Patents by Inventor David Vincent Butruille

David Vincent Butruille has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11990205
    Abstract: Exemplary systems and methods for selecting from population of candidate edits and predicting an aggregate effect of the candidate edits are disclosed. One exemplary method includes identifying a population of candidate edits to a genomic sequence of said organism and ranking each of the candidate edits based on a predicted ability of each candidate edit to affect a trait of interest in said organism. The exemplary method further includes selecting one or more of the candidate edits based on the ranking and predicting, by the computing device, an aggregate effect of the selected one or more of the candidate edits for the trait of interest when expressed by a specimen of the organism having a genomic sequence and edited according to the selected one or more of the candidate edits, as compared to an unedited specimen of the organism.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: May 21, 2024
    Assignee: Monsanto Technology LLC
    Inventors: David Vincent Butruille, Lex Evan Flagel
  • Publication number: 20240110194
    Abstract: The present disclosure provides novel compositions and methods for collectively transforming or genetically modifying a population of distinct germplasm of different germplasms or having different genotypes. The compositions of the present disclosure may include a population of distinct germplasm, such as embryo explants, and a heterologous polynucleotide molecule, a ribonucleoprotein, or a site-specific nuclease. The methods of the present disclosure may include one or more steps of explant preparation, explant rehydration, Rhizobiales bacterium inoculation and co-culture or particle bombardment, bud induction, extended bud induction, and/or regeneration or development of genetically modified plants or plant parts. The methods provided herein may include transforming at least one plant cell of the embryo explants with a heterologous polynucleotide.
    Type: Application
    Filed: October 6, 2023
    Publication date: April 4, 2024
    Inventors: Brent Brower-Toland, David Vincent Butruille, Edward J. Cargill, Yurong Chen, Megan Elizabeth Hassebrock, Thomas Ream, Jennifer Rinehart, Mary Ann Saltarikos, Michelle Folta Valentine
  • Publication number: 20220361428
    Abstract: Methods are provided for genome editing. On example method includes editing a genome sequence of an organism with multiple edits simultaneously without precise knowledge of a phenotypic effect of each individual one of the multiple edits, wherein the multiple edits are selected based on a prediction of an aggregate phenotypic effect of the multiple edits on a phenotypic trait. The method also includes aggregating the multiple edits into multi-dimensional pools, whereby phenotypic effects of contrasting pools of edits are compared to ascertain which of the multiple edits are most likely to be causing large phenotypic effects while eliminating need to evaluate each edit separately.
    Type: Application
    Filed: July 26, 2022
    Publication date: November 17, 2022
    Inventors: David Vincent BUTRUILLE, Lex Evan FLAGEL
  • Patent number: 10591467
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: March 17, 2020
    Assignee: Monsanto Technology LLC
    Inventors: George James Baley, David Vincent Butruille, Vergel C. Concibido, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Publication number: 20180285520
    Abstract: Exemplary systems and methods for selecting from population of candidate edits and predicting an aggregate effect of the candidate edits are disclosed. One exemplary method includes identifying a population of candidate edits to a genomic sequence of said organism and ranking each of the candidate edits based on a predicted ability of each candidate edit to affect a trait of interest in said organism. The exemplary method further includes selecting one or more of the candidate edits based on the ranking and predicting, by the computing device, an aggregate effect of the selected one or more of the candidate edits for the trait of interest when expressed by a specimen of the organism having a genomic sequence and edited according to the selected one or more of the candidate edits, as compared to an unedited specimen of the organism.
    Type: Application
    Filed: March 29, 2018
    Publication date: October 4, 2018
    Inventors: David Vincent BUTRUILLE, Lex Evan FLAGEL
  • Publication number: 20180259506
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Application
    Filed: May 8, 2018
    Publication date: September 13, 2018
    Applicant: Monsanto Technology LLC
    Inventors: George James BALEY, David Vincent BUTRUILLE, Vergel C. CONCIBIDO, Samuel R. EATHINGTON, Michael D. HAVERDINK, Warren M. KRUGER, John Robert LeDEAUX, James Narvel, John W. PITKIN, John TAMULONIS, Chongqing XIE
  • Patent number: 9995737
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: June 12, 2018
    Assignee: Monsanto Technologyy LLC
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Publication number: 20160146792
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Application
    Filed: June 12, 2015
    Publication date: May 26, 2016
    Applicant: Monsanto Technology LLC
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Publication number: 20150276721
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Application
    Filed: June 12, 2015
    Publication date: October 1, 2015
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Patent number: 9091681
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Grant
    Filed: February 26, 2014
    Date of Patent: July 28, 2015
    Assignee: Monsanto Technology LLC
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Publication number: 20140206032
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Application
    Filed: February 26, 2014
    Publication date: July 24, 2014
    Applicant: Monsanto Technology LLC
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Patent number: 8692054
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: April 8, 2014
    Assignee: Monsanto Technology LLC
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Publication number: 20140007285
    Abstract: The present invention relates to the field of plant breeding. More specifically, the present invention includes a method of using haploid plants for genetic mapping of traits of interest such as disease resistance. Further, the invention includes a method for breeding corn plants containing quantitative trait loci (QTL) that are associated with resistance to Gray Leaf Spot, a fungal disease associated with Cercospora spp.
    Type: Application
    Filed: August 30, 2013
    Publication date: January 2, 2014
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: MICHAEL R. KERNS, HONGWU JIA, DAVID VINCENT BUTRUILLE, TRAVIS J. FREY, GILBERTO POZAR, KEVIN COOK, SCOTT WALKER, GREGORY HOLLAND
  • Patent number: 8389798
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: March 5, 2013
    Assignee: Monsanto Technology LLC
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Publication number: 20120266334
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Application
    Filed: June 21, 2012
    Publication date: October 18, 2012
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Publication number: 20110271409
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Application
    Filed: July 8, 2011
    Publication date: November 3, 2011
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Patent number: 7994395
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: August 9, 2011
    Assignee: Monsanto Technology LLC
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Patent number: 7951998
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: May 31, 2011
    Assignee: Monsanto Technology LLC
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Publication number: 20090307799
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Application
    Filed: May 27, 2009
    Publication date: December 10, 2009
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Eathington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie
  • Publication number: 20080166699
    Abstract: The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
    Type: Application
    Filed: May 24, 2007
    Publication date: July 10, 2008
    Inventors: George James Baley, David Vincent Butruille, Samuel R. Ethington, Michael D. Haverdink, Warren M. Kruger, John Robert LeDeaux, Vergel C. Concibido, James Narvel, John W. Pitkin, John Tamulonis, Chongqing Xie