Patents by Inventor Denise C. Manker

Denise C. Manker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120114610
    Abstract: This invention provides a novel endophytic fungus, Muscodor, that produces a mixture of volatile antibiotics with activity on specific plant pathogens, bacteria, nematodes and insects. Also provided is a method for treating or protecting plants, soil and seeds from microbial infections comprising applying an effective amount of a volatile antibiotic producing Muscodor sp. The invention also relates to fungicidal, bactericidal, insecticidal and nematicidal compositions comprising this novel Muscodor strain and the antibiotics and metabolites produced by this strain either alone, or in combination with other chemical and biological pesticides. Also provided is a method for identifying and isolating related gas producing fungi.
    Type: Application
    Filed: December 2, 2011
    Publication date: May 10, 2012
    Inventors: Gary Strobel, Denise C. Manker, Julien Mercier
  • Patent number: 8093024
    Abstract: This invention provides a novel endophytic fungus, Muscodor, that produces a mixture of volatile antibiotics with activity on specific plant pathogens, bacteria, nematodes and insects. Also provided is a method for treating or protecting plants, soil and seeds from microbial infections comprising applying an effective amount of a volatile antibiotic producing Muscodor sp. The invention also relates to fungicidal, bactericidal, insecticidal and nematicidal compositions comprising this novel Muscodor strain and the antibiotics and metabolites produced by this strain either alone, or in combination with other chemical and biological pesticides. Also provided is a method for identifying and isolating related gas producing fungi.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: January 10, 2012
    Inventors: Gary Strobel, Denise C. Manker, Julien Mercier
  • Publication number: 20100285543
    Abstract: This invention provides a novel endophytic fungus, Muscodor, that produces a mixture of volatile antibiotics with activity on specific plant pathogens, bacteria, nematodes and insects. Also provided is a method for treating or protecting plants, soil and seeds from microbial infections comprising applying an effective amount of a volatile antibiotic producing Muscodor sp. The invention also relates to fungicidal, bactericidal, insecticidal and nematicidal compositions comprising this novel Muscodor strain and the antibiotics and metabolites produced by this strain either alone, or in combination with other chemical and biological pesticides. Also provided is a method for identifying and isolating related gas producing fungi.
    Type: Application
    Filed: May 25, 2010
    Publication date: November 11, 2010
    Inventors: Gary Strobel, Denise C. Manker, Julien Mercier
  • Patent number: 7754203
    Abstract: This invention provides a novel endophytic fungus, Muscodor, that produces a mixture of volatile antibiotics with activity on specific plant pathogens, bacteria, nematodes and insects. Also provided is a method for treating or protecting plants, soil and seeds from microbial infections comprising applying an effective amount of a volatile antibiotic producing Muscodor sp. The invention also relates to fungicidal, bactericidal, insecticidal and nematicidal compositions comprising this novel Muscodor strain and the antibiotics and metabolites produced by this strain either alone, or in combination with other chemical and biological pesticides. Also provided is a method for identifying and isolating related gas producing fungi.
    Type: Grant
    Filed: May 17, 2005
    Date of Patent: July 13, 2010
    Assignee: AgraQuest, Inc.
    Inventors: Gary Strobel, Denise C. Manker, Julien Mercier
  • Patent number: 6911338
    Abstract: This invention provides a novel endophytic fungus, Muscodor, that produces a mixture of volatile antibiotics with activity on specific plant pathogens, bacteria, nemotodes and insects. Also provided is a method for treating or protecting plants, soil and seeds from microbial infections comprising applying an effective amount of a volatile antibiotic producing Muscodor sp. The invention also relates to fungicidal, bactericidal, insecticidal and nematicidal compositions comprising this novel Muscodor strain and the antibiotics and metabolites produced by this strain either alone, or in combination with other chemical and biological pesticides. Also provided is a method for identifying and isolating related gas producing fungi.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: June 28, 2005
    Inventors: Gary Strobel, Denise C. Manker, Julien Mercier
  • Publication number: 20030186425
    Abstract: This invention provides a novel endophytic fungus, Muscodor, that produces a mixture of volatile antibiotics with activity on specific plant pathogens, bacteria, nematodes and insects. Also provided is a method for treating or protecting plants, soil and seeds from microbial infections comprising applying an effective amount of a volatile antibiotic producing Muscodor sp. The invention also relates to fungicidal, bactericidal, insecticidal and nematicidal compositions comprising this novel Muscodor strain and the antibiotics and metabolites produced by this strain either alone, or in combination with other chemical and biological pesticides. Also provided is a method for identifying and isolating related gas producing fungi.
    Type: Application
    Filed: April 11, 2002
    Publication date: October 2, 2003
    Inventors: Gary Strobel, Denise C. Manker, Julien Mercier
  • Patent number: 6538027
    Abstract: This invention provides compositions for repelling insects, particularly biting insects, such as mosquitoes, ticks, and biting flies comprising ratite oil, active fractions of ratite oil obtained by flash chromatography or compositions comprising mixtures of fatty acids found in ratite oil. Also provided are compositions for repelling insects comprising ratite oil, active fractions of ratite oil or compositions comprising mixtures of fatty acids found in ratite oil further comprising at least one additional insect repellent. Methods of repelling insects, particularly biting insects, are provided comprising topically applying ratite oil, active fractions of ratite oil, or compositions comprising mixtures of fatty acids found in ratite oil; or ratite oil, active fractions thereof, or compositions comprising fatty acids found in ratite oil and further comprising at least one additional insect repellent.
    Type: Grant
    Filed: February 15, 2001
    Date of Patent: March 25, 2003
    Assignee: AgraQuest, Inc.
    Inventors: Denise C. Manker, Pamela Gail Marrone, Stephen Judd
  • Patent number: 6406691
    Abstract: The present invention relates to a factor that potentiates the pesticidal activity of a Bacillus related pesticide as well as methods for isolating and identifying said factor. The invention further relates to pesticidal compositions comprising the factor as well as methods of using the pesticidal compositions to control a pest and decrease the resistance of a pest to a pesticide and potentiate a Bacillus related pesticide.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: June 18, 2002
    Assignee: Valent Biosciences Corp.
    Inventors: Denise C. Manker, William D. Lidster, Susan C. MacIntosh, Robert L. Starnes
  • Publication number: 20010010813
    Abstract: This invention provides compositions for repelling insects, particularly biting insects, such as mosquitoes, ticks, and biting flies comprising ratite oil, active fractions of ratite oil obtained by flash chromatography or compositions comprising mixtures of fatty acids found in ratite oil. Also provided are compositions for repelling insects comprising ratite oil, active fractions of ratite oil or compositions comprising mixtures of fatty acids found in ratite oil further comprising at least one additional insect repellent. Methods of repelling insects, particularly biting insects, are provided comprising topically applying ratite oil, active fractions of ratite oil, or compositions comprising mixtures of fatty acids found in ratite oil; or ratite oil, active fractions thereof, or compositions comprising fatty acids found in ratite oil and further comprising at least one additional insect repellent.
    Type: Application
    Filed: February 15, 2001
    Publication date: August 2, 2001
    Inventors: Denise C. Manker, Pamela Gail Marrone, Stephen Judd
  • Patent number: 6077506
    Abstract: The present invention provides a novel Bacillus thuringiensis strain that exhibits broad antifungal and antibacterial activity. The invention also provides the use of the Bacillus thuringiensis strain or the antibiotic produced by the strain for control of a broad range of fungal and bacterial plant pathogens.
    Type: Grant
    Filed: April 22, 1999
    Date of Patent: June 20, 2000
    Assignees: AgraQuest, Inc., BioDiscovery New Zealand Ltd.
    Inventors: Pamela Gail Marrone, Sherry D. Heins, Denise C. Manker, Desmond R. Jimenez, Chris N. Chilcott, Peter Wigley, Andrew Broadwell
  • Patent number: 6004774
    Abstract: The present invention is directed to a unique strain of Bacillus subtilis for inhibiting growth of plant pathogenic fungi and bacteria and methods for treating or protecting plants from fingal and bacterial infections.
    Type: Grant
    Filed: November 25, 1998
    Date of Patent: December 21, 1999
    Assignee: Agritope, Inc.
    Inventors: Pamela Gail Marrone, Sherry D. Heins, Denise C. Manker, Desmond R. Jimenez, Richard K. Bestwick, George J. Vandemark
  • Patent number: 5976563
    Abstract: The invention is related to a novel strain(s) of Bacillus thuringiensis in which essentially all of the pesticidal activity of said strain is in the supernatant of a fermentation of said strain. The strain produces a substance which has activity against an insect pest(s) of the order Coleoptera and which enhances the pesticidal activity of a Bacillus related pesticide. The invention further relates to pesticidal compositions comprising the substance and a pesticidal carrier, or the substance and a Bacillus related pesticide, a chemical pesticide and/or a virus with pesticidal properties as well as methods of using the pesticidal compositions to control a pest.
    Type: Grant
    Filed: October 8, 1997
    Date of Patent: November 2, 1999
    Assignee: Abbott Laboratories
    Inventors: Chi-Li Liu, Anita M. MacMullan, Patricia Ann Lufburrow, Robert L. Starnes, Denise C. Manker
  • Patent number: 5976564
    Abstract: The invention is related to a novel strain(s) of Bacillus thuringiensis in which essentially all of the pesticidal activity of said strain is in the supernatant of a fermentation of said strain. The strain produces a substance which has activity against an insect pest(s) of the order Coleoptera and which enhances the pesticidal activity of a Bacillus related pesticide. The invention further relates to pesticidal compositions comprising the substance and a pesticidal carrier, or the substance and a Bacillus related pesticide, a chemical pesticide and/or a virus with pesticidal properties as well as methods of using the pesticidal compositions to control a pest.
    Type: Grant
    Filed: October 8, 1997
    Date of Patent: November 2, 1999
    Assignee: Abbott Laboratories
    Inventors: Chi-Li Liu, Anita M. MacMullan, Patricia Ann Lufburrow, Robert L. Starnes, Denise C. Manker
  • Patent number: 5929113
    Abstract: This invention provides a method for repelling biting insects such as mosquitoes, ticks, and biting flies by topically applying to the skin of a subject emu oil, fractions of emu oil obtained by flash chromatography or a composition comprising emu oil or active fractions thereof and at least one other insect repellent such as citronella, DEET or saponin. Also provided are compositions for repelling biting insects comprising diluted fractions of emu oil, and compositions comprising emu oil or active fractions thereof and at least one other insect repellent such as citronella, DEET or saponin.
    Type: Grant
    Filed: June 16, 1997
    Date of Patent: July 27, 1999
    Assignee: AgraQuest, Inc.
    Inventors: Denise C. Manker, Pamela Gail Marrone, Stephen Judd
  • Patent number: 5919447
    Abstract: The present invention provides a Bacillus thuringiensis strain that exhibits broad antifungal and antibacterial activity. The invention also provides the use of the Bacillus thuringiensis strain or the antibiotic produced by the strain for control of a broad range of fungal and bacterial plant pathogens.
    Type: Grant
    Filed: January 22, 1997
    Date of Patent: July 6, 1999
    Assignee: Agraquest, Inc.
    Inventors: Pamela Gail Marrone, Sherry D. Heins, Denise C. Manker, Desmond R. Jimenez, Chris N. Chilcott, Peter Wigley, Andrew Broadwell
  • Patent number: 5801196
    Abstract: This invention provides a method for repelling biting insects such as mosquitoes by topically applying to the skin of a subject fractions of emu oil obtained by flash chromatography. Also provided are methods for repelling biting insects by topically applying diluted fractions of emu oil. The invention also provides a compound useful in repelling biting insects having the NMR spectrum of FIG. 3, that is ultra violet light sensitive and is reactive to vanillin/sulfuric acid. Also provided are compounds useful in repelling biting insects having the NMR spectrum of FIG. 4, that is not ultra violet light sensitive and is not reactive to vanillin/sulfuric acid.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: September 1, 1998
    Assignees: AgraQuest, Inc., P.E. Zogen
    Inventors: Denise C. Manker, Pamela Gail Marrone, Stephen Judd
  • Patent number: 5753222
    Abstract: The present invention relates to a novel strain antibiotic-producing Bacillus subtilis which is effective against plant fungal and bacterial infections. The invention also includes methods of protecting plants from fungal and bacterial infections comprising the step of applying to the plant an effective amount of the antibiotic-producing Bacillus subtilis, the antibiotic produced by the antibiotic-producing Bacillus subtilis or a combination thereof, optionally further comprising another antibiotic-producing bacterial strain and/or a chemical pesticide. The invention includes methods of treating fungal and bacterial infections using whole broth cultures or supernatants obtained from cultures of antibiotic-producing Bacillus subtilis cultures. The invention also includes treating plant infections using a combination of whole broth and/or supernatant obtained from the antibiotic-producing strain of Bacillus subtilis optionally in combination with chemical pesticides.
    Type: Grant
    Filed: November 18, 1996
    Date of Patent: May 19, 1998
    Assignee: Agritope, Inc.
    Inventors: Pamela Gail Marrone, Sherry D. Heins, Denise C. Manker, Desmond R. Jimenez, Richard K. Bestwick, George J. Vandemark
  • Patent number: 5733544
    Abstract: The present invention relates to a newly discovered Bacillus sp. strain which exhibits pesticidal activity. The supernatant of cultures of this novel isolate are also effective pesticidal agents. Also provided are methods of using the novel strain or supernatant for treatment or prevention of disease in plants or animals.
    Type: Grant
    Filed: November 18, 1996
    Date of Patent: March 31, 1998
    Assignees: University of Saskatchewan, Agraquest, Inc.
    Inventors: Pamela Gail Marrone, Denise C. Manker, Sherry D. Heins, Desmond R. Jimenez, James J. Germida
  • Patent number: 5677338
    Abstract: This invention provides a method for repelling biting insects such as mosquitoes by topically applying to the skin of a subject fractions of emu oil obtained by flash chromatography. Also provided are methods for repelling biting insects by topically applying diluted fractions of emu oil. The invention also provides a compound useful in repelling biting insects having the NMR spectrum of FIG. 3, that is ultra violet light sensitive and is reactive to vanillin/sulfuric acid. Also provided are compounds useful in repelling biting insects having the NMR spectrum of FIG. 4, that is not ultra violet light sensitive and is not reactive to vanillin/sulfuric acid.
    Type: Grant
    Filed: November 18, 1996
    Date of Patent: October 14, 1997
    Assignee: AgraQuest, Inc.
    Inventors: Denise C. Manker, Pamela Gail Marrone, Stephen Judd
  • Patent number: 5491122
    Abstract: The present invention provides fungicidal and insecticidal active compounds and derivatives thereof, fungicidal and insecticidal compositions comprising said compounds, processes for producing said compounds and the use of said compounds for controlling fungi and/or insects.
    Type: Grant
    Filed: December 7, 1994
    Date of Patent: February 13, 1996
    Assignees: Novo Nordisk A/S, Novo Nordisk Entotech, Inc.
    Inventors: Denise C. Manker, Connie N. Rosendahl, Morten Heide, Torben L. Bachmann, Ruby I. Nielsen