Patents by Inventor David W. Sammons
David W. Sammons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9433143Abstract: A drop spreader apparatus generally includes a hopper configured to hold a spreadable material, the container comprises an opening extending linearly across a bottom of the hopper; a wheel and axle assembly comprise two wheels connected by a wheel axle, the wheels and axle configured to support the hopper; a de-bridging and dispensing assembly positioned above the opening of the hopper, the de-bridging and dispensing assembly comprise a de-bridger mechanism configured to sift the spreadable material and a de-bridging driver mechanically coupled to the wheel and axle assembly, the driver configured to drive the de-bridger mechanism using the rotation of the wheels.Type: GrantFiled: October 30, 2014Date of Patent: September 6, 2016Inventors: David W. Sammons, Donald Griffin Bruce
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Publication number: 20150129620Abstract: A drop spreader apparatus generally comprises: a hopper configured to hold a spreadable material, the container comprising an opening extending linearly across a bottom of the hopper; a wheel and axle assembly comprising two wheels connected by a wheel axle, the wheels and axle configured to support the hopper; a de-bridging and dispensing assembly positioned above the opening of the hopper, the de-bridging and dispensing assembly comprising a de-bridger mechanism configured to sift the spreadable material and a de-bridging driver mechanically coupled to the wheel and axle assembly, the driver configured to drive the de-bridger mechanism using the rotation of the wheels.Type: ApplicationFiled: October 30, 2014Publication date: May 14, 2015Inventors: David W. Sammons, Donald Griffin Bruce
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Patent number: 8800752Abstract: A portable feed delivery system can have a first feed container including a first conveyor apparatus that delivers feed to a second feed container, where a second conveyor apparatus delivers feed to a feed delivery conduit that can be directed by a user.Type: GrantFiled: May 17, 2012Date of Patent: August 12, 2014Inventors: David W. Sammons, Donald G. Bruce
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Publication number: 20130305995Abstract: A portable feed delivery system can have a first feed container including a first conveyor apparatus that delivers feed to a second feed container, where a second conveyor apparatus delivers feed to a feed delivery conduit that can be directed by a user.Type: ApplicationFiled: May 17, 2012Publication date: November 21, 2013Inventors: David W. SAMMONS, Donald G. BRUCE
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Patent number: 6210574Abstract: A system for separating nucleated cells from a blood sample includes a charge-flow separator (CFS), which separates blood into fractions according to the surface charge density characteristics coupled with an affinity-filtration separator which either outputs a separated blood fraction to the CFS or receives a separated blood fraction from the CFS. The system permits separation of nucleated fetal red blood cells, erythroid progenitor cells and other nucleated cells found in blood samples.Type: GrantFiled: May 24, 1999Date of Patent: April 3, 2001Assignee: BioSeparations, Inc.Inventors: David W. Sammons, Garland E. Twitty, Joseph G. Utermohlen, Rizwan Sharnez
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Patent number: 6194146Abstract: A method and single solution denaturation and hybridization useful with probes for hybridizing DNA or RNA sequences. The inventive protocol employs a carbinol containing hybridization solution.Type: GrantFiled: October 10, 1997Date of Patent: February 27, 2001Assignee: BioSeparations, Inc.Inventors: Joseph G. Utermohlen, David W. Sammons
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Patent number: 5948617Abstract: A method and single solution denaturation and hybridization solution useful with synthetic oligonucleotide probes for hybridizing DNA or RNA sequences by in situ hybridization. The inventive protocol employs synthetic oligonucleotide probes and a glycerol-based hybridization solution which is particularly useful in fluorescence labeling of chromosomes X, Y, 13, 18 and 21 in human lymphocytes, amniocytes and metaphase chromosomes, with the label being sufficiently stable to permit archival storage of the labeled sample for later hybridization or analysis.Type: GrantFiled: June 13, 1997Date of Patent: September 7, 1999Assignee: BioSpeparations, Inc.Inventors: Joseph G. Utermohlen, David W. Sammons
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Patent number: 5948278Abstract: A method for enriching rare cell populations from a whole blood sample by separating rare cell fractions from whole blood sample according to the relative charge density and/or the relative binding affinity for a leukocyte depletion solid phase matrix is described. The enrichment method may be operated stand alone, or as a pre or post-processing step in conjunction with a charge-flow separation method.Type: GrantFiled: October 10, 1997Date of Patent: September 7, 1999Assignee: BioSeparations, Inc.Inventors: David W. Sammons, Michael Manley, Joseph G. Utermohlen, Garland E. Twitty
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Patent number: 5906724Abstract: A charge-flow separation apparatus (CFS) for enriching rare cell populations, particularly fetal cells, from a whole blood sample by separating the rare cell fractions from whole fractions according to the relative-charge density and/or the relative binding affinity for a leukocyte depletion solid phase matrix is described. The apparatus having an internal cooling system allows for dissipating heat generated by the electric field of the apparatus. The internal cooling system, consisting of a plurality of cooling tubes to circulate coolant material, prevents cellular degradation typically associated with the high heat generated by the electric field and permits the use of a higher voltage gradient to shorten separation times.Type: GrantFiled: July 23, 1997Date of Patent: May 25, 1999Assignee: BioSeparations, Inc.Inventors: David W. Sammons, Garland E. Twitty, Joseph G. Utermohlen, Rizwan Sharnez
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Patent number: 5676849Abstract: A method for enriching rare cell populations from a whole blood sample by separating rare cell fractions from whole according to the relative charge density and/or the relative binding affinity for a leukocyte depletion solid phase matrix. The enrichment method may be operated stand alone, or as a pre or post-processing step in conjunction with a charge-flow separation method.Type: GrantFiled: March 8, 1995Date of Patent: October 14, 1997Assignee: BioSeparations, Inc.Inventors: David W. Sammons, Michael Manley, Joseph G. Utermohlen, Garland E. Twitty
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Patent number: 5662813Abstract: A charge-flow separation apparatus (CFS) and method for enriching rare cell populations, particularly fetal cells, from a whole blood sample by separating the rare cell fractions from whole according to the relative charge density and/or the relative binding affinity for a leukocyte depletion solid phase matrix. The enrichment method may be operated stand alone, or as a pre- or post-processing step in conjunction with a charge-flow separation method.Type: GrantFiled: October 21, 1994Date of Patent: September 2, 1997Assignee: BioSeparations, Inc.Inventors: David W. Sammons, Garland E. Twitty, Joseph G. Utermohlen, Rizwan Sharnez
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Patent number: 5439571Abstract: An apparatus and method of continuous flow zone electrophoresis for separation of particulates or biological samples, including cells and sub-cellular components, in a separation chamber configured to enhance separation of the sample components. The peak-to-peak distance between sample components in a non-equilibrium continuous flow zone electrophoretic fractionator is amplified by selective manipulation of particle residence time within the separation chamber.Type: GrantFiled: November 19, 1991Date of Patent: August 8, 1995Assignee: Bioseparations, Inc.Inventors: David W. Sammons, Rizwan Sharnez
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Patent number: 5336387Abstract: A preparative scale electrical separator, which is matrix-free and may be operated in both a batch mode and a continuous, flow-through mode is provided. It may be scaled according to the solution quantities which are to be processed. An internal cooling system whereby the process fluid is always in close proximity to a chilled surface assures an efficient heat dissipation during the separation and concentration processes and also allows the use of higher voltage gradients and shorter separation times than prior designs of electrophoretic separators. Electroosmotic and convective mixing is reduced by providing internal, compartmentation of sample fractions, focusing is improved and focusing times are decreased. A counter-flow gradient focusing method using the electrophoretic separator allows for separation of cells from human or animal blood and tissues, cells from plants, bacteria and viruses.Type: GrantFiled: November 16, 1992Date of Patent: August 9, 1994Assignee: BioSeparations, Inc.Inventors: Ned B. Egen, Garland E. Twitty, David W. Sammons
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Patent number: 5173164Abstract: A preparative scale multi-mode electrical separator, which is matrix-free and may be operated in both a batch mode and a continuous, flow-through mode is provided. It may be scaled according to the solution quantities which are to be processed. An internal cooling system whereby the process fluid is always in close proximity to a chilled surface assures an efficient heat dissipation during the separation and concentration processes and also allows the use of higher voltage gradients and shorter separation times than prior designs of electrophoretic separators. Electroosmotic mixing is reduced by providing internal, compartmentation of sample fractions, focusing is improved and focusing times are decreased. Different electrophoretic methods, including zone electrophoresis, isoelectric focusing, counterflow gradient focusing or electrodialysis, may be used with the separator. It may be applied to the purification of proteins, ions, and microorganisms, and for water purification.Type: GrantFiled: September 11, 1990Date of Patent: December 22, 1992Assignee: Bioseparations, Inc.Inventors: Ned B. Egen, Garland E. Twitty, David W. Sammons, Rizwan Sharnez
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Patent number: 5073963Abstract: This invention teaches a computerized method for use in data acquisition and manipulation of two-dimensional patterns in the fields of medicine, astronomy, chemistry, biology and biotechnology. The invention teaches an interactive computerized method for matching visual patterns of polypeptide spots in two-dimensional (2-D) gel electrophoretogram solubilized into polypeptide constituents that are separated by electrophoresis. The computerized method manipulates spot pixel coordinates using staged coordinate transformation techniques on spot markers and unknown study spots to reduce gel preparation distortions and allows a user to produce matching results in a manner that compares the transformed spot data using either a single reference gel or multiple reference gels approach for producing the matching results. The method also includes a spot matching verification step and a step to extract potentially mis-matched spots from reported matching results.Type: GrantFiled: May 25, 1990Date of Patent: December 17, 1991Assignee: Arizona Technology Development Corp.Inventors: David W. Sammons, Wen-Jeng Ko, Yi-Cheng Liu
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Patent number: 4434234Abstract: A silver stain procedure wherein a substance capable of binding silver is treated with an aqueous silver salt solution, a reducing solution and an aqueous carbonate or sulfate salt solution and kit useful in practicing same.Type: GrantFiled: June 9, 1982Date of Patent: February 28, 1984Assignee: The Upjohn CompanyInventors: Lonnie D. Adams, David W. Sammons
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Patent number: 4416998Abstract: A silver stain procedure wherein a substance capable of binding silver is treated with a glutaraldehyde solution, an aqueous silver salt solution, a reducing solution and an aqueous carbonate or sulfate solution and kit useful in practicing same.Type: GrantFiled: March 17, 1982Date of Patent: November 22, 1983Assignee: The Upjohn CompanyInventors: Lonnie D. Adams, David W. Sammons