Patents by Inventor David W. Stockton

David W. Stockton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6653082
    Abstract: Assays for analyzing a sample comprising nucleic acid are described, in which the sample is contacted with an array comprising a set of oligonucleotides attached to a solid support at identifiable locations, wherein each oligonucleotide in the set comprises a label at the distal end of the oligonucleotide; incubating the contacted array to allow hybridization of nucleic acid in the sample to the oligonucleotides of the array; subjecting the hybridized array to a cleavage agent which cleaves incompletely hybridized oligonucleotides but does not cleave completely hybridized oligonucleotides; washing the cleaved array; and assessing a pattern of negative and positive signals on the washed, cleaved array, wherein a negative signal corresponds to an incompletely hybridized oligonucleotide that was cleaved by the cleavage agent, thus removing the label, and a positive signal corresponds to an oligonucleotide that was not cleaved by the cleavage agent, thus retaining the label.
    Type: Grant
    Filed: May 16, 2002
    Date of Patent: November 25, 2003
    Assignee: Baylor College of Medicine
    Inventor: David W. Stockton
  • Publication number: 20020187505
    Abstract: Assays for analyzing or genotyping a test sample comprising nucleic acid are described, wherein the assays comprise contacting a prepared test sample containing nucleic acid with an array comprising a set of oligonucleotides attached to a solid support at identifiable locations, wherein each oligonucleotide in the set comprises a first boundary sequence at a proximal end of the oligonucleotide, a second boundary sequence at a distal end of the oligonucleotide, a nucleic acid marker between the first and second boundary sequences, and a label at the distal end of the oligonucleotide; maintaining the contacted array under conditions which allow hybridization of nucleic acid in the test sample to the oligonucleotides of the array; subjecting the hybridized array to a cleavage agent, wherein the cleavage agent cleaves incompletely hybridized oligonucleotides but does not cleave completely hybridized oligonucleotides; washing the cleaved array to remove cleavage products from the cleaved array; and assessing a pat
    Type: Application
    Filed: May 16, 2002
    Publication date: December 12, 2002
    Applicant: Baylor College of Medicine
    Inventor: David W. Stockton
  • Patent number: 5303181
    Abstract: A programmable chip enable provides for enabling or disabling an integrated circuit in response to a selected one of a plurality of logic signals. In a specific application, the programmable enable function is used in combination with a plurality of field programmable memory devices. The enable functions of the respective devices are programmed to prevent simultaneous enablement of the memory devices which have their outputs connected together.
    Type: Grant
    Filed: October 20, 1992
    Date of Patent: April 12, 1994
    Assignee: Harris Corporation
    Inventor: David W. Stockton
  • Patent number: 5179540
    Abstract: A programmable chip enable provides for enabling or disabling an integrated circuit in response to a selected one of a plurality of logic signals. In a specific application, the programmable enable function is used in combination with a plurality of field programmable memory devices. The enable functions of the respective devices are programmed to prevent simultaneous enablement of the memory devices which have their outputs connected together.
    Type: Grant
    Filed: April 25, 1991
    Date of Patent: January 12, 1993
    Assignee: Harris Corporation
    Inventor: David W. Stockton
  • Patent number: 4719598
    Abstract: A programming arrangement for programmable matrices which have a plurality of memory elements, input terminals for addressing the elements, input/output terminals for receiving a signal from an addressed element when the matrix is operated in a READ mode, and for receiving programming signals when the matrix is operated in a PROGRAM mode, and a programming current supply source. The arrangement provides for controlling the flow of programming current to any of the memory elements by application of programming signals to less than all of the input/output terminals. A programming decoder is provided having inputs connected to the input/output terminals and outputs connected to apparatus for controlling the flow of programming current. The decoder expands the programming utility of the input/output terminals and, thus, allows for programming of redundant rows of columns, programmable output polarity apparatus, and other special matrix features via the available device pins.
    Type: Grant
    Filed: May 31, 1985
    Date of Patent: January 12, 1988
    Assignee: Harris Corporation
    Inventor: David W. Stockton