Patents by Inventor Debra Wallace

Debra Wallace has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biologically active peptides and compositions, their use
    Patent number: 7772397
    Abstract: This invention relates to derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by general formula I, wherein Y, n, R1, R2, R3, R6, R7, R70, R71, R72, R74, and R75 are as defined in the specification.
    Type: Grant
    Filed: July 21, 2008
    Date of Patent: August 10, 2010
    Assignee: University of British Columbia
    Inventors: Raymond Andersen, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michel Roberge, Theresa Allen
  • PROCESS FOR MAKING LACTAM TACHYKININ RECEPTOR ANTAGONISTS
    Publication number: 20090247770
    Abstract: The present invention is directed to a process for preparing ?,? disubstituted ?-lactam derivatives of formula (I) that are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The compounds are useful in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.
    Type: Application
    Filed: August 3, 2007
    Publication date: October 1, 2009
    Inventors: Kevin R. Campos, Cheng Chen, Hideaki Ishibashi, Shinji Kato, Artis Klapars, Yoshinori Kohmura, David J. Pollard, Akihiro Takezawa, Jacob H. Waldman, Debra Wallace, Nobuyoshi Yasuda
  • BIOLOGICALLY ACTIVE PEPTIDES AND COMPOSITIONS, THEIR USE
    Publication number: 20090088573
    Abstract: This invention relates to derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by general formula I, wherein Y, n, R1, R2, R3, R6, R7, R70, R71, R72, R74, and R75 are as defined in the specification.
    Type: Application
    Filed: July 21, 2008
    Publication date: April 2, 2009
    Applicant: The University of British Columbia
    Inventors: Raymond ANDERSEN, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michel Roberge, Theresa Allen
  • Biologically active peptides and compositions, their use
    Patent number: 7410951
    Abstract: Derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by formula I wherein Y, n, R1, R2, R3, R7, R70, R71, R72, R74, and R75 are as defined in the specification.
    Type: Grant
    Filed: January 14, 2005
    Date of Patent: August 12, 2008
    Assignee: The University of British Columbia
    Inventors: Raymond Andersen, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michel Roberge, Theresa Allen
  • Biologically active peptides and compositions, their use
    Publication number: 20050171137
    Abstract: This invention relates to derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by general formula I, wherein Y, n, R1, R2, R3, R6, R7, R70, R71, R72, R74, and R75 are as defined in the specification.
    Type: Application
    Filed: January 14, 2005
    Publication date: August 4, 2005
    Inventors: Raymond Andersen, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michael Roberge, Teresa Allen
  • Biologically active peptides and compositions, their use
    Patent number: 6870028
    Abstract: This invention relates to derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by general formula I, wherein Y, n, R1, R2, R3, R6, R7, R70, R71, R72, R74, and R75 are as defined in the specification.
    Type: Grant
    Filed: June 14, 2000
    Date of Patent: March 22, 2005
    Assignees: University of British Columbia, University of Alberta
    Inventors: Raymond Andersen, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michael Roberge, Theresa Allen
  • Biologically active peptides and compositions, their use
    Patent number: 6153590
    Abstract: Compounds of general formula I ##STR1## wherein: R.sub.1 and R.sub.70 independently represent a hydrogen atom or an optionally substituted alkyl or acyl group; R.sub.2 represents a hydrogen atom or an optionally substituted alkyl or acyl group or is absent when R.sub.6 represents a group --CH.dbd. as hereinafter described; R.sub.73 represents a hydrogen atom or an optional substituent or is absent when R.sub.6 represents a methylene group or a group --CH.dbd. as hereinafter described; Y represents an optional substituent; n represents 0, 1, 2, 3, or 4; R.sub.3 represents a hydrogen atom, or an optionally substituted alkyl group; R.sub.74 represents a hydrogen atom, a hydroxy group or an optionally substituted alkyl or acyl group; R.sub.7 represents a hydrogen atom or an alkyl group; R.sub.75 represents an optionally substituted alkyl group; and i) R.sub.6 and R.sub.71 independently represent a hydrogen atom or an optionally substituted alkyl or acyl group; and R.sub.72 represents a hydrogen atom; or ii) R.
    Type: Grant
    Filed: February 2, 1998
    Date of Patent: November 28, 2000
    Assignees: University of Alberta, University of British Columbia
    Inventors: Raymond Andersen, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michel Roberge, Teresa Allen