Abstract: The invention generally relates to polymeric particles suitable for transporting bioactive agents across mucosal barriers. The invention also relates to methods of making and using those polymeric particles.

Abstract: The invention generally relates to polymeric particles suitable for transporting bioactive agents across mucosal barriers. The invention also relates to methods of making and using those polymeric particles.

Abstract: The invention generally relates to polymeric particles suitable for transporting bioactive agents across mucosal barriers. The invention also relates to methods of making and using those polymeric particles.

Abstract: A diagnostic device includes a microscope configured to obtain image data on a plurality of cells and a computing device. The computing device is configured to receive the image data, identify at least a portion of each of the plurality of cells based on the received image data, determine at least one of a value of a morphological parameter for each identified at least a portion of the plurality of cells or a relative organization among the identified at least a portion of the plurality of cells, and calculate statistics for the plurality of cells based on the at least one of the determined values of the morphological parameter or the determined relative organization, the statistics including information suitable for distinguishing metastatic cells from non-metastatic cells. The diagnostic device further includes an output device configured to output the statistics for diagnosis.

Abstract: A diagnostic device includes a microscope configured to obtain image data on a plurality of cells and a computing device. The computing device is configured to receive the image data, identify at least a portion of each of the plurality of cells based on the received image data, determine at least one of a value of a morphological parameter for each identified at least a portion of the plurality of cells or a relative organization among the identified at least a portion of the plurality of cells, and calculate statistics for the plurality of cells based on the at least one of the determined values of the morphological parameter or the determined relative organization, the statistics including information suitable for distinguishing metastatic cells from non-metastatic cells. The diagnostic device further includes an output device configured to output the statistics for diagnosis.

Abstract: The invention generally relates to polymeric particles suitable for transporting bioactive agents across mucosal barriers. The invention also relates to methods of making and using those polymeric particles.

Abstract: A system and a method for determining the torque imposed on a filament, such as a single DNA strand or macromolecule, using a magnetic probe and an imaging device.

Abstract: A system and a method for determining the torque imposed on a filament, such as a single DNA strand or macromolecule, using a magnetic probe and an imaging device.

Abstract: The invention generally relates to polymeric particles suitable for transporting bioactive agents across mucosal barriers. The invention also relates to methods of making and using those polymeric particles.

Abstract: Methods and compositions for the reliable detection of pathogens are presented. The invention uses cells as novel pathogen detection agents, exploiting pathogen-specific pathways and apoptosis.

Abstract: A Repeated Classification Procedure (RCP) for the rapid separation, identification, classification, and quantitation of proteins in a mixture of proteins utilizes general-motif antibodies which typically bind to a plurality of proteins in a mixture which have a common motif or are homologs in some respect. By repeatedly using general-motif antibodies or using general-motif antibodies in conjunction with specific antibodies, a pattern of binding can be produced which uniquely identifies proteins of interest. By using immobilized general-motif antibodies to effect separation, the identification, classification, and quantitation of proteins in a sample can be use to characterize the protein synthesis pattern of disease states. Quantitation of protein in a sample can be determined based on the movement of very small beads with bound protein in a magnetic field, wherein larger quantities of bound protein causes the beads to travel relatively smaller distances or at relatively slower rates.