Abstract: The present invention provides methods and apparatus for endoluminally performing gastroplasty. In one variation, the apparatus comprises a sizing tube, and a steerable guide that may be reversibly disposed within the sizing tube. In another variation, the sizing tube and steerable guide are integrated into a single device. In one method of utilizing the apparatus, a pouch is endoluminally formed within a patient's stomach, thereby partitioning or reducing the stomach and restricting the flow of food therethrough. The pouch may form a Vertical Banded Gastroplasty or Magenstrasse and Mill in an endoluminal fashion. Advantageously, the sizing tube or steerable guide may be used to properly size the endoluminal pouch.

Abstract: A tissue collection apparatus is adapted for use in capturing and removing tissue through a hole in a body wall defining a body cavity. The apparatus includes an elongate flexible enclosure sized and configured to extend through the hole with a first end of the enclosure positioned within the body cavity and a second end of the enclosure positioned outside the body cavity. Portions of the distal end define opposing first and second edges which define an opening into the enclosure. A flap extends through the opening and distally of the apparatus to form a lip facilitating placement of tissue through the opening and into the enclosure. The coupling attaches a tension member to the enclosure along at least a point disposed not more distally than the flap.