Abstract: A single-load cleaning packet and method of use are provided for laundry and other applications. The cleaning packet in accordance with the present disclosure comprises a paper material that is sealed to form a pouch, and a detergent sealed within the pouch. In embodiments, the paper material is at least partially dissolvable in water to release the detergent included in the pouch. The cleaning packet further comprises a printed message or graphic on the paper material, wherein an ink of the printed message or graphic includes an active ingredient beneficial for wash. In one example, the active ingredient of the ink may include an anti-microbial or anti-odor compound. The incorporation of the active ingredient into the printing ink allows it to be physically separated from the detergent contained within the pouch, thereby aiding in a staggered release during wash.