Patents by Inventor Dennis J. Goebel

Dennis J. Goebel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic-GluR6 analogs, methods of treatment and use
    Patent number: 10046024
    Abstract: A composition which is reversible inhibitor of at least one neuron-specific PDZ domain comprising wherein R is a molecular transporter with or without a linker amino acid; R1 is at least about one amino acid covalently bound; and, R2 is isoleucine, leucine, alanine, phenylalanine, or valine, and methods of use.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: August 14, 2018
    Assignee: The United States of America, as represented by National Institutes of Health (NIH), U.S. Dept of Health and Human Services (DHHS), NIH Division of Extramural Inventions and Technology Resource (DEITR)
    Inventors: Mark Spaller, John Marshall, Dennis J. Goebel
  • Neuroprotective composition and method of use
    Patent number: 10040822
    Abstract: A therapeutic composition for treating brain injury comprising a polyarginine peptide of from 5 to 9 arginines (SEQ ID NO: 1), and further comprising 1 or more terminal cysteines. The composition is administered in therapeutically effective dosages prophylactically or as soon as possible post-injury in treating neuronal injury.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: August 7, 2018
    Assignee: National Institutes of Health, U.S. Dept. of Health and Human Services, NIH Division of Extramural Inventions and Technology Resources
    Inventors: Dennis J. Goebel, John Marshall
  • NEUROPROTECTIVE COMPOSITION AND METHOD OF USE
    Publication number: 20170107253
    Abstract: A therapeutic composition for treating brain injury comprising a polyarginine peptide of from 5 to 9 arginines, and further comprising 1 or more terminal cysteines. The composition is administered in therapeutically effective dosages prophylactically or as soon as possible post-injury in treating neuronal injury.
    Type: Application
    Filed: December 29, 2016
    Publication date: April 20, 2017
    Inventors: Dennis J. Goebel, John Marshall
  • CYCLIC-GLUR6 ANALOGS, METHODS OF TREATMENT AND USE
    Publication number: 20160303186
    Abstract: A composition which is reversible inhibitor of at least one neuron-specific PDZ domain comprising wherein R is a molecular transporter with or without a linker amino acid; R1 is at least about one amino acid covalently bound; and, R2 is isoleucine, leucine, alanine, phenylalanine, or valine, and methods of use.
    Type: Application
    Filed: June 28, 2016
    Publication date: October 20, 2016
    Inventors: Mark Spaller, John Marshall, Dennis J. Goebel
  • Cyclic-GluR6 analogs, methods of treatment and use
    Patent number: 9403876
    Abstract: A composition which is reversible inhibitor of at least one neuron-specific PDZ domain comprising wherein R is a molecular transporter with or without a linker amino acid; R1 is at least about one amino acid covalently bound; and, R2 is isoleucine, leucine, alanine, phenylalanine, or valine, and methods of use.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: August 2, 2016
    Assignee: Brown University
    Inventors: Mark Spaller, John Marshall, Dennis J. Goebel
  • NEUROPROTECTIVE COMPOSITION AND METHOD OF USE
    Publication number: 20150126457
    Abstract: A therapeutic composition for treating brain injury comprising a polyarginine peptide of from 5 to 9 arginines, and further comprising 1 or more terminal cysteines. The composition is administered in therapeutically effective dosages prophylactic ally as soon as possible post-injury in treating neuronal injury.
    Type: Application
    Filed: April 17, 2013
    Publication date: May 7, 2015
    Inventors: Dennis J. Goebel, John Marshall
  • CYCLIC-GLUR6 ANALOGS, METHODS OF TREATMENT AND USE
    Publication number: 20120220535
    Abstract: A composition which is reversible inhibitor of at least one neuron-specific PDZ domain comprising wherein R is a molecular transporter with or without a linker amino acid; R1 is at least about one amino acid covalently bound; and, R2 is isoleucine, leucine, alanine, phenylalanine, or valine, and methods of use.
    Type: Application
    Filed: May 18, 2010
    Publication date: August 30, 2012
    Inventors: Mark Spaller, John Marshall, Dennis J. Goebel