Abstract: A method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, causing in the biochemical and/or in the functional characteristics of the epithelial tissues during the development of tissue atypias, dysplasias, neoplasias and cancers is presented. The method is based, at least in part, on the simultaneous measurement of the spatial, temporal and spectral alterations in the characteristics of the light that is re-emitted from the tissue under examination, as a result of a combined tissue excitation with light and special chemical agents. The topical or systematic administration of these agents result in an evanescent contrast enhancement between normal and abnormal areas of tissue. The apparatus enables the capturing of temporally successive imaging in one or more spectral bands simultaneously.

Abstract: The present invention provides a method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, causing in the biochemical and/or in the functional characteristics of the epithelial tissues during the development of tissue atypias, dysplasias, neoplasias and cancers. The method is based, at least in part, on the simultaneous measurement of the spatial, temporal and spectral alterations in the characteristics of the light that is re-emitted from the tissue under examination, as a result of a combined tissue excitation with light and special chemical agents. The topical or systematic administration of these agents result in an evanescent contrast enhancement between normal and abnormal areas of tissue. The apparatus enables the capturing of temporally successive imaging in one or more spectral bands simultaneously.

Abstract: The present invention provides a method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, caused in the biochemical and/or in the functional characteristics of epithelial tissues during the development of tissue atypias, dysplasias, neoplasias and cancers. The method is based, at least in part, on the simultaneous measurement of the spatial, temporal and spectral alterations in the characteristics of the light that is re-emitted from the tissue under examination, as a result of a combined tissue excitation with light and special chemical agents. The topical or systematic administration of these agents result in an evanescent contrast enhancement between normal and abnormal areas of tissue. The apparatus enables the capturing of temporally successive imaging in one or more spectral bands simultaneously.

Abstract: This invention refers to an imaging method and apparatus capable of performing non-destructive, in situ analysis of art-objects. The invention relays on the comparison of diffuse reflectance and/or fluorescence spectra (intensity vs. wavelength), of painting material models of known composition, with the intensities emitted and captured at the same wavelengths and for any spatial point of the art-object of unknown composition. This composition, performed for any spatial point of the area of interest, improves notably the diagnostic information and enables the analysis of heterogeneous art-objects.

Abstract: This invention refers to an imaging method and apparatus capable of performing non-destructive, in situ analysis of art-objects. The invention relays on the comparison of diffuse reflectance and/or fluorescence spectra (intensity vs. wavelength), of painting material models of known composition, with the intensities emitted and captured at the same wavelengths and for any spatial point of the art-object of unknown composition. This composition, performed for any spatial point of the area of interest, improves notably the diagnostic information and enables the analysis of heterogeneous art-objects.

Abstract: The present invention provides a method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, caused in the biochemical and/or in the functional characteristics of epithelial tissues during the development of tissue atypias, dysplasias, neoplasias and cancers. The method is based, at least in part, on the simultaneous measurement of the spatial, temporal and spectral alterations in the characteristics of the light that is re-emitted from the tissue under examination, as a result of a combined tissue excitation with light and special chemical agents. The topical or systematic administration of these agents result in an evanescent contrast enhancement between normal and abnormal areas of tissue. The apparatus enables the capturing of temporally successive imaging in one or more spectral bands simultaneously.