Patents by Inventor Dean A. Kirby

Dean A. Kirby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRFR2 selective ligands
    Patent number: 7141546
    Abstract: CRF peptide analogs that bind to CRFR2 with an affinity far greater than they bind to CRFR1. These analogs exhibit CRF antagonist activity, and they can be based upon the native structures of sauvagine, CRF, and urocortin.
    Type: Grant
    Filed: July 31, 2002
    Date of Patent: November 28, 2006
    Assignee: The Salk Institute for Biologicial Studies
    Inventors: Jean E. F. Rivier, Wylie W. Vale, Marilyn H. Perrin, Jozsef Gulyas, Dean A. Kirby
  • Centrally truncated NPY cyclic peptides
    Patent number: 5569742
    Abstract: Centrally truncated NPY cyclic peptide analogs are described which have selective bioactivity for NPY Y1 receptors. Methods are provided for diagnosing physiological disorders manifested by abnormal levels of endogenous Y1 receptors, by means of measuring the amount of a NPY Y1 specific cyclic peptide analog which binds to a biological sample, and by means of administering a radiolabelled NPY Y1 specific cyclic peptide analog to a host subject followed by radiographic imaging. A method is further provided for therapeutic use of the cyclic peptide NPY analogs in clinical treatment of hypotension and anorexia.
    Type: Grant
    Filed: June 22, 1994
    Date of Patent: October 29, 1996
    Assignee: The Salk Institute for Biological Studies
    Inventors: Dean A. Kirby, Jean E. F. Rivier