Abstract: Provided are methods of using human tissue kallikrein-1 (KLK1) to treat chronic kidney disease (CKD) in patients having salt-sensitive hypertension and low KLK1 levels, including methods of identifying and treating optimal sub-populations of CKD patients based on selected genotypes and/or phenotypes.

Abstract: Provided are methods and compositions comprising ulinastatin polypeptides for treating diseases associated with elevated neutrophil elastase (NE), including NE-associated lung and skin diseases.

Abstract: Embodiments of an assembly, including an exercise mat and an absorbent fabric layer, such as a towel, are generally described herein. In one example, an exercise mat is configured for temporary coupling to a towel using corresponding mating components including dual-purpose snap fastener portions respectively affixed to a top surface of the exercise mat and a bottom surface of the towel. The snap fastener portions can be positioned at the corners or sides of the exercise mat and the towel to provide secure usage of the assembly during exercise activity. The exercise mat can include an additional set of mating components including snap fastener portions located on a bottom surface. The additional set of snap fastener portions can be configured to mate with one or more of the snap fastener portions affixed to the top surface of the exercise mat when the exercise mat is oriented into a rolled-up, folded or other compact configuration.