Patents by Inventor Derek K. Douglas

Derek K. Douglas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100009451
    Abstract: The present invention provides methods modified oligonucleotides and methods of using the modified oligonucleotides for silencing nucleic acids, wherein the nonspecific effects of nucleic acid silencing are reduced.
    Type: Application
    Filed: May 29, 2009
    Publication date: January 14, 2010
    Applicant: SIGMA ALDRICH COMPANY
    Inventors: Erik R. Eastlund, Greg D. Davis, Derek K. Douglas, David K. Stone
  • Patent number: 7214484
    Abstract: Methods and compositions for extracting nucleic acids from a biological sample are provided. The extraction compositions contain a protease enzyme such as proteinase K at alkaline pH with little or no surfactant present. Extraction can be efficiently performed in 60 minutes or less at room temperature for certain mammalian tissue samples and at elevated temperatures for certain plant tissues.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: May 8, 2007
    Assignee: Sigma-Aldrich Co.
    Inventors: Scott A. Weber, Derek K. Douglas, Carol Kreader
  • Publication number: 20040115658
    Abstract: Methods and compositions for extracting nucleic acids from a biological sample are provided. The extraction compositions contain a protease enzyme such as proteinase K at alkaline pH with little or no surfactant present. Extraction can be efficiently performed in 60 minutes or less at room temperature for certain mammalian tissue samples and at elevated temperatures for certain plant tissues.
    Type: Application
    Filed: December 17, 2002
    Publication date: June 17, 2004
    Inventors: Scott A. Weber, Derek K. Douglas, Carol Kreader