Patents by Inventor Dennis Koehn
Dennis Koehn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240169540Abstract: Computer-implemented methods and systems are provided for charactering a property of microvascular tissue that is supplied with blood via a coronary artery under investigation, which involve obtaining an x-ray angiographic image sequence of the coronary artery under investigation acquired while contrast agent flows into and through the coronary artery under investigation. The angiographic image sequence is used to determine a volumetric flow rate for flow through the coronary artery under investigation, which is used to determine an index that represents a property of the microvascular tissue that is supplied with blood via the coronary artery under investigation.Type: ApplicationFiled: November 21, 2023Publication date: May 23, 2024Applicant: Pie Medical Imaging B.V.Inventors: Chris Bouwman, Dennis Koehn, Jean-Paul Aben
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Publication number: 20230309943Abstract: Methods and systems are provided for dynamically visualizing an object of interest that includes part of the vasculature of a patient, which employ a 3D model of the object to generate at least one roadmap that includes information that characterizes properties of the object (such as centerlines, contours, and an image mask. Reference location(s) corresponding to the roadmap(s) are determined for an interventional device used to treat the object. In an online phase, non-contrast-enhanced x-ray image data of the object are obtained and processed to determine location of the interventional device in the image data, and a particular roadmap is selected or accessed. The reference location corresponding to the particular roadmap and the determined location of interventional device are used to transform the particular roadmap. A visual representation of the transformed roadmap is overlaid on the image data for display.Type: ApplicationFiled: June 7, 2023Publication date: October 5, 2023Applicant: Pie Medical Imaging B.V.Inventors: Theo van Walsum, Hua Ma, Jean-Paul Aben, Dennis Koehn
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Patent number: 11707242Abstract: Methods are provided for dynamically visualizing information in image data of an object of interest of a patient, which include an offline phase and an online phase. In the offline phase, first image data of the object of interest acquired with a contrast agent is obtained with an interventional device is present in the first image data. The first image data is used to generate a plurality of roadmaps of the object of interest. A plurality of reference locations of the device in the first image data is determined, wherein the plurality of reference locations correspond to the plurality of roadmaps. In the online phase, live image data of the object of interest acquired without a contrast agent is obtained with the device present in the live image data, and a roadmap is selected from the plurality of roadmaps. A location of the device in the live image data is determined.Type: GrantFiled: January 10, 2020Date of Patent: July 25, 2023Assignee: Pie Medical Imaging B.V.Inventors: Theo van Walsum, Hua Ma, Jean-Paul Aben, Dennis Koehn
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Patent number: 11694339Abstract: A method for quantitative flow analysis of a fluid flowing in a conduit from a sequence of consecutive image frames of such a conduit, where such image frames are timely separated by a certain time interval, the method comprising: a) selecting a start image frame and an end image frame from the sequence either automatically or upon user input; b) determining a centerline of the conduit in the start image frame; c) determining a centerline of the conduit in the end image frame; d) selecting a common start point on the centerline of the start image frame and on the centerline of the end image frame either automatically or upon user input; e) selecting an end point on the centerline of the start image frame; f) selecting an end point on the centerline of the end image frame; g) calculating centerline distance between the start point and the end point of the start image frame; h) calculating centerline distance between the start point and the end point of the end image frame; and i) calculating a local flow veType: GrantFiled: May 4, 2018Date of Patent: July 4, 2023Assignee: Pie Medical Imaging B.V.Inventors: Ron Schormans, Jean-Paul Aben, Dennis Koehn
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Publication number: 20220164950Abstract: Method and systems are described that create a 3D reconstruction of a vessel of interest that represents a subset of a coronary tree that includes a lesion; calculate at least one of pressure parameters or anatomical parameters based at least in part on a portion of the 3D reconstruction that includes the lesion; calculate a wall shear stress (WSS) descriptor, based on the 3D reconstruction, for a segment of a surface of the vessel that includes the lesion, wherein the WSS descriptor includes information regarding an amount of variation in contraction or expansion applied at surface elements within the segment during at least a portion of a cardiac cycle; and calculate a myocardial infarction (MI) index based on the WSS descriptor and the at least one of the pressure or anatomical parameters, the MI index representing a likelihood that the lesion will result in an MI.Type: ApplicationFiled: November 19, 2021Publication date: May 26, 2022Inventors: Jean-Paul Michel Maria Aben, Carlos Collet Bortone, Dennis Koehn
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Publication number: 20210338088Abstract: Computer-implemented methods and systems are provided for quantitative hemodynamic flow analysis, which involves retrieving patient specific image data. A 3D reconstruction of a vessel of interest can be created from the patient specific image data. Geometric information can be extracted from the 3D reconstruction. A lesion position can be determined. Patient specific data can be obtained. Hemodynamic results can be calculated based on the geometric information, the lesion position and the patient specific data.Type: ApplicationFiled: July 2, 2021Publication date: November 4, 2021Applicant: PIE MEDICAL IMAGING B.V.Inventors: Chris Bouwman, Dennis Koehn, Jean-Paul Aben
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Patent number: 11083377Abstract: Computer-implemented methods and systems are provided for quantitative hemodynamic flow analysis, which involves retrieving patient specific image data. A 3D reconstruction of a vessel of interest can be created from the patient specific image data. Geometric information can be extracted from the 3D reconstruction. A lesion position can be determined. Patient specific data can be obtained. Hemodynamic results can be calculated based on the geometric information, the lesion position and the patient specific data.Type: GrantFiled: June 12, 2019Date of Patent: August 10, 2021Assignee: Pie Medical Imaging B.V.Inventors: Chris Bouwman, Dennis Koehn, Jean-Paul Aben
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Patent number: 10733792Abstract: Systems and methods provide guidance for selection of projection perspectives to utilize to obtain complementary combinations of projection images of an object. The systems and methods provide a bi-dimensional first image of the object which has been obtained from a first perspective. A map of values associated with different candidate perspectives relative to the first perspective is determined, wherein the value associated with a given candidate perspective is determined from at least one parameter indicative of a degree to which the given candidate perspective complements the first perspective and at least one weighting parameter. The map can be displayed or evaluated to select at least one candidate perspective to utilize to acquire or obtain a combination of complementary projection images.Type: GrantFiled: January 24, 2019Date of Patent: August 4, 2020Assignee: Pie Medical Imaging B.V.Inventors: Jean-Paul Aben, Tom van Neerven, Rianne Reinartz, Dennis Koehn
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Publication number: 20200222018Abstract: Methods are provided for dynamically visualizing information in image data of an object of interest of a patient, which include an offline phase and an online phase. In the offline phase, first image data of the object of interest acquired with a contrast agent is obtained with an interventional device is present in the first image data. The first image data is used to generate a plurality of roadmaps of the object of interest. A plurality of reference locations of the device in the first image data is determined, wherein the plurality of reference locations correspond to the plurality of roadmaps. In the online phase, live image data of the object of interest acquired without a contrast agent is obtained with the device present in the live image data, and a roadmap is selected from the plurality of roadmaps. A location of the device in the live image data is determined.Type: ApplicationFiled: January 10, 2020Publication date: July 16, 2020Applicant: Pie Medical Imaging B.V.Inventors: Theo van Walsum, Hua Ma, Jean-Paul Aben, Dennis Koehn
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Publication number: 20190380593Abstract: Computer-implemented methods and systems are provided for quantitative hemodynamic flow analysis, which involves retrieving patient specific image data. A 3D reconstruction of a vessel of interest can be created from the patient specific image data. Geometric information can be extracted from the 3D reconstruction. A lesion position can be determined. Patient specific data can be obtained. Hemodynamic results can be calculated based on the geometric information, the lesion position and the patient specific data.Type: ApplicationFiled: June 12, 2019Publication date: December 19, 2019Applicant: Pie Medical Imaging B.V.Inventors: Chris Bouwman, Dennis Koehn, Jean-Paul Aben
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Patent number: 10360674Abstract: A method is provided for flow analysis in a target volume of a moving organ, which involves a sequence of first volumetric image data sets that include structural information and three-directional velocity information of the target volume and a sequence of second volumetric image data sets that include structural information of the target volume. The method involves tracking a feature of interest within the sequence of the second volumetric data sets, determining time varying spatial orientation of a plane containing the feature of interest in the sequence of the first volumetric image data sets by transferring the plane from the second volumetric image data sets to the first volumetric image data sets, reformatting the three-directional velocity information into one-directional velocity information on the plane, and performing bi-dimensional quantitative flow analysis using the one-directional velocity information. A corresponding apparatus and computer program are also disclosed and claimed.Type: GrantFiled: April 6, 2016Date of Patent: July 23, 2019Assignee: PIE MEDICAL IMAGING B.V.Inventors: Enrico Contini, Jean-Paul Aben, Dennis Koehn, Rianne Reinartz
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Publication number: 20190156554Abstract: Systems and methods provide guidance for selection of projection perspectives to utilize to obtain complementary combinations of projection images of an object. The systems and methods provide a bi-dimensional first image of the object which has been obtained from a first perspective. A map of values associated with different candidate perspectives relative to the first perspective is determined, wherein the value associated with a given candidate perspective is determined from at least one parameter indicative of a degree to which the given candidate perspective complements the first perspective and at least one weighting parameter. The map can be displayed or evaluated to select at least one candidate perspective to utilize to acquire or obtain a combination of complementary projection images.Type: ApplicationFiled: January 24, 2019Publication date: May 23, 2019Applicant: Pie Medical Imaging B.V.Inventors: Jean-Paul Aben, Tom van Neerven, Rianne Reinartz, Dennis Koehn
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Publication number: 20180330507Abstract: A method for quantitative flow analysis of a fluid flowing in a conduit from a sequence of consecutive image frames of such a conduit, where such image frames are timely separated by a certain time interval, the method comprising: a) selecting a start image frame and an end image frame from the sequence either automatically or upon user input; b) determining a centerline of the conduit in the start image frame; c) determining a centerline of the conduit in the end image frame; d) selecting a common start point on the centerline of the start image frame and on the centerline of the end image frame either automatically or upon user input; e) selecting an end point on the centerline of the start image frame; f) selecting an end point on the centerline of the end image frame; g) calculating centerline distance between the start point and the end point of the start image frame; h) calculating centerline distance between the start point and the end point of the end image frame; and i) calculating a local flow veType: ApplicationFiled: May 4, 2018Publication date: November 15, 2018Applicant: Pie Medical Imaging B.V.Inventors: Ron Schormans, Jean-Paul Aben, Dennis Koehn
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Publication number: 20160314581Abstract: A method for performing flow analysis in a target volume of a moving organ from sequences of a first and a second magnetic resonance volumetric image data sets of such organ, which data sets are timely separated by a certain time interval, wherein the first volumetric image data sets comprise structural information and three-directional velocity information of the target volume and the second volumetric image data sets comprises structural information of the target volume, the method comprising the following steps: a) determining at least one feature of interest in at least one volume data set of the sequence of second volumetric image data sets; b) tracking the feature of interest within one or more volume data sets of the sequence of the second volumetric data sets; c) determining the spatial orientation over time of a plane containing the feature of interest in the sequence of the second volumetric data sets; d) determining the spatial orientation over time of the plane containing the feature of interesType: ApplicationFiled: April 6, 2016Publication date: October 27, 2016Applicant: PIE MEDICAL IMAGING B.V.Inventors: Enrico Contini, Jean-Paul Aben, Dennis Koehn, Rianne Reinartz
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Patent number: 4619223Abstract: A portable corral for cattle and the like is provided and consists of a trailer having a first opening in one side frame and a second opening in the rear frame so that the cattle may enter and egress therefrom. A solid side cover is affixed to other side frame of the trailer to reduce wind thereof. A series of panel frames are carried by the trailer and are assembled to the trailer and linked with one another to constitute the corral. Some of the panel frames are pivotally secured to the trailer for moment between retracted positions against the trailer sides and selected extended positions.Type: GrantFiled: April 29, 1985Date of Patent: October 28, 1986Inventor: Dennis Koehn