Patents by Inventor Denise Carol Manker

Denise Carol Manker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6852317
    Abstract: A novel antibiotic-producing Streptomyces sp. is provided that exhibits antifungal activity only on certain specific plant pathogens. Also provided is a method of treating or protecting plants from fungal infections comprising applying an effective amount of an antibiotic-producing Streptomyces sp. having all the identifying characteristics of NRRL Accession number B-30145. The invention also relates to fungicidal compositions comprising this novel Streptomyces strain and the antibiotics and metabolites produced by this strain either alone, or in combination with other chemical and biological pesticides.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: February 8, 2005
    Assignee: AgraQuest, Inc.
    Inventors: Lori Jo Lehman, Randy Jay McCoy, Caiyao Yuan, Denise Carol Manker, Jimmy Ensio Orjala, Pamela Gail Marrone, Jorge Isaac Jimenez Santamaria
  • Patent number: 6844182
    Abstract: This invention is directed to Bacillus mutants which produce a factor which potentiates the pesticidal activity of a Bacillus related pesticide, a chemical pesticide and/or a virus with pesticidal properties.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: January 18, 2005
    Assignee: Valent BioSciences Corporation
    Inventors: Helle Outtrup, William D. Lidster, Susan C. MacIntosh, Robert L. Starnes, Denise Carol Manker
  • Publication number: 20040141955
    Abstract: This invention provides pesticidally effective compositions related to a novel endophytic fungi named Muscodor. Specifically, the invention relates to commercially useful formulations of Muscodor and methods for preparing such formulations. It also provides various synthetic pesticidal mixtures of volatile organic compounds isolatable from Muscodor grown on various substrates. Also provided are methods for inhibiting the growth of organisms, such as microbes, insects, and nematodes by exposing such organisms or the habitats thereof to the above Muscodor-related compositions.
    Type: Application
    Filed: July 17, 2003
    Publication date: July 22, 2004
    Inventors: Gary A. Strobel, Denise Carol Manker, Julien Mercier, Jorge Jimenez, John Lin, Jonathan Thurston, Barry Kersting
  • Patent number: 6682925
    Abstract: A novel strain of Streptomyces galbus that produces metabolites and exhibits pesticidal activity is disclosed. In addition, a supernatant of the novel strain with pesticidal activity is disclosed. An ethyl acetate-soluble, small molecular weight, alkali stable, metabolite produced by the novel strain Streptomyces galbus with pesticidal activity against lepidopteran insects is provided. Also included are methods for fermenting the novel strain of Streptomyces galbus and increasing the bioactivity of the pesticidal activity. Also included are methods for protecting or treating plants from caterpillars comprising the step of applying to a plant an effective amount of the novel Streptomyces galbus strain, the metabolites produced by the strain, or a combination thereof.
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: January 27, 2004
    Assignee: AgraQuest, Inc.
    Inventors: Lori Jo Lehman, Jimmy Ensio Orjala, Denise Carol Manker, Desmond Rito Jimenez, Nancy Ann Baum, Pamela Gail Marrone
  • Patent number: 6638910
    Abstract: The present invention relates to a novel antibiotic-producing and metabolite-producing Bacillus subtilis strain that exhibits insecticidal, antifungal and antibacterial activity. The supernatant of this novel strain contains effective insecticidal, antifungal and antibacterial agents. Also included in the invention is a solvent extractable, small molecular weight (<10,000 daltons) corn rootworm-active metabolite produced in the supernatant. Also included in the invention are methods of protecting or treating plants from fungal and bacterial infections and corn rootworm infestations comprising the step of applying to the plant an effective amount of the antibiotic/metabolite-producing novel Bacillus subtilis strain, the antibiotic/metabolite produced by the novel Bacillus subtilis strain or a combination thereof, optionally further comprising another antibiotic-producing bacterial strain and/or a chemical pesticide.
    Type: Grant
    Filed: November 27, 2001
    Date of Patent: October 28, 2003
    Assignee: AgraQuest, Inc.
    Inventors: Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jimenez, Randy Jay McCoy, Pamela Gail Marrone, Jimmy Ensio Orjala
  • Patent number: 6635245
    Abstract: A novel antibiotic-producing Bacillus sp. is provided that exhibits antifungal activity only on certain specific plant pathogens and no antibacterial activity is provided by this invention, as well as a biologically pure culture of a strain having all the identifying characteristics of this strain. Also provided is a method of treating or protecting plants, fruit and roots from fungal infections by applying an effective amount of these strains, supernatants produced by these strains or a metabolite isolated from these strains. The invention further encompasses the synergistic fungicidal effect of using a strain of NRRL Accession Nos. B-30087 together with B-21661 (AQ 713).
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: October 21, 2003
    Assignee: AgraQuest, Inc.
    Inventors: Lori Jo Lehman, Randy J. McCoy, Belinda Jane Messenger, Denise Carol Manker, Jimmy Ensio Orjala, Dorte Lindhard, Pamela Gail Marrone, Desmond Rito Jimenez
  • Publication number: 20030186852
    Abstract: The present invention relates to a novel antibiotic-producing and metabolite-producing Bacillus subtilis strain that exhibits insecticidal, antifungal and antibacterial activity. The supernatant of this novel strain contains effective insecticidal, antifungal and antibacterial agents. Also included in the invention is a solvent extractable, small molecular weight (<10,000 daltons) corn rootworm-active metabolite produced in the supernatant. Also included in the invention are methods of protecting or treating plants from fungal and bacterial infections and corn rootworm infestations comprising the step of applying to the plant an effective amount of the antibiotic/metabolite-producing novel Bacillus subtilis strain, the antibiotic/metabolite produced by the novel Bacillus subtilis strain or a combination thereof, optionally further comprising another antibiotic-producing bacterial strain and/or a chemical pesticide.
    Type: Application
    Filed: November 27, 2001
    Publication date: October 2, 2003
    Inventors: Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jimenez, Randy Jay McCoy, Pamela Gail Marrone, Jimmy Ensio Orjala
  • Patent number: 6586231
    Abstract: A novel antibiotic-producing Bacillus sp. is provided that exhibits antifungal activity only on certain specific plant pathogens and no antibacterial activity is provided by this invention as well as a biologically pure culture of a strain having all the identifying characteristics of this strain. Also provided is a method of treating or protecting plants, fruit and roots from fungal infections by applying an effective amount of these strains, supernatants produced by these strains or a metabolite isolated from these strains.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: July 1, 2003
    Assignee: AgraQuest, Inc.
    Inventors: Lori Jo Lehman, Randy Jay McCoy, Belinda Jane Messenger, Denise Carol Manker, Jimmy Ensio Orjala, Dorte Lindhard, Pamela Gail Marrone
  • Patent number: 6524577
    Abstract: A novel antibiotic-producing Streptomyces sp. is provided that exhibits antifungal activity only on certain specific plant pathogens. Also provided is a method of treating or protecting plants from fungal infections comprising applying an effective amount of an antibiotic-producing Streptomyces sp. having all the identifying characteristics of NRRL Accession number B-30145. The invention also relates to fungicidal compositions comprising this novel Streptomyces strain and the antibiotics and metabolites produced by this strain either alone, or in combination with other chemical and biological pesticides.
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: February 25, 2003
    Assignee: AgraQuest, Inc.
    Inventors: Lori Jo Lehman, Randy Jay McCoy, Cai-yao Yuan, Denise Carol Manker, Jimmy Ensio Orjala, Pamela Gail Marrone
  • Publication number: 20030031741
    Abstract: A novel antibiotic-producing Streptomyces sp. is provided that exhibits antifungal activity only on certain specific plant pathogens. Also provided is a method of treating or protecting plants from fungal infections comprising applying an effective amount of an antibiotic-producing Streptomyces sp. having all the identifying characteristics of NRRL Accession number B-30145. The invention also relates to fungicidal compositions comprising this novel Streptomyces strain and the antibiotics and metabolites produced by this strain either alone, or in combination with other chemical and biological pesticides.
    Type: Application
    Filed: September 27, 2001
    Publication date: February 13, 2003
    Inventors: Lori Jo Lehman, Randy Jay McCoy, Caiyao Yuan, Denise Carol Manker, Jimmy Ensio Orjala, Pamela Gail Marrone, Jorge Isaac Jimenez Santamaria
  • Patent number: 6417163
    Abstract: The present invention relates to a novel antibiotic-producing and metabolite-producing Bacillus subtilis strain that exhibits insecticidal, antifungal and antibacterial activity. The supernatant of this novel strain contains effective insecticidal, antifungal and antibacterial agents. Also included in the invention is a solvent extractable, small molecular weight (<10,000 daltons) corn rootworm-active metabolite produced in the supernatant. Also included in the invention are methods of protecting or treating plants from fungal and bacterial infections and corn rootworm infestations comprising the step of applying to the plant an effective amount of the antibiotic/metabolite-producing novel Bacillus subtilis strain, the antibiotic/metabolite produced by the novel Bacillus subtilis strain or a combination thereof, optionally further comprising another antibiotic-producing bacterial strain and/or a chemical pesticide.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: July 9, 2002
    Assignee: AgraQuest, Inc.
    Inventors: Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jimenez, Randy Jay McCoy, Pamela Gail Marrone, Jimmy Ensio Orjala
  • Publication number: 20020004237
    Abstract: This invention is directed to Bacillus mutants which produce a factor which potentiates the pesticidal activity of a Bacillus related pesticide, a chemical pesticide and/or a virus with pesticidal properties.
    Type: Application
    Filed: May 15, 2001
    Publication date: January 10, 2002
    Inventors: Helle Outtrup, William D. Lidster, Susan C. MacIntosh, Robert L. Starnes, Denise Carol Manker
  • Publication number: 20010022968
    Abstract: A novel antibiotic-producing Bacillus sp. is provided that exhibits antifungal activity only on certain specific plant pathogens and no antibacterial activity is provided by this invention as well as a biologically pure culture of a strain having all the identifying characteristics of this strain. Also provided is a method of treating or protecting plants, fruit and roots from fungal infections by applying an effective amount of these strains, supernatants produced by these strains or a metabolite isolated from these strains.
    Type: Application
    Filed: December 15, 2000
    Publication date: September 20, 2001
    Inventors: Lori Jo Lehman, Randy Jay McCoy, Belinda Jane Messenger, Denise Carol Manker, Jimmy Ensio Orjala, Dorte Lindhard, Pamela Gail Marrone
  • Patent number: 6291426
    Abstract: The present invention relates to a novel antibiotic-producing and metabolite-producing Bacillus subtilis strain that exhibits insecticidal, antifungal and antibacterial activity. The supernatant of this novel strain contains effective insecticidal, antifungal and antibacterial agents. Also included in the invention is a solvent extractable, small molecular weight (<10,000 daltons) corn rootworm-active metabolite produced in the supernatant. Also included in the invention are methods of protecting or treating plants from fungal and bacterial infections and corn rootworm infestations comprising the step of applying to the plant an effective amount of the antibiotic/metabolite-producing novel Bacillus subtilis strain, the antibiotic/metabolite produced by the novel Bacillus subtilis strain or a combination thereof, optionally further comprising another antibiotic-producing bacterial strain and/or a chemical pesticide.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: September 18, 2001
    Assignee: AgraQuest, Inc.
    Inventors: Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jimenéz, Randy Jay McCoy, Pamela Gail Marrone, Jimmy Ensio Orjala
  • Patent number: 6277624
    Abstract: This invention is directed to Bacillus mutants which produce a factor which potentiates the pesticidal activity of a Bacillus related pesticide, a chemical pesticide and/or a virus with pesticidal properties.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: August 21, 2001
    Assignee: Valent BioSciences, Inc.
    Inventors: Helle Outtrup, William D. Lidster, Susan C. MacIntosh, Robert L. Starnes, Denise Carol Manker
  • Patent number: 6268181
    Abstract: This invention is directed to a method for obtaining a factor which potentiates the pesticidal activity of a Bacillus related pesticide, a chemical pesticide and/or a virus with pesticidal properties.
    Type: Grant
    Filed: January 28, 1998
    Date of Patent: July 31, 2001
    Assignee: Valent BioSciences, Corporation
    Inventors: Denise Carol Manker, William D. Lidster, Susan C. MacIntosh, Robert L. Starnes
  • Patent number: 6245551
    Abstract: A novel antibiotic-producing Bacillus sp. is provided that exhibits antifungal activity only on certain specific plant pathogens and no antibacterial activity is provided by this invention as well as a biologically pure culture of a strain having all the identifying characteristics of this strain. Also provided is a method of treating or protecting plants, fruit and roots from fungal infections by applying an effective amount of these strains, supernatants produced by these strains or a metabolite isolated from these strains.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: June 12, 2001
    Assignee: AgraQuest, Inc.
    Inventors: Lori Jo Lehman, Randy Jay McCoy, Belinda Jane Messenger, Denise Carol Manker, Jimmy Ensio Orjala, Dorte Lindhard, Pamela Gail Marrone
  • Patent number: 6239103
    Abstract: The present invention relates to a novel antibiotic-producing and metabolite-producing Bacillus subtilis strain that exhibits insecticidal, antifungal and antibacterial activity. The supernatant of this novel strain contains effective insecticidal, antifungal and antibacterial agents. Also included in the invention is a solvent extractable, small molecular weight (<10,000 daltons) corn rootworm-active metabolite produced in the supernatant. Also included in the invention are methods of protecting or treating plants from fungal and bacterial infections and corn rootworm infestations comprising the step of applying to the plant an effective amount of the antibiotic/metabolite-producing novel Bacillus subtilis strain, the antibiotic/metabolite produced by the novel Bacillus subtilis strain or a combination thereof, optionally further comprising another antibiotic-producing bacterial strain and/or a chemical pesticide.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: May 29, 2001
    Assignee: AgraQuest, Inc.
    Inventors: Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jimenéz, Randy Jay McCoy, Pamela Gail Marrone, Jimmy Ensio Orjala
  • Patent number: 6210665
    Abstract: A novel pesticidal metabolite-producing B. mycoides strain is provided. In addition, a supernatant of the novel strain with pesticidal activity is provided. A water-soluble, small molecular weight (<10,000 daltons) metabolite produced by the novel strain of Bacillus mycoides with pesticidal activity against corn rootworm is provided. Also included are methods for protecting or treating plants from insect infestations comprising the step of applying to the plant an effective amount of the novel Bacillus mycoides strain, the metabolite produced by the novel strain or a combination thereof, optionally, further comprising applying another pesticidal metabolite-producing bacterial strain and/or a chemical pesticide.
    Type: Grant
    Filed: August 19, 1998
    Date of Patent: April 3, 2001
    Assignee: AgraQuest, Inc.
    Inventors: Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jiménez, Pamela Gail Marrone
  • Patent number: 6103228
    Abstract: The present invention relates to a novel antibiotic-producing and metabolite-producing Bacillus subtilis strain that exhibits insecticidal, antifungal and antibacterial activity. The supernatant of this novel strain contains effective insecticidal, antifungal and antibacterial agents. Also included in the invention is a solvent extractable, small molecular weight (<10,000 daltons) corn rootworm-active metabolite produced in the supernatant. Also included in the invention are methods of protecting or treating plants from fungal and bacterial infections and corn rootworm infestations comprising the step of applying to the plant an effective amount of the antibiotic/metabolite-producing novel Bacillus subtilis strain, the antibiotic/metabolite produced by the novel Bacillus subtilis strain or a combination thereof, optionally further comprising another antibiotic-producing bacterial strain and/or a chemical pesticide.
    Type: Grant
    Filed: December 30, 1998
    Date of Patent: August 15, 2000
    Assignee: AgraQuest, Inc.
    Inventors: Sherry Darlene Heins, Denise Carol Manker, Desmond Rito Jimenez, Randy Jay McCoy, Pamela Gail Marrone, Jimmy Ensio Orjala