Patents by Inventor Derek Morris
Derek Morris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11993793Abstract: The present disclosure encompasses engineered meganucleases that bind and cleave recognition sequences within a dystrophin gene. The present disclosure also encompasses methods of using such engineered meganucleases to make genetically modified cells. Further, the disclosure encompasses pharmaceutical compositions comprising engineered meganuclease proteins, or polynucleotides encoding engineered meganucleases of the disclosure, and the use of such compositions for the modification of a dystrophin gene in a subject, or for treatment of Duchenne Muscular Dystrophy.Type: GrantFiled: July 27, 2023Date of Patent: May 28, 2024Assignee: Precision BioSciences, Inc.Inventors: Gary Owens, Janel Lape, James Jefferson Smith, John Morris, Caitlin Turner, Whitney Lewis, Derek Jantz
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Publication number: 20240148284Abstract: Machine learning in an artificial pancreas is described. An artificial pancreas system may include a wearable glucose monitoring device, an insulin delivery system, and a computing device. Broadly speaking, the wearable glucose monitoring device provides glucose measurements of a person continuously. The artificial pancreas algorithm, which may be implemented at the computing device, determines doses of insulin to deliver to the person based on a variety of aspects for the purpose of maintaining the person's glucose within a target range, as indicated by those glucose measurements. The insulin delivery system then delivers those determined doses to the person. As the artificial pancreas algorithm determines insulin doses for the person over time and effectiveness of the insulin doses to maintain the person's glucose level in the target range is observed, an underlying model of the artificial pancreas algorithm may be updated to better determine insulin doses.Type: ApplicationFiled: November 28, 2023Publication date: May 9, 2024Inventors: Derek James Escobar, Naresh C. Bhavaraju, Gary A. Morris, Jorge Valdes
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Patent number: 11976498Abstract: A container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching assemblies. The latching assembly may comprise a latch body, a locking member, a biasing member, and an activating member. Additional features of the container may include handles and strength increasing features. The base and lid may also feature attachment points for various accessories. A carry strap may attach to the base of the container to allow a user to lift and carry the container. The container may also have a wheels attached to the bottom portion and/or across the bottom portion to one side of the sidewall structure. In addition, in exemplary containers with wheels, a pull handle may be attached to a side opposite the wheels. The lid may include a lid support member that can act as a molle board to releasably secure items to the lid support member while also providing structural support to the lid.Type: GrantFiled: December 16, 2020Date of Patent: May 7, 2024Assignee: YETI Coolers, LLCInventors: Roy Joseph Seiders, Steve Charles Nichols, Kyle Ellison, Andy Bondhus, Tobias Hotchkiss, Liza Morris, Dennis Zuck, Ryan Nixon, Mark Carlson Rane, Walter T. Blanchard, Nicholas James Lombardi, Dustin Bullock, Michael Christopher Cieszko, Derek G. Sullivan
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Publication number: 20240141311Abstract: Disclosed herein are recombinant meganucleases engineered to bind and cleave a recognition sequence in the mitochondrial DNA (mtDNA) of a eukaryotic cell, such as a plant cell. The disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells, and to a population of genetically-modified eukaryotic cells wherein the mtDNA has been having modified or edited.Type: ApplicationFiled: April 22, 2022Publication date: May 2, 2024Applicant: North Carolina State UniversityInventors: Ralph Dewey, Derek Jantz, James Jefferson Smith, Ginger H. Tomberlin, John Morris, Anna Matthiadis, Wendy Shoop
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Patent number: 11970313Abstract: An insulating container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching devices, in the closed configuration. In some examples, the insulating container further includes a pull handle assembly with a telescopic three-stage arm configuration defined by a stowed configuration, a partially extended configuration, and a fully extended configuration. In other examples, the insulating container further includes a wheel assembly with a pair of wheels mounted with one or two axles, and further including a wheel grommet for absorbing shock and cushioning the axle. In still other examples, the insulating container further includes a drain plug assembly on the rear sidewall adjacent to the bottom portion of the base, the drain plug assembly comprising a main tube that cooperatively engages with an outer tube with a plurality of ratchet teeth that engage one or more ratchet keys on the main tube.Type: GrantFiled: May 12, 2022Date of Patent: April 30, 2024Assignee: YETI Coolers, LLCInventors: Liza Morris, Andrew J. Winterhalter, Robert Secker, Dustin R. Bullock, Elizabeth Ruchte, Ryan Nixon, Derek G. Sullivan, John Loudenslager, John Fritz, Erik Steven Larson, Lance Harrison, Michael Christopher Cieszko
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Publication number: 20240128071Abstract: An apparatus is disclosed comprising a first device for generating aerosol, smoke or vapour from one or more regions of a target, an inlet conduit to an ion analyser or mass spectrometer, the inlet conduit having an inlet through which the aerosol, smoke or vapour passes, and a Venturi pump arrangement arranged and adapted to direct the aerosol, smoke or vapour towards the inlet.Type: ApplicationFiled: October 20, 2023Publication date: April 18, 2024Inventors: Zoltán TAKÁTS, Júlia BALOG, Steven Derek PRINGLE, Tamás KARANCSI, Michael Raymond MORRIS, Lajos GÖDÖRHÁZY, Dániel SZALAY, Dániel SIMON
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Publication number: 20240109564Abstract: A method is provided that can include activating at least two wireless communication channels in parallel, between a first wireless transceiver and a second wireless transceiver. Each of the at least two wireless communication channels can operate at a different radio carrier frequency, and the first wireless transceiver may be part of a first vehicle. The method can also include transmitting, by the first wireless transceiver, common information in parallel on the at least two wireless communication channels to the second wireless transceiver and deactivating the at least two wireless communication channels.Type: ApplicationFiled: December 12, 2023Publication date: April 4, 2024Inventors: Padam Dhoj Swar, Carl L. Haas, Danial Rice, Rebecca W. Dreasher, Adam Hausmann, Matthew Steven Vrba, Edward J. Kuchar, James Lucas, Andrew Ryan Staats, Jerrid D. Chapman, Jeffrey D. Kernwein, Janmejay Tripathy, Stephen Craven, Tania Lindsley, Derek K. Woo, Ann K. Grimm, Scott Sollars, Phillip A. Burgart, James Allen Oswald, Shannon K. Struttmann, Stuart J. Barr, Keith Smith, Francois P. Pretorius, Craig K. Green, Kendrick Gawne, Irwin Morris, Joseph W. Gorman, Srivallidevi Muthusami, Mahesh Babu Natarajan, Jeremiah Dirnberger, Adam Franco
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Publication number: 20230256672Abstract: A platform form an apparatus for printing a 3D model comprises a base and a print layer. The base has a first side where the first side of the base has a first surface roughness thereon. The print layer is coupled first side of the base and includes a surface. The surface of the print layer is distal from the base and has a second surface roughness which is greater than the first surface roughness so as to promote adhesion of the 3D model being printed on the platform.Type: ApplicationFiled: February 13, 2023Publication date: August 17, 2023Applicant: Lung Biotechnology PBCInventors: Mohammadali Safavieh, Akarsh Sivaprasad, Mora Melican, Masoud Modaresifar, Datta Saravana Kalyan Kumar Vydiam, Barbara Nsiah, Derek Morris, Luis Alvarez
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Publication number: 20230183652Abstract: A printable composition for the manufacture of cell-receiving scaffolds comprising about 0.3 wt % to about 3.0 wt % of one or more collagens; about 5.0 wt % to about 40.0 wt % of one or more monomers; about 0.5 wt % to about 2.0 wt % of a photo initiator; and 0 wt % to about 75 wt % of a vehicle comprising a protic solvent, by weight of the printable composition; wherein the printable composition has a resolution of about 100 microns or less when printed, a photo speed (Dp/Ec) of about 0.1-5 mm (Dp) and about 10-100 mJ/cm2 (Ec) when printed, and a green strength of at least about 5 kPa after drying. The present technology further includes methods of manufacturing a three-dimensional cell-receiving scaffold using the printable composition.Type: ApplicationFiled: January 31, 2023Publication date: June 15, 2023Applicant: Lung Biotechnology PBCInventors: Pingyong Xu, Luis Alvarez, Derek Morris, Iman Yazdi
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Publication number: 20230131073Abstract: A method of printing a hydrogel scaffold is provided which includes providing a container containing an ink and a liquid that is immiscible with the ink; applying light from a light source to the ink to form a portion of the hydrogel scaffold; and from a light source one or more additional times to produce one or more additional portions of the hydrogel scaffold.Type: ApplicationFiled: October 21, 2022Publication date: April 27, 2023Applicant: Lung Biotechnology PBCInventors: Daniel Backman, Mohammadali Safavieh, Aman Kaur, Derek Morris, Luis M. Alvarez
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Patent number: 11597915Abstract: A printable composition for the manufacture of cell-receiving scaffolds comprising about 0.3 wt % to about 3.0 wt % of one or more collagens; about 5.0 wt % to about 40.0 wt % of one or more monomers; about 0.5 wt % to about 2.0 wt % of a photo initiator; and 0 wt % to about 75 wt % of a vehicle comprising a protic solvent, by weight of the printable composition; wherein the printable composition has a resolution of about 100 microns or less when printed, a photo speed (Dp/Ec) of about 0.1-5 mm (Dp) and about 10-100 mJ/cm2 (Ec) when printed, and a green strength of at least about 5 kPa after drying. The present technology further includes methods of manufacturing a three-dimensional cell-receiving scaffold using the printable composition.Type: GrantFiled: August 1, 2019Date of Patent: March 7, 2023Assignee: Lung Biotechnology PBCInventors: Pingyong Xu, Luis Alvarez, Derek Morris, Iman Yazdi
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Publication number: 20220355541Abstract: Embodiments of the present disclosure include methods of simultaneously manufacturing two or more hydrogel constructs (e.g., tubular hydrogel constructs). In some embodiments, the method comprises one or more of the following steps: providing a vat comprising a bio-ink composition containing one or more monomers and/or one or more polymers; applying electromagnetic radiation from an electromagnetic radiation source to cure a layer of the hydrogel constructs (e.g., tubular hydrogel constructs); and applying electromagnetic radiation from the electromagnetic radiation source one or more additional times to produce one or more additional layers of the hydrogel constructs (e.g., tubular hydrogel constructs).Type: ApplicationFiled: May 6, 2022Publication date: November 10, 2022Applicant: Lung Biotechnology PBCInventors: Mora Carolynne Melican, Lara Murcin, Richmon Lin, Derek Morris, Barbara Nsiah, Lius Alvarez, Mohammadali Safavieh
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Publication number: 20220356433Abstract: The systems and methods of the present disclosure can be used to generate systems and models that are physiologically relevant to the human and animal system. These physiological conditions can be designed to mimic the actual human condition for cell differentiation and proliferation. The system and methods of this present disclosure allow the formation of an appropriate biomaterial to mimic that which exists in a human or animal scaffold. Utilizing 3D printing technology, a hydrogel scaffold can be printed at various resolution very close to human physiological geometry. Additionally, the architecture can be optimized for the selected application and appropriate cells can be seeded on the scaffold prior to testing.Type: ApplicationFiled: May 6, 2022Publication date: November 10, 2022Applicant: Lung Biotechnology PBCInventors: Masoud Modaresifar, Mohammadali Safavieh, Keerthana Prakash, Greg Hurst, Daniel E. Backman, Derek Morris, Akbar Khalilpour, Rebecca Duffy, Aman Kaur, Isabel Arias, Barbara Nsiah, Luis Alvarez
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Publication number: 20220354954Abstract: The present disclosure provides reinforced hydrogel structures, methods of reinforcing hydrogel structures, and methods of treating ischemic disorders using the reinforced hydrogel structures.Type: ApplicationFiled: May 6, 2022Publication date: November 10, 2022Applicant: Lung Biotechnology PBCInventors: Mora Carolynne Melican, Lara Murcin, Barbara Nsiah, Richmon Lin, Derek Morris, Lina Trigg, Luis Alvarez, Mohammadali Safavieh, Masoud Modaresifar, Kalyan Vydiam
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Publication number: 20220305395Abstract: A ride system includes a track and an overhung ride assembly. The overhung ride assembly includes a transport platform coupled to the track, a ride vehicle, and a heave system extending between the transport platform and the ride vehicle. The heave system is configured to heave the ride vehicle relative to the transport platform. The heave system includes an extendible tube defining a variable volume configured to store a gaseous fluid. The extendible tube is configured to extend in response to a lowering of the ride vehicle away from the transport platform by the heave system such that the gaseous fluid within the variable volume of the extendible tube provides a fluid force that biases the extendible tube toward a contracted configuration to assist the heave system with a lifting of the ride vehicle toward the transport platform.Type: ApplicationFiled: March 25, 2022Publication date: September 29, 2022Inventors: Sandor Kernacs, Derek Morris, Trent Bitton, Trent Deem, Raleigh Cornwell, Greg Rude, John Stapleton
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Publication number: 20220281178Abstract: An additive manufacturing device includes an output device and a controller. The output device is configured to receive at least one material to generate a component. The controller includes one or more processors configured to receive a model including a plurality of pixels representing the component, identify at least one pixel of the plurality of pixels corresponding to a first surface of the component, modify the model to adjust an exposure corresponding to the at least one pixel based on a target exposure, and control operation of the output device to cause the output device to generate the component based on the modified model.Type: ApplicationFiled: March 3, 2022Publication date: September 8, 2022Applicant: Lung Biotechnology PBCInventors: Greg Hurst, Masoud Modaresifar, Mohammadali Safavieh, Derek Morris, Luis Alvarez, Daniel Backman
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Publication number: 20220055289Abstract: Apparatus and method for forming a three-dimensional object. The apparatus includes a platform on which the three-dimensional object is formed. The apparatus includes an oxygen soluble liquid having a build surface. The build surface and the platform define a build region therebetween. The apparatus includes a photosensitive liquid disposed on the oxygen soluble liquid. The density of the oxygen soluble liquid is greater than the density of the photosensitive liquid. The apparatus includes an optically transparent member. The optically transparent member supports the oxygen soluble liquid. The apparatus includes a radiation source configured to irradiate the build region through the optically transparent member and the oxygen soluble liquid to form a solid polymer from the photosensitive liquid. The apparatus includes a controller configured to advance the platform away from the build surface.Type: ApplicationFiled: August 24, 2021Publication date: February 24, 2022Applicant: Lung Biotechnology PBCInventors: Mohammadali Safavieh, Daniel E. Backman, Kalyan Vydiam, Masoud Modaresifar, Lara A. Murcin, Luis Alvarez, Derek Morris, Akarsh Sivaprasad
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Patent number: 11208208Abstract: A system for synchronizing events has a first subsystem that detects, measures, or generates a first set of events and the first subsystem has a first clock for time-stamping each event detected, measured, or generated by the first subsystem. The system further has a second subsystem that detects, measures, or generates a second set of events and the second subsystem has a second clock not synchronized to the first clock. The second clock is for time-stamping events detected, measured, or generated by the second subsystem. The first set of events is related to the second set of events. The system further has a processor that correlates the first set of events with the second set of events to determine a value indicative of a temporal shift between a time of occurrence of the first set of events and a time of occurrence of the second set of events.Type: GrantFiled: October 17, 2018Date of Patent: December 28, 2021Assignee: Geocue Group, Inc.Inventors: Lewis N. Graham, Jr., Carl S. Riddell, Derek Morris
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Patent number: 10889373Abstract: A drone system has a camera mounted to a frame of a drone, the camera configured to acquire image data upon receipt of a signal from a flight controller and a precision location device configured for continuously obtaining location data. Additionally, the drone system has a computing device configured for receiving a signal indicating that an image has been acquired, the computing device configured for transmitting a signal to a precision location device indicating that an image has been acquired, and the precision location device is further configured to record event data associated with a time indicating when the image was acquired.Type: GrantFiled: March 1, 2018Date of Patent: January 12, 2021Assignee: GEOCUE GROUP, LLCInventors: Lewis Graham, Nancy Graham, Derek Morris, Carl Steven Riddell, Hai Quang Dinh
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Publication number: 20200040306Abstract: A printable composition for the manufacture of cell-receiving scaffolds comprising about 0.3 wt % to about 3.0 wt % of one or more collagens; about 5.0 wt % to about 40.0 wt % of one or more monomers; about 0.5 wt % to about 2.0 wt % of a photo initiator; and 0 wt % to about 75 wt % of a vehicle comprising a protic solvent, by weight of the printable composition; wherein the printable composition has a resolution of about 100 microns or less when printed, a photo speed (Dp/Ec) of about 0.1-5 mm (Dp) and about 10-100 mJ/cm2 (Ec) when printed, and a green strength of at least about 5 kPa after drying. The present technology further includes methods of manufacturing a three-dimensional cell-receiving scaffold using the printable composition.Type: ApplicationFiled: August 1, 2019Publication date: February 6, 2020Applicant: Lung Biotechnology PBCInventors: Pingyong Xu, Luis Alvarez, Derek Morris, Iman Yazdi