Abstract: Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.

Abstract: The present invention includes pressure event indicators that identify specific pressurized vessels or pipes from which a pressurized fluid has been exhausted, closed pressurized systems that implement such pressure event indicators, and methods of using such pressure event indicators. Embodiments of such pressure event indicators may include a housing having a substantially horizontal elongate passage, a rotatable axle orthogonally passing through the passage, a paddle fixedly attached to the axle having a closed position, an open position, and a shape that is complementary to a portion of the passage and that occludes a portion of the passage when the paddle is in the closed position, and at least one visual indicator outside of the housing and fixedly attached to the axle, where the purpose of the visual indicator is to identify a position of the paddle to an observer.

Abstract: A portable computer with a touch sensitive screen includes computer aided design (CAD) software that complements CAD software on a main computer. Drawings from the main computer can be downloaded onto the portable computer, modified remotely, and then uploaded back to the main computer to reflect the drawing changes. In one embodiment, the device records data only when the user lifts a stylus from a touch sensitive screen, allowing the device to be used in physically unstable environments.