Patents by Inventor Deryk G. Jones

Deryk G. Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thyroid-derived chondrocyte-stimulating factor
    Patent number: 5374550
    Abstract: Thyroid-derived chondrocyte stimulating factor (TDCSF) is a high molecular weight complex (greater than 500 kd) of proteinaceous subunits which can be at least partially dissociated into active portions by 8M urea. TDCSF stimulates articular chondrocyte and synovial fibroblast growth under serum-free conditions. TDCSF is useful for the culture of chondrocytes and fibroblasts in vitro as a serum substitute; for developing cartilage implants in vitro; and for in vivo use in cartilage and bone defect repair and degenerative joint diseases. TDCSF is stabilized in the presence of reducing agents for disulfide bonds. Antibodies for and conjugates of TDCSF are also disclosed.
    Type: Grant
    Filed: November 12, 1993
    Date of Patent: December 20, 1994
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: R. Lane Smith, Deryk G. Jones
  • Thyroid-derived chondrocyte-stimulating factor
    Patent number: 5284830
    Abstract: Thyroid-derived chondrocyte stimulating factor (TDCSF) is a high molecular weight complex (greater than 500 kd) of proteinaceous subunits which can be at least partially dissociated into active portions by 8 M urea. TDCSF stimulates articular chondrocyte and synovial fibroblast growth under serum-free conditions. TDCSF is useful for the culture of chondrocytes and fibroblasts in vitro as a serum substitute; for developing cartilage implants in vitro; and for in vivo use in cartilage and bone defect repair and degenerative joint diseases. TDCSF is stabilized in the presence of reducing agents for disulfide bonds. Antibodies for and conjugates of TDCSF are also disclosed.
    Type: Grant
    Filed: February 13, 1991
    Date of Patent: February 8, 1994
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: R. Lane Smith, Deryk G. Jones