Abstract: A syringe holder has a barrel (1) with a sleeve (2) screwed over its forward end. A syringe is entered into the rear end of the barrel (1), needle (20) first, with the sleeve (2) at its rearmost position. A coned needle cap (23) snaps through an aperture (13) at the forward end of the sleeve as a flange (18) at the rear of the syringe tube (17) abuts the rear end of the barrel (1). Screwing the sleeve (2) forwards eases the cap (23) off the needle (20), and screwing it back again leaves the assembly ready to use. The barrel (1) has finger grips (10) to facilitate thumb operation of the syringe plunger.