: ApplicationFiled: June 21, 2012Publication date: October 18, 2012Applicant: MONSANTO TECHNOLOGY LLCInventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Publication number: 20110271409Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: ApplicationFiled: July 8, 2011Publication date: November 3, 2011Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Patent number: 7994395Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: GrantFiled: May 27, 2009Date of Patent: August 9, 2011Assignee: Monsanto Technology LLCInventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Patent number: 7951998Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: GrantFiled: May 24, 2007Date of Patent: May 31, 2011Assignee: Monsanto Technology LLCInventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Publication number: 20090307799Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: ApplicationFiled: May 27, 2009Publication date: December 10, 2009Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
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Publication number: 20080166699Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.Type: ApplicationFiled: May 24, 2007Publication date: July 10, 2008Inventors: George James Baley, David Vincent Butruille, Samuel R. Ethington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie