Patents by Inventor Dean A. Handley

Dean A. Handley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150196531
    Abstract: Provided herein are methods of treating a sleep-related breathing disorder, such as obstructive sleep apnea, comprising the administration of O-desmethylvenlafaxine or duloxetine.
    Type: Application
    Filed: March 27, 2015
    Publication date: July 16, 2015
    Inventors: Dean A. Handley, Larry W. Hardy, Merdad Vaziri Parsey
  • Publication number: 20120238616
    Abstract: Provided herein are methods of treating a sleep-related breathing disorder, such as obstructive sleep apnea, comprising the administration of O-desmethylvenlafaxine or duloxetine.
    Type: Application
    Filed: May 25, 2012
    Publication date: September 20, 2012
    Inventors: Dean A. Handley, Larry W. Hardy, Merdad Vaziri Parsey
  • Publication number: 20080293823
    Abstract: Provided herein are methods of treating a sleep-related breathing disorder, such as obstructive sleep apnea, comprising the administration of O-desmethylvenlafaxine or duloxetine.
    Type: Application
    Filed: April 9, 2008
    Publication date: November 27, 2008
    Inventors: Dean A. Handley, Larry W. Hardy, Merdad Vaziri Parsey
  • Publication number: 20030109540
    Abstract: Methods utilizing descarboethoxyloratadine (“DCL”) for the treatment of allergic disorders, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. Also included are methods for the treatment of allergic asthma using DCL and either a decongestant or a leukotriene inhibitor, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. The invention also encompasses the administration of DCL in a nasal or oral spray.
    Type: Application
    Filed: October 15, 2002
    Publication date: June 12, 2003
    Applicant: Sepracor Inc.
    Inventors: Dean A. Handley, Paul D. Rubin
  • Patent number: 6498171
    Abstract: Methods and compositions are disclosed utilizing hydroxyomeprazole for the treatment of ulcers in humans. Hydroxyomeprazole exhibits a lessened liability toward drug-drug interactions than omeprazole and a more predictable dosing regimen than omeprazole. Hydroxyomeprazole is also useful for the treatment of gastroesophageal reflux and other conditions related to gastric hypersecretion such as Zollinger-Ellison Syndrome.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: December 24, 2002
    Assignee: Sepracor Inc.
    Inventors: William E. Yelle, Dean A. Handley
  • Publication number: 20020151543
    Abstract: Pharmaceutical compositions which comprises R(−) fluoxetine and one or more other biologically active compounds are disclosed. Methods of treating or preventing a disease or disorder, especially a psychotic or psychiatric disease or disorder, using the above pharmaceutical composition or by administering a R(−) fluoxetine in combination with one or more other biologically active compounds are also disclosed. Methods of treating patients having or at risk of having AIDS or HIV infection, cancer, cardiac disorder, post-myocardial depression and posttraumatic stress disorder using optically pure R(−) fluoxetine in combination with one or more other biologically active compounds are further disclosed.
    Type: Application
    Filed: June 3, 2002
    Publication date: October 17, 2002
    Applicant: Sepracor Inc.
    Inventors: Timothy J. Barberich, Paul D. Rubin, Dean A. Handley
  • Publication number: 20020040034
    Abstract: Methods utilizing descarboethoxyloratadine (“DCL”), for the treatment of allergic disorders, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. Also included are methods for the treatment of allergic asthma using DCL and either a decongestant or a leukotriene inhibitor, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. The invention also encompasses the administration of DCL in a nasal or oral spray.
    Type: Application
    Filed: April 24, 2000
    Publication date: April 4, 2002
    Inventors: Dean A. Handley, Paul D. Rubin
  • Publication number: 20020010196
    Abstract: Methods and compositions are disclosed utilizing hydroxyomeprazole for the treatment of ulcers in humans. Hydroxyomeprazole exhibits a lessened liability toward drug-drug interactions than omeprazole and a more predictable dosing regimen than omeprazole. Hydroxyomeprazole is also useful for the treatment of gastroesophageal reflux and other conditions related to gastric hypersecretion such as Zollinger-Ellison Syndrome.
    Type: Application
    Filed: August 10, 2001
    Publication date: January 24, 2002
    Inventors: William E. Yelle, Dean A. Handley
  • Patent number: 6294586
    Abstract: Methods and compositions are disclosed utilizing hydroxyomeprazole for the treatment of ulcers in humans. Hydroxyomeprazole exhibits a lessened liability toward drug-drug interactions than omeprazole and a more predictable dosing regimen than omeprazole. Hydroxyomeprazole is also useful for the treatment of gastroesophageal reflux and other conditions related to gastric hypersecretion such as Zollinger-Ellison Syndrome.
    Type: Grant
    Filed: October 30, 2000
    Date of Patent: September 25, 2001
    Assignee: Sepracor Inc.
    Inventors: William E. Yelle, Dean A. Handley
  • Patent number: 6054463
    Abstract: The invention relates to methods of utilizing descarboethoxyloratadine ("DCL") for the treatment of dermatitis. The invention also encompasses the topical administration of descarboethoxyloratadine using various dosage forms for the treatment of dermatitis.
    Type: Grant
    Filed: March 17, 1999
    Date of Patent: April 25, 2000
    Assignee: Sepracor Inc.
    Inventors: Dean A. Handley, Paul D. Rubin
  • Patent number: 5962464
    Abstract: Methods utilizing descarboethoxyloratadine ("DCL"), for the treatment of allergic disorders, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. Also included are methods for the treatment of allergic asthma using DCL and either a decongestant or a leukotriene inhibitor, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. The invention also encompasses the administration of DCL in a nasal or oral spray.
    Type: Grant
    Filed: July 6, 1998
    Date of Patent: October 5, 1999
    Assignee: Sepracor Inc.
    Inventors: Dean A. Handley, Paul D. Rubin
  • Patent number: 5900421
    Abstract: Methods utilizing descarboethoxyloratadine ("DCL"), for the treatment of allergic disorders, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. Also included are methods for the treatment of allergic asthma using DCL and either a decongestant or a leukotriene inhibitor, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. The invention also encompasses the administration of DCL in a nasal or oral spray.
    Type: Grant
    Filed: February 11, 1997
    Date of Patent: May 4, 1999
    Assignee: Sepracor Inc.
    Inventors: Dean A. Handley, Paul D. Rubin
  • Patent number: 5409894
    Abstract: Somatostatin analogues and derivatives in free form or in pharmaceutically acceptable salt or complex form are useful for preventing or reducing neointimal proleferation following angioplasty.
    Type: Grant
    Filed: July 6, 1993
    Date of Patent: April 25, 1995
    Assignee: Sandoz Ltd.
    Inventor: Dean A. Handley
  • Patent number: 5177059
    Abstract: Polymyxin B carrier conjugates, especially polymyxin B-dextran, are water soluble, have a greater half-life in the bloodstream and are significantly less toxic than native polymyxin B.
    Type: Grant
    Filed: November 1, 1990
    Date of Patent: January 5, 1993
    Assignee: Sandoz Ltd.
    Inventors: Dean A. Handley, Philip Lake
  • Patent number: 5010067
    Abstract: An injectable pharmaceutical mixture comprises:(A) a water-oil emulsion vehicle comprising:(a) about 5 to 25% fatty acid triglycerides;(b) sufficient physiologically acceptable emulsifying agent, e.g. from about 0 to 1.2% egg phosphatides, purified; andthe balance water, with sufficient alkali metal hydroxide added to adjust to an alkaline pH: and(B) an active ingredient which is a PAF receptor inhibitor or anti-tumor agent, which is an ether or carbamoyl phospholipid salt.
    Type: Grant
    Filed: July 19, 1988
    Date of Patent: April 23, 1991
    Assignee: Sandoz Pharmaceuticals Corp.
    Inventors: Dean A. Handley, William J. Houlihan, David B. Weinstein