Abstract: The invention relates to medical implants, including spinal implants and bone grafts, for fixation and integration with hard tissue. The bone medical implants include at least one rotational fixation mechanism that further includes or is attached to one or more sharp protrusions configured to penetrate and become lodged into hard tissue to provide support and positional stability. Such support is useful to ensure that the spinal bone graft may be used without additional stabilizing or anchoring structures, such as supporting plates or screws.

Abstract: The present invention relates to antibodies binding to 5T4, including bispecific antibodies binding to 5T4 and CD3. The invention further provides pharmaceutical compositions comprising the antibodies and use of the antibodies for therapeutic and diagnostic procedures, in particular in cancer therapy.

Abstract: Chlorine-containing polyethylene- and polyether-based elastomer compositions having excellent heat resistance and chemical resistance, which are heat stabilized with from about 1 to about 25 parts per hundred weight of the elastomer of barium sulfate, and high temperature and chemical resistant molded and extruded products including automotive hose and cable jacketing incorporating such elastomer compositions.

Abstract: A shock-absorbing torsionally elastic power transmitting device is described having resilient cushioning means loaded with modulus-increasing fibrous reinforcement, adapted to be interposed between mating lugs of a hub and rim configured to accommodate high torque levels simultaneously with relatively large angular deflections. The fibrous reinforcement is preferably aligned in the principal direction of displacement of the cushions under load. In another aspect, a torsionally elastic power transmitting device is used with V- or V-ribbed belt friction drive sheaves subject to slippage, to absorb torsional shocks and minimize heat build-up.