Abstract: The present invention provides for oral care systems comprising: an appliance comprising a first and second plurality of nozzles, the appliance configured to be held in the mouth of a user with the first and second plurality of nozzles in fluid communication with one or more surfaces of the user's oral cavity; a source of gas; a source of liquid; and a fluid controller for directing entrained fluid to the appliance. Also provided are methods of cleaning, or otherwise providing benefits to, one or more surfaces of the oral cavity using a system of the present invention.

Abstract: The present invention provides compositions, methods and kits for treating acne and other skin conditions influenced by P. acnes, which combine administration of low levels of at least one C2 to C5 polycarboxylic acid and blue light to skin in need of treatment for such conditions.

Abstract: Described herein are aqueous oral care compositions comprising (a) an effective amount of a basic amino acid in free or orally acceptable salt form; and (b) a polymer system comprising (i) a cellulosic polymer, (ii) a gum polymer, and (iii) a polyacrylate polymer or co-polymer; and methods of making and using the same.

Abstract: The present invention provides compositions, methods and kits for treating acne and other skin conditions influenced by P. acnes, which combine administration of low levels of at least one C2 to C5 polycarboxylic acid and blue light to skin in need of treatment for such conditions.

Abstract: Disclosed are anti-erosion oral care formulations and methods that provide erosion protection while maintaining adequate cleaning performance. The anti-erosion oral care formulations include a copolymer of a methylvinyl ether and a maleic anhydride and a metal compound or salt that becomes more soluble at acidic pH.

Abstract: The present invention provides compositions, methods and kits for treating acne and other skin conditions influenced by P. acnes, which combine administration of low levels of at least one C2 to C5 polycarboxylic acid and blue light to skin in need of treatment for such conditions.

Abstract: The present invention provides compositions, methods and kits for treating acne and other skin conditions influenced by C. acnes, which combine administration of low levels of at least one substituted resorcinol and blue light to skin in need of treatment for such conditions.

Abstract: The present invention discloses novel uses of specific menthol-derivative compounds of Formula 1, and compositions thereof, for methods of providing oral and systemic health care benefits, and methods of up-regulating or down-regulating periodontal disease metabolites: Formula 1 wherein, X is an oxygen atom or an NH radical; and R is an unsubstituted or substituted aryl or aliphatic radical. In some embodiments, the oral and systemic health care benefits include biofilm anti-attachment, anti-inflammation, anti-oxidant, anti-bone loss, and anti-microbial benefits. In some embodiments, the periodontal disease metabolites correspond to healthy and/or diseased oral status and allow differential diagnosis of oral health.

Abstract: The present invention provides for oral care systems comprising: an appliance comprising a first and second plurality of nozzles, the appliance configured to be held in the mouth of a user with the first and second plurality of nozzles in fluid communication with one or more surfaces of the user's oral cavity; a source of gas; a source of liquid; and a fluid controller for directing entrained fluid to the appliance. Also provided are methods of cleaning, or otherwise providing oral care benefits to, one or more surfaces of the oral cavity using a system of the present invention.

Abstract: The present invention provides for oral care systems comprising: an appliance comprising a first and second plurality of nozzles, the appliance configured to be held in the mouth of a user with the first and second plurality of nozzles in fluid communication with one or more surfaces of the user's oral cavity; a source of gas; a source of liquid; and a fluid controller for directing entrained fluid to the appliance. Also provided are methods of cleaning, or otherwise providing benefits to, one or more surfaces of the oral cavity using a system of the present invention.

Abstract: The present invention provides compositions, methods and kits for treating acne and other skin conditions influenced by P. acnes, which combine administration of low levels of at least one C2 to C5 polycarboxylic acid and blue light to skin in need of treatment for such conditions.

Abstract: Disclosed are oral care compositions and the use of such oral care compositions for treating conditions caused by biofilm formation. Also disclosed are methods for inhibiting biofilm formation and/or degrading biofilm. The oral care composition includes a sesquiterpenoid and an antimicrobial agent, in which the sesquiterpenoid and the antimicrobial agent are present in an amount effective to inhibit and/or degrade a biofilm in the oral cavity.

Abstract: Disclosed are oral care compositions and the use of such oral care compositions for treating conditions caused by biofilm formation. Also disclosed are methods for inhibiting biofilm formation and/or degrading biofilm. The oral care composition includes a sesquiterpenoid and an antimicrobial agent, in which the sesquiterpenoid and the antimicrobial agent are present in an amount effective to inhibit and/or degrade a biofilm in the oral cavity.

Abstract: Disclosed are oral care compositions and the use of such oral care compositions for treating conditions caused by biofilm formation. Also disclosed are methods for inhibiting biofilm formation and/or degrading biofilm. The oral care composition includes a sesquiterpenoid and an antimicrobial agent, in which the sesquiterpenoid and the antimicrobial agent are present in an amount effective to inhibit and/or degrade a biofilm in the oral cavity.

Abstract: Described herein are aqueous oral care compositions comprising (a) an effective amount of a basic amino acid in free or orally acceptable salt form; and (b) a polymer system comprising (i) a cellulosic polymer, (ii) a gum polymer, and (iii) a polyacrylate polymer or co-polymer; and methods of making and using the same.

Abstract: The present invention includes oral care compositions and methods for inhibiting growth and formation of oral biofilms by quorum sensing inhibition and/or bactericidal activity. In some embodiments, the present invention discloses an oral care composition including a therapeutically effective amount of at least one carbonate compound of Formula (1) and at least one excipient: wherein, R1 and R2 are independently: an aliphatic radical; a hydroxyaliphatic radical; or an aryl radical. In some embodiments, the present invention discloses a method of providing oral care benefits including applying to an oral cavity an oral care composition containing a therapeutically effective amount of at least one carbonate compound of Formula (1) and at least one excipient.

Abstract: Disclosed are anti-erosion oral care formulations and methods that provide erosion protection while maintaining adequate cleaning performance. The anti-erosion oral care formulations include a mucoadhesive polymer and a zinc compound or salt that becomes more soluble at acidic pH.

Abstract: Disclosed are anti-erosion oral care formulations and methods that provide erosion protection while maintaining adequate cleaning performance. The anti-erosion oral care formulations include a copolymer of a methylvinyl ether and a maleic anhydride and a metal compound or salt that becomes more soluble at acidic pH.

Abstract: Oral care and other compositions comprising particles having cores attached to bioadhesive polymers for inhibition of pellicle formation, plaque formation, biofilm formation, biofouling, and microbial adhesion or attachment are described. Methods using said compositions to treat surfaces, such as oral surfaces.

Abstract: Disclosed are oral care compositions and the use of such oral care compositions for treating conditions caused by biofilm formation. Also disclosed are methods for inhibiting biofilm formation and/or degrading biofilm. The oral care composition includes a sesquiterpenoid and an antimicrobial agent, in which the sesquiterpenoid and the antimicrobial agent are present in an amount effective to inhibit and/or degrade a biofilm in the oral cavity.