Abstract: A transintimal recanalization device comprising a guide tube (2) having a bend (C) in its length, a flexible needle (1) having a bevelled end (A) and a bend (C') in its length and located in said tube (2), wherein said needle (1) is movable from a covered position wherein said bevelled end (A) is within the tube (2) to an uncovered position in which said bevelled end (A) is exposed, and wherein said bends (C, C') match thereby orientating the bevelled end with respect to the tube (2). The device finds particular application in breaking through a vessel intima into a targeted distal vessel lumen in order to allow the passage of a guidewire.