Abstract: The present invention provides a recombinant fusion protein containing a first extracellular Ig-like domain of a signal-regulator protein alpha (SIRP?), linked to an Fc fragment of a human IgG1. The present invention also provides a polynucleotide encoding the recombinant fusion protein, an expression vector containing the polynucleotide, a method for producing the recombinant protein and a method for treating a disease caused by over expression of CD47.

Abstract: The present invention provides a recombinant fusion protein containing a first extracellular Ig-like domain of a signal-regulator protein alpha (SIRP?), linked to an Fc fragment of a human IgG1. The present invention also provides a polynucleotide encoding the recombinant fusion protein, an expression vector containing the polynucleotide, a method for producing the recombinant protein and a method for treating a disease caused by over expression of CD47.

Abstract: The present invention provides a recombinant fusion protein containing a first extracellular Ig-like domain of a signal-regulator protein alpha (SIRP?), linked to an Fc fragment of a human IgG1. The present invention also provides a polynucleotide encoding the recombinant fusion protein, an expression vector containing the polynucleotide, a method for producing the recombinant protein and a method for treating a disease caused by over expression of CD47.

Abstract: A heavy current reed switch contact structure comprises at least one set of elastic reed electrode (11, 12) or at least one fixed electrode (12) and an elastic reed electrode (11). The reed electrode (11, 12) is made of a conductive material. Contacts (13, 14) are arranged on opposing surfaces of mutually overlapping ends. A side of the end having the contacts is disposed with an arc discharge device (16, 162). The reed switch employs a specially designed contact structure, and the arc discharge structure device is additionally disposed on the basis of a traditional switch contact structure. As a result, the reed switch quickly transfers to the contact arc discharge structure device an instantons arc generated upon switching the switch contact, thereby easing burnout resulting from an arc on the contact surfaces of the contacts, enabling the contacts to be less prone to being adhered together, and considerably increasing a bearing current and a switching capacity of the reed switch.

Abstract: A heavy current reed switch contact structure comprises at least one set of elastic reed electrode (11, 12) or at least one fixed electrode (12) and an elastic reed electrode (11). The reed electrode (11, 12) is made of a conductive material. Contacts (13, 14) are arranged on opposing surfaces of mutually overlapping ends. A side of the end having the contacts is disposed with an arc discharge device (16, 162). The reed switch employs a specially designed contact structure, and the arc discharge structure device is additionally disposed on the basis of a traditional switch contact structure. As a result, the reed switch quickly transfers to the contact arc discharge structure device an instantons arc generated upon switching the switch contact, thereby easing burnout resulting from an arc on the contact surfaces of the contacts, enabling the contacts to be less prone to being adhered together, and considerably increasing a bearing current and a switching capacity of the reed switch.

Abstract: A magnetic reed switch, including: an insulating casing, magnetic reeds, and at least one flexible element. The insulating casing is a hollow structure. The magnetic reeds are disposed inside and at two ends of the insulating casing, respectively. Ends of the magnetic reeds overlap. The at least one flexible element is an electrically conductive material and is disposed on at least one magnetic reed. The at least one flexible element is connected in parallel to two ends of the magnetic reeds.

Abstract: The present invention provides a recombinant fusion protein containing a first extracellular Ig-like domain of a signal-regulator protein alpha (SIRP?), linked to an Fc fragment of a human IgG1. The present invention also provides a polynucleotide encoding the recombinant fusion protein, an expression vector containing the polynucleotide, a method for producing the recombinant protein and a method for treating a disease caused by over expression of CD47.

Abstract: A magnetic reed switch, including: an insulating casing, magnetic reeds, and at least one flexible element. The insulating casing is a hollow structure. The magnetic reeds are disposed inside and at two ends of the insulating casing, respectively. Ends of the magnetic reeds overlap. The at least one flexible element is an electrically conductive material and is disposed on at least one magnetic reed. The at least one flexible element is connected in parallel to two ends of the magnetic reeds.

Abstract: A recombinant bi-functional fusion protein, comprising an Ig region of an extracellular domain of a signal-regulator protein (SIRP), linked via a Fc fragment of an Ig, to an Ig region of an extracellular domain of VEGFR, wherein the protein can bind to CD47 and VEGF simultaneously, blocking the binding of CD47 with the SIRP on the cell surface of macrophages to stimulate the phagocytosis of tumor cells by macrophages, and inhibiting the growth of vascular endothelial cells induced by VEGF. The present application also provides a nucleic acid molecule encoding the recombinant bi-functional fusion protein and an expression vector expressing the protein, a method for producing the protein and a method for treating a disease over-expressing CD47 or VEGF.