Abstract: A method of screening, diagnosing, or treating an NF-&kgr;B induced pathology through the use of NF-&kgr;B modulating agents. These cells isolated from pathological regions of a subject can be cultured in the presence or absence of a modulating agent to detect a change in proliferation of the cells, wherein a change in proliferation in modulator treated cells compared to control cells shows that the cells are derived from an NF-&kgr;B induced pathology. A subject that contains cells derived from an NF-&kgr;B induced pathology can be diagnosed with this pathology. NF-&kgr;B modulators can then be used to treat the NF-&kgr;B induced pathology.

Abstract: This invention relates to a method of combatting cancer which cancer releases chorionic gonadotropin or a subunit thereof present in a mammal which method comprises administering to said animal an anti-cancer effective amount of a birth-control vaccine or an antibody to said chorionic gonadotropin or subunit thereof. Birth-control vaccines which are polyvalent vaccines and birth-control vaccines which employ recombinant organisms incorporating sequences coding for reproductive hormones are of particular interest as well as polyclonal and monoclonal antibodies to the chorionic gonadotropin.

Abstract: The present invention includes, inter alia, methods of treating cells infected with a virus capable of causing an immunodeficiency disease and related pharmaceutical compositions.

Abstract: Hybrid DNA capable of effecting controlled amplification in a host cell of a heterologous gene that determines a specific function. The hybrid DNA has the following three different regions of DNA: (1) an "amplicon" that is inducible by an external stimulus; (2) the heterologous gene (or a site for its insertion); and (3) a selectable marker enabling isolation of the transformed host cells. In order to make a desired compound coded by the heterologous gene, a vehicle including the hybrid DNA is introduced into a host cell is transformed with the vector, transformed host cells are grown to a desired population, the external stimulus is controlled to effect amplification of the gene in members of the population, cells containing amplified gene are cultured, and the compound is recovered.