Patents by Inventor Dejan Nikolic

Dejan Nikolic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11925736
    Abstract: Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: March 12, 2024
    Assignees: Fresenius Medical Care Deutschland GmbH, Fresenius Medical Care Holdings, Inc.
    Inventors: Massimo Earl Fini, Lynn E. Jensen, Alexander Heide, Dejan Nikolic, Arne Peters, Christoph Wiktor, Marina Wenke, Tommy Huang, Dacey John Ryan, Stefan Kreber, Lothar Leick, Dzhuney Terzi, Hendrik Therre, Manfred Weis, Alain Veneroni, Reinhold Reiter, Michele Marini, Davide Maria Benelli, Brad Yang, Jiunn Teo
  • Patent number: 11896749
    Abstract: Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.
    Type: Grant
    Filed: November 9, 2020
    Date of Patent: February 13, 2024
    Assignees: Fresenius Medical Care Deutschland GmbH, Fresenius Medical Care Holdings, Inc.
    Inventors: Massimo Earl Fini, Lynn E. Jensen, Dacey John Ryan, Alexander Heide, Dejan Nikolic, Arne Peters
  • Patent number: 11759555
    Abstract: The invention relates to a medical device comprising a printable electrical component (1), the printable electrical component (1) comprising a plastic substrate (L1) wherein at least electrical component (E) is applied to the plastic substrate, wherein the electrical component (E) comprises a dried conductive ink, wherein the plastic substrate is selected from the group comprising polycarbonate, cycloolefin copolymers, polymethylacrylate, polypropylene and wherein the dried conductive ink comprise silver and/or gold, wherein the electrical component (E) comprises feather-like and/or meander-like and/or spiral-shaped sections, whereby the medical device further comprises a fluid line, wherein the printable electrical component is located on the outside of the fluid line.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: September 19, 2023
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Dejan Nikolic, Alexander Heide, Daniel Juric, Andre Buelau, Juergen Keck, Jonathan Seybold, Karl-Peter Fritz, Kerstin Glaeser
  • Patent number: 11752247
    Abstract: Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: September 12, 2023
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Massimo Earl Fini, Tommy Huang, Dacey John Ryan, Alexander Heide, Dejan Nikolic, Arne Peters
  • Patent number: 11730871
    Abstract: Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.
    Type: Grant
    Filed: November 9, 2020
    Date of Patent: August 22, 2023
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Alexander Heide, Dejan Nikolic, Arne Peters, Christoph Wiktor
  • Patent number: 11712501
    Abstract: Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.
    Type: Grant
    Filed: November 9, 2020
    Date of Patent: August 1, 2023
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Tommy Huang, Dacey John Ryan, Alexander Heide, Dejan Nikolic, Arne Peters
  • Patent number: 11712504
    Abstract: This disclosure relates to a medical device including, a hard part, a converter, and a conductive path. The hard part has fluid paths for guiding a medical fluid, in particular blood, through the hard part. The converter is arranged to measure a characteristic of the medical fluid while the fluid is present in one of the fluid paths. At least a first section of the converter or of the conductive path is applied to or superimposed on the hard part by a first additive application method. At least a second section of the converter or of the conductive path is applied to the hard part by a second application method. The first and the second additive application methods differ from each other.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: August 1, 2023
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Alexander Heide, Dejan Nikolic
  • Publication number: 20230142123
    Abstract: To provide biotechnological filtration possibilities with which the danger of contamination is low and at the same time an optimum flow profile can be achieved, the use of a filter module 100 is proposed, the latter having, in a filter housing 110, a filter, with a bundle of hollow fibres 114, and a centrifugal pump rotor 132, for a biotechnological production method, and a filter module 100 for the filtration of a biotechnological liquid L, having a filter housing 110, a filter arranged in the filter housing 110 with a bundle of hollow fibres 114, a centrifugal pump rotor 132 arranged in the filter housing 110 such that it is fluidically connected to the interior of the hollow fibres 114, wherein the centrifugal pump rotor 132 is able to be magnetically driven such that it can force a liquid L through the hollow fibres 114, a first port 102 for the supply of a biotechnological liquid L to be filtered, which first port 102 is fluidically connected to the interior of the hollow fibres 114 of the filter, a seco
    Type: Application
    Filed: November 5, 2020
    Publication date: May 11, 2023
    Applicants: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH, UNICYTE EV AG
    Inventors: Alexander HEIDE, Dejan NIKOLIC
  • Publication number: 20230084231
    Abstract: The present invention relates to a flow sensor for measuring a flow difference having at least two measurement chambers through which fluid is conductible; at least one means for producing a magnetic field for charge separation in a fluid flowing through the at least two measurement chambers; and at least one means for measuring an electric potential in the fluid flowing through the at least two measurement chambers, with the at least two measurement chambers being arranged such that they are run through by the same magnetic field line of the magnetic field for charge separation.
    Type: Application
    Filed: January 28, 2021
    Publication date: March 16, 2023
    Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Dejan NIKOLIC, Alexander HEIDE
  • Publication number: 20230019233
    Abstract: In one aspect, a system includes a blood treatment machine; a dialyzer configured to be coupled to the blood treatment machine, the dialyzer including a dialyzer housing defining a blood inlet and a blood outlet; a bundle of hollow fibers within an interior of the dialyzer housing; a pumping device drivable to force blood received from the blood inlet through lumens of the bundle of hollow fibers and out the blood outlet; a dialysate inlet port in fluid communication with a dialysate flow path that includes space in the interior of the dialyzer housing between the bundle of hollow fibers; and a dialysate outlet port in fluid communication with the dialysate flow path. The system further includes a fluid conditioning system configured to (i) prepare and supply fresh dialysate to the dialyzer via the dialysate inlet port, and (ii) receive spent dialysate from the dialyzer via the dialysate outlet port, recycle the spent dialysate, and supply the recycled dialysate to the dialyzer via the dialysate inlet port.
    Type: Application
    Filed: December 11, 2020
    Publication date: January 19, 2023
    Inventors: Lynn E. Jensen, Stephen A. Merchant, Arne Peters, Alexander Heide, Dejan Nikolic
  • Patent number: 11517652
    Abstract: This disclosure relates to a medical device including a hard part and a converter. The hard part has fluid paths for conducting a medical fluid through the hard part. The converter is arranged to measure a characteristic of the medical fluid while the medical fluid is present in one of the fluid paths. At least a section of the converter is applied or superimposed to the hard part by at least one additive application method.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: December 6, 2022
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Alexander Heide, Dejan Nikolic
  • Publication number: 20220378993
    Abstract: This disclosure relates to a method for determining a fluid balance between a first volume flow in a first section of a fluid circuit and a second volume flow of a second section of the fluid circuit. The method may also include adjusting, assuming or detecting a first temperature in the first section of the fluid circuit and a second temperature in the second section of the fluid circuit, or detecting a temperature difference between the first and the second sections. The method may also include detecting a second volume flow in a second section of the fluid circuit and forming a balance from at least the first volume flow and a corrected value of the second volume flow. The corrected value is determined from the detected second volume flow and the second temperature and/or the temperature difference.
    Type: Application
    Filed: August 8, 2022
    Publication date: December 1, 2022
    Inventors: Petra Abel, Alexander Heide, Dejan Nikolic, Arne Peters, Elke Schulte, Christoph Wiktor
  • Publication number: 20220369471
    Abstract: The invention relates to a medical device comprising a printable electrical component (1), the printable electrical component (1) comprising a plastic substrate (L1) wherein at least electrical component (E) is applied to the plastic substrate, wherein the electrical component (E) comprises a dried conductive ink, wherein the plastic substrate is selected from the group comprising polycarbonate, cycloolefin copolymers, polymethylacrylate, polypropylene and wherein the dried conductive ink comprise silver and/or gold, wherein the electrical component (E) comprises feather-like and/or meander-like and/or spiral-shaped sections, whereby the medical device further comprises a fluid line, wherein the printable electrical component is located on the outside of the fluid line.
    Type: Application
    Filed: October 9, 2020
    Publication date: November 17, 2022
    Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Dejan NIKOLIC, Alexander HEIDE, Daniel JURIC, Andre BUELAU, Juergen KECK, Jonathan SEYBOLD, Karl-Peter FRITZ, Kerstin GLAESER
  • Patent number: 11406745
    Abstract: This disclosure relates to a method for determining a fluid balance between a first volume flow in a first section of a fluid circuit and a second volume flow of a second section of the fluid circuit. The method may also include adjusting, assuming or detecting a first temperature in the first section of the fluid circuit and a second temperature in the second section of the fluid circuit, or detecting a temperature difference between the first and the second sections. The method may also include detecting a second volume flow in a second section of the fluid circuit and forming a balance from at least the first volume flow and a corrected value of the second volume flow. The corrected value is determined from the detected second volume flow and the second temperature and/or the temperature difference.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: August 9, 2022
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Petra Abel, Alexander Heide, Dejan Nikolic, Arne Peters, Elke Schulte, Christoph Wiktor
  • Patent number: 11364375
    Abstract: The invention relates to a medical treatment apparatus comprising a tube set 20, a peristaltic pump 6 for conveying fluid, and a monitoring apparatus 15 for monitoring the occlusion of the positive displacement elements 13A, 13B of the peristaltic pump. In addition, the invention relates to a tube set 20 for a medical treatment apparatus, and to a method for monitoring the occlusion of the occlusion elements of a peristaltic pump for conveying a fluid for a medical treatment apparatus. The invention is based on the fact that the occlusion of the positive displacement elements 13A, 13B of the peristaltic pump 6 is monitored in order to monitor the fluid flow in the hose line 5.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: June 21, 2022
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Alexander Heide, Arne Peters, Dejan Nikolic
  • Publication number: 20220072209
    Abstract: Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.
    Type: Application
    Filed: November 16, 2021
    Publication date: March 10, 2022
    Inventors: Massimo Earl Fini, Tommy Huang, Dacey John Ryan, Alexander Heide, Dejan Nikolic, Arne Peters
  • Publication number: 20210283322
    Abstract: The present disclosure relates to a medical device with respectively at least one hard part with fluid paths for guiding a medical fluid, for example blood through the hard part. The medical device 200 also includes a converter and a device for determining a characteristic of the device 200. The converter is arranged to measure the characteristic of the fluid, while the fluid is present in one of the fluid paths. The characteristic may be geometric characteristic, for example, a fluid path.
    Type: Application
    Filed: March 20, 2018
    Publication date: September 16, 2021
    Inventors: Alexander Heide, Dejan Nikolic
  • Patent number: 11085588
    Abstract: The invention relates to the balancing of fluid streams in a dialysis system. In particular the invention relates to a cassette for conveying a first and a second fluid stream in a dialysis system, wherein the first and the second fluid streams can be medical fluid streams such as for example dialysate streams or blood streams, wherein the cassette has a sensor as a device for balancing the first and the second fluid stream, and wherein the sensor has a first channel for the first fluid stream and a second channel for the second fluid stream. The invention further relates to a dialysis system, which is configured to accommodate at least one cassette which is configured as described above. Furthermore, the present invention relates to an arrangement by which two channels for the first and the second fluid streams are formed. In addition, the invention relates to a method for construction of the two channels or the arrangement.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: August 10, 2021
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Dejan Nikolic, Alexander Heide
  • Patent number: 11013847
    Abstract: An external functional means comprises at least one housing body, at least one chamber integrated into the housing body for receiving medical fluids, at least one passage integrated into the housing body for receiving and/or conducting a medical fluid, and at least one valve means completely or partly integrated into the housing body for controlling or regulating a fluid flowing through the external functional means. The invention further specifies a blood treatment apparatus and methods which may be carried out by means of the external functional means of the invention and by means of the blood treatment apparatus, respectively.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: May 25, 2021
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Soeren Gronau, Goetz Guenther, Juergen Haecker, Martin Lauer, Joachim Manke, Dejan Nikolic, Manfred Weis
  • Publication number: 20210138135
    Abstract: Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.
    Type: Application
    Filed: November 9, 2020
    Publication date: May 13, 2021
    Inventors: Massimo Earl Fini, Lynn E. Jensen, Dacey John Ryan, Alexander Heide, Dejan Nikolic, Arne Peters