Patents by Inventor Dayton T. Reardan

Dayton T. Reardan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11873272
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Grant
    Filed: January 31, 2023
    Date of Patent: January 16, 2024
    Assignee: Niche Biopharmaceuticals LLC
    Inventors: Dayton T. Reardan, Paul Brennan, Patrick Schlievert
  • Publication number: 20230174473
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Application
    Filed: January 31, 2023
    Publication date: June 8, 2023
    Applicant: Niche Biopharmaceuticals LLC
    Inventors: Dayton T. Reardan, Paul Brennan, Patrick Schlievert
  • Patent number: 11572342
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: February 7, 2023
    Assignee: Niche Biopharmaceuticals LLC
    Inventors: Dayton T. Reardan, Paul Brennan, Patrick Schlievert
  • Patent number: 11365176
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Grant
    Filed: January 6, 2022
    Date of Patent: June 21, 2022
    Assignee: Niche Biopharmaceuticals LLC
    Inventors: Dayton T. Reardan, Paul Brennan, Patrick Schlievert
  • Publication number: 20220127224
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Application
    Filed: January 6, 2022
    Publication date: April 28, 2022
    Inventors: Dayton T. Reardan Ph.D., Paul Brennan, Patrick Schlievert
  • Publication number: 20220089535
    Abstract: The disclosure relates generally novel sulfur containing glycerol mono-ester derivatives and methods useful for treating gram positive, gram negative, fungal and envelope viral infections in a patient.
    Type: Application
    Filed: September 18, 2020
    Publication date: March 24, 2022
    Inventors: Dayton T. Reardan, Paul Brennan, Patrick Schlievert
  • Patent number: 10588947
    Abstract: The invention provides a method for treating a subject who lacks endogenous sucrase activity by orally administering a solution of sacrosidase in about 1:1 glycerol/water having an enzymatic activity of at least about 7500 IU/mL and a residual papain concentration of less than about 10 ng/ml.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: March 17, 2020
    Assignee: QOL Medical LLC
    Inventors: Dayton T. Reardan, Christopher Seekamp
  • Publication number: 20190328882
    Abstract: Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gammahydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorders, including narcolepsy, with these stable formulations of GHB. The present invention also provides methods to treat alcohol and opiate withdrawal, reduced levels of growth hormone, increased intracranial pressure, and physical pain in a patient.
    Type: Application
    Filed: April 12, 2019
    Publication date: October 31, 2019
    Inventors: Harry Cook, Martha Hamilton, Douglas Danielson, Colette Goderstad, Dayton T. Reardan
  • Publication number: 20180193433
    Abstract: One aspect provides an ultrapure, hypoallergenic sacrosidase. Another aspect provides a solution of sacrosidase in about 1:1 glycerol/water having an enzymatic activity of at least about 7500 IU/mL and a residual papain concentration that does not include an allergic reaction in a human patient when given a dose of about 2.0 mL/day.
    Type: Application
    Filed: December 15, 2017
    Publication date: July 12, 2018
    Inventors: Dayton T. Reardan, Christopher Seekamp
  • Patent number: 9849161
    Abstract: One aspect provides an ultrapure, hypoallergenic sacrosidase. Another aspect provides a solution of sacrosidase in about 1:1 glycerol/water having an enzymatic activity of at least about 7500 IU/mL and a residual papain concentration that does not include an allergic reaction in a human patient when given a dose of about 2.0 mL/day.
    Type: Grant
    Filed: September 20, 2016
    Date of Patent: December 26, 2017
    Assignee: QOL Medical LLC
    Inventors: Dayton T. Reardan, Christopher Seekamp
  • Publication number: 20170224825
    Abstract: Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gammahydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorders, including narcolepsy, with these stable formulations of GHB. The present invention also provides methods to treat alcohol and opiate withdrawal, reduced levels of growth hormone, increased intracranial pressure, and physical pain in a patient.
    Type: Application
    Filed: November 18, 2016
    Publication date: August 10, 2017
    Inventors: Harry Cook, Martha Hamilton, Douglas Danielson, Colette Goderstad, Dayton T. Reardan
  • Patent number: 9539330
    Abstract: Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gammahydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorders, including narcolepsy, with these stable formulations of GHB. The present invention also provides methods to treat alcohol and opiate withdrawal, reduced levels of growth hormone, increased intracranial pressure, and physical pain in a patient.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: January 10, 2017
    Assignee: Jazz Pharmaceuticals, Inc.
    Inventors: Harry Cook, Martha Hamilton, Douglas Danielson, Colette Goderstad, Dayton T. Reardan
  • Publication number: 20170000860
    Abstract: One aspect provides an ultrapure, hypoallergenic sacrosidase. Another aspect provides a solution of sacrosidase in about 1:1 glycerol/water having an enzymatic activity of at least about 7500 IU/mL and a residual papain concentration that does not include an allergic reaction in a human patient when given a dose of about 2.0 mL/day.
    Type: Application
    Filed: September 20, 2016
    Publication date: January 5, 2017
    Inventors: Dayton T. Reardan, Christopher Seekamp
  • Patent number: 9469847
    Abstract: One aspect provides an ultrapure, hypoallergenic sacrosidase. Another aspect provides a solution of sacrosidase in about 1:1 glycerol/water having an enzymatic activity of at least about 7500 IU/mL and a residual papain concentration that does not include an allergic reaction in a human patient when given a dose of about 2.0 mL/day.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: October 18, 2016
    Assignee: QOL Medical LLC
    Inventors: Dayton T. Reardan, Christopher Seekamp
  • Publication number: 20160180058
    Abstract: A drug distribution system and method utilizes a central pharmacy and database to track all prescriptions for a sensitive drug. Information is kept in the database regarding all physicians allowed to prescribe the sensitive drug, and all patients receiving the drug. Abuses are identified by monitoring data in the database for prescription patterns by physicians and prescriptions obtained by patients. Further verification is made that the physician is eligible to prescribe the drug by consulting a separate database, and optionally whether any actions are taken against the physician. Multiple controls beyond those for normal drugs are imposed on the distribution depending on the sensitivity of the drug.
    Type: Application
    Filed: March 1, 2016
    Publication date: June 23, 2016
    Inventors: Dayton T. Reardan, Patti A. Engel, Bob Gagne
  • Publication number: 20160154947
    Abstract: A drug distribution system and method utilizes a central pharmacy and database to track all prescriptions for a sensitive drug. Information is kept in the database regarding all physicians allowed to prescribe the sensitive drug, and all patients receiving the drug. Abuses are identified by monitoring data in the database for prescription patterns by physicians and prescriptions obtained by patients. Further verification is made that the physician is eligible to prescribe the drug by consulting a separate database, and optionally whether any actions are taken against the physician. Multiple controls beyond those for normal drugs are imposed on the distribution depending on the sensitivity of the drug.
    Type: Application
    Filed: February 3, 2016
    Publication date: June 2, 2016
    Inventors: Dayton T. Reardan, Patti A. Engel, Bob Gagne
  • Publication number: 20160058862
    Abstract: Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gammahydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorders, including narcolepsy, with these stable formulations of GHB. The present invention also provides methods to treat alcohol and opiate withdrawal, reduced levels of growth hormone, increased intracranial pressure, and physical pain in a patient.
    Type: Application
    Filed: November 9, 2015
    Publication date: March 3, 2016
    Inventors: Harry Cook, Martha Hamilton, Douglas Danielson, Colette Goderstad, Dayton T. Reardan
  • Patent number: 9255261
    Abstract: One aspect provides an ultrapure, hypoallergenic sacrosidase. Another aspect provides a solution of sacrosidase in about 1:1 glycerol/water having an enzymatic activity of at least about 7500 IU/mL and a residual papain concentration that does not include an allergic reaction in a human patient when given a dose of about 2.0 mL/day.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: February 9, 2016
    Assignee: QOL Medical LLC
    Inventors: Dayton T. Reardan, Christopher Seekamp
  • Publication number: 20150343032
    Abstract: One aspect provides an ultrapure, hypoallergenic sacrosidase. Another aspect provides a solution of sacrosidase in about 1:1 glycerol/water having an enzymatic activity of at least about 7500 IU/mL and a residual papain concentration that does not include an allergic reaction in a human patient when given a dose of about 2.0 mL/day.
    Type: Application
    Filed: August 17, 2015
    Publication date: December 3, 2015
    Inventors: Dayton T. Reardan, Christopher Seekamp
  • Publication number: 20150225707
    Abstract: One aspect provides an ultrapure, hypoallergenic sacrosidase. Another aspect provides a solution of sacrosidase in about 1:1 glycerol/water having an enzymatic activity of at least about 7500 IU/mL and a residual papain concentration that does not include an allergic reaction in a human patient when given a dose of about 2.0 mL/day.
    Type: Application
    Filed: February 7, 2014
    Publication date: August 13, 2015
    Applicant: QOL Medical LLC
    Inventors: Dayton T. Reardan, Christopher Seekamp