Patents by Inventor Dejan Knezevic

Dejan Knezevic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to Use Gene Expression to Determine Likelihood of Clinical Outcome of Renal Cancer
    Publication number: 20240096451
    Abstract: The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
    Type: Application
    Filed: August 23, 2023
    Publication date: March 21, 2024
    Applicant: Genomic Health, Inc.
    Inventors: Wayne Cowens, Steven SHAK, Audrey GODDARD, Dejan KNEZEVIC, Joffre Baker, Michael C. Kiefer, Tara MADDALA, Frederick L. Baehner
  • DNA Methylation and Mutational Analysis Methods for Bladder Cancer Surveillance
    Publication number: 20230374604
    Abstract: The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations. In some embodiments, analysis results are correlated with clinical outcome measures such as risk of bladder cancer recurrence.
    Type: Application
    Filed: April 4, 2023
    Publication date: November 23, 2023
    Applicant: Genomic Health, Inc.
    Inventors: Margarita LOPATIN, Athanasios TSIATIS, Christopher N. SILK, David P. MILLER, Michael R. CRAGER, Phillip FEBBO, Dejan KNEZEVIC
  • Method to use gene expression to determine likelihood of clinical outcome of renal cancer
    Patent number: 11776664
    Abstract: The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: October 3, 2023
    Assignee: Genomic Health, Inc.
    Inventors: Wayne Cowens, Steven Shak, Audrey Goddard, Dejan Knezevic, Joffre Baker, Michael C. Kiefer, Tara Maddala, Frederick L. Baehner
  • DNA methylation and mutational analysis methods for bladder cancer surveillance
    Patent number: 11649506
    Abstract: The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations. In some embodiments, analysis results are correlated with clinical outcome measures such as risk of bladder cancer recurrence.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: May 16, 2023
    Assignee: Genomic Health, Inc.
    Inventors: Margarita Lopatin, Athanasios Tsiatis, Christopher N. Silk, David P. Miller, Michael Crager, Phillip Febbo, Dejan Knezevic
  • Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer
    Patent number: 11551782
    Abstract: The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The present invention also provides methods of obtaining a quantitative score for a patient with kidney cancer based on measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The genes may be grouped into functional gene subsets for calculating the quantitative score and the gene subsets may be weighted according to their contribution to cancer recurrence.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: January 10, 2023
    Assignee: Genomic Health, Inc.
    Inventors: Steven Shak, George Andrew Watson, Michael R. Crager, Tara Maddala, Margarita Lopatin, Audrey Goddard, Dejan Knezevic, Christer Svedman
  • Method to Use Gene Expression to Determine Likelihood of Clinical Outcome of Renal Cancer
    Publication number: 20220051755
    Abstract: The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
    Type: Application
    Filed: November 19, 2020
    Publication date: February 17, 2022
    Applicant: Genomic Health, Inc.
    Inventors: Wayne COWENS, Steven SHAK, Audrey GODDARD, Dejan KNEZEVIC, Joffre BAKER, Michael C. KIEFER, Tara MADDALA, Frederick L. BAEHNER
  • Gene Expression Profile Algorithm for Calculating a Recurrence Score for a Patient with Kidney Cancer
    Publication number: 20220044760
    Abstract: The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The present invention also provides methods of obtaining a quantitative score for a patient with kidney cancer based on measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The genes may be grouped into functional gene subsets for calculating the quantitative score and the gene subsets may be weighted according to their contribution to cancer recurrence.
    Type: Application
    Filed: November 2, 2020
    Publication date: February 10, 2022
    Applicant: Genomic Health, Inc.
    Inventors: Steven SHAK, George Andrew WATSON, Michael R. CRAGER, Tara MADDALA, Margarita LOPATIN, Audrey GODDARD, Dejan KNEZEVIC, Christer SVEDMAN
  • Method to Use Gene Expression to Determine Likelihood of Clinical Outcome of Renal Cancer
    Publication number: 20210166790
    Abstract: The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
    Type: Application
    Filed: November 19, 2020
    Publication date: June 3, 2021
    Applicant: Genomic Health, Inc.
    Inventors: Wayne COWENS, Steven SHAK, Audrey GODDARD, Dejan KNEZEVIC, Joffre BAKER, Michael C. KIEFER, Tara MADDALA, Frederick L. BAEHNER
  • Gene Expression Profile Algorithm for Calculating a Recurrence Score for a Patient with Kidney Cancer
    Publication number: 20210151122
    Abstract: The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The present invention also provides methods of obtaining a quantitative score for a patient with kidney cancer based on measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The genes may be grouped into functional gene subsets for calculating the quantitative score and the gene subsets may be weighted according to their contribution to cancer recurrence.
    Type: Application
    Filed: November 2, 2020
    Publication date: May 20, 2021
    Applicant: Genomic Health, Inc.
    Inventors: Steven SHAK, George Andrew WATSON, Michael R. CRAGER, Tara MADDALA, Margarita LOPATIN, Audrey GODDARD, Dejan KNEZEVIC, Christer SVEDMAN
  • Gene expression profile algorithm and test for determining prognosis of prostate cancer
    Patent number: 11011252
    Abstract: The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes, or their co-expressed genes, from a biological sample obtained from a prostate cancer patient. The genes may be grouped into functional gene subsets for calculating a quantitative score useful to predict a likelihood of a clinical outcome for a prostate cancer patient.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: May 18, 2021
    Assignee: Genomic Health, Inc.
    Inventors: Steven Shak, Mark Lee, William F. Novotny, Tara Maddala, Michael R. Crager, Diana Cherbavaz, Robert J. Pelham, Carl L. Millward, Dejan Knezevic
  • Method to use gene expression to determine likelihood of clinical outcome of renal cancer
    Patent number: 10892038
    Abstract: The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: January 12, 2021
    Assignee: Genomic Health, Inc.
    Inventors: Wayne Cowens, Steven Shak, Audrey Goddard, Dejan Knezevic, Joffre Baker, Michael C. Kiefer, Tara Maddala, Frederick L. Baehner
  • DNA Methylation and Mutational Analysis Methods for Bladder Cancer Surveillance
    Publication number: 20200165686
    Abstract: The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations. In some embodiments, analysis results are correlated with clinical outcome measures such as risk of bladder cancer recurrence.
    Type: Application
    Filed: May 17, 2018
    Publication date: May 28, 2020
    Applicant: Genomic Health, Inc.
    Inventors: Margarita LOPATIN, Athanasios TSIATIS, Christopher N. SILK, David P. Miller, Michael CRAGER, Phillip FEBBO, Dejan KNEZEVIC
  • Gene Expression Profile Algorithm for Calculating a Recurrence Score for a Patient with Kidney Cancer
    Publication number: 20190095575
    Abstract: The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The present invention also provides methods of obtaining a quantitative score for a patient with kidney cancer based on measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The genes may be grouped into functional gene subsets for calculating the quantitative score and the gene subsets may be weighted according to their contribution to cancer recurrence.
    Type: Application
    Filed: November 26, 2018
    Publication date: March 28, 2019
    Applicant: Genomic Health, Inc.
    Inventors: Steven SHAK, George Andrew WATSON, Michael R. CRAGER, Tara MADDALA, Margarita LOPATIN, Audrey GODDARD, Dejan KNEZEVIC, Christer SVEDMAN
  • Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer
    Patent number: 10181008
    Abstract: The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The present invention also provides methods of obtaining a quantitative score for a patient with kidney cancer based on measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The genes may be grouped into functional gene subsets for calculating the quantitative score and the gene subsets may be weighted according to their contribution to cancer recurrence.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: January 15, 2019
    Assignee: Genomic Health, Inc.
    Inventors: Steven Shak, George Andrew Watson, Michael R. Crager, Tara Maddala, Margarita Lopatin, Audrey Goddard, Dejan Knezevic, Christer Svedman
  • METHOD TO USE GENE EXPRESSION TO DETERMINE LIKELIHOOD OF CLINICAL OUTCOME OF RENAL CANCER
    Publication number: 20170121780
    Abstract: The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
    Type: Application
    Filed: December 5, 2016
    Publication date: May 4, 2017
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Wayne COWENS, Steven SHAK, Audrey GODDARD, Dejan KNEZEVIC, Joffre BAKER, Michael C. KIEFER, Tara MADDALA, Frederick L. BAEHNER
  • Method to use gene expression to determine likelihood of clinical outcome of renal cancer
    Patent number: 9551034
    Abstract: The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
    Type: Grant
    Filed: January 7, 2011
    Date of Patent: January 24, 2017
    Assignee: Genomic Health, Inc.
    Inventors: Wayne Cowens, Steven Shak, Audrey Goddard, Dejan Knezevic, Joffre Baker, Michael C. Kiefer, Tara Maddala, Frederick L. Baehner
  • GENE EXPRESSION PROFILE ALGORITHM FOR CALCULATING A RECURRENCE SCORE FOR A PATIENT WITH KIDNEY CANCER
    Publication number: 20160048632
    Abstract: The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The present invention also provides methods of obtaining a quantitative score for a patient with kidney cancer based on measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The genes may be grouped into functional gene subsets for calculating the quantitative score and the gene subsets may be weighted according to their contribution to cancer recurrence.
    Type: Application
    Filed: May 29, 2014
    Publication date: February 18, 2016
    Applicant: Genomic Health, Inc.
    Inventors: Steven SHAK, George Andrew WATSON, Michael R. CRAGER, Tara MADDALA, Margarita LOPATIN, Audrey GODDARD, Dejan KNEZEVIC, Christer SVEDMAN
  • Gene Expression Profile Algorithm and Test for Determining Prognosis of Prostate Cancer
    Publication number: 20140303002
    Abstract: The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes, or their co-expressed genes, from a biological sample obtained from a prostate cancer patient. The genes may be grouped into functional gene subsets for calculating a quantitative score useful to predict a likelihood of a clinical outcome for a prostate cancer patient.
    Type: Application
    Filed: March 21, 2014
    Publication date: October 9, 2014
    Applicant: Genomic Health, Inc.
    Inventors: Steven Shak, Mark Lee, William F. Novotny, Tara Maddala, Michael R. Crager, Diana Cherbavaz, Robert J. Pelham, Carl L. Millward, Dejan Knezevic
  • Gene expression profile algorithm and test for determining prognosis of prostate cancer
    Patent number: 8725426
    Abstract: The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes, or their co-expressed genes, from a biological sample obtained from a prostate cancer patient. The genes may be grouped into functional gene subsets for calculating a quantitative score useful to predict a likelihood of a clinical outcome for a prostate cancer patient.
    Type: Grant
    Filed: January 28, 2013
    Date of Patent: May 13, 2014
    Assignee: Genomic Health, Inc.
    Inventors: Steve Shak, Mark Lee, William Novotny, Tara Maddala, Michael Crager, Diana Cherbavaz, Robert J. Pelham, Carl L. Millward, Dejan Knezevic
  • METHOD TO USE GENE EXPRESSION TO DETERMINE LIKELIHOOD OF CLINICAL OUTCOME OF RENAL CANCER
    Publication number: 20110171633
    Abstract: The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
    Type: Application
    Filed: January 7, 2011
    Publication date: July 14, 2011
    Inventors: Wayne Cowens, Steven Shak, Audrey Goddard, Dejan Knezevic, Joffre B. Baker, Michael C. Kiefer, Tara Maddala, Frederick L. Baehner