Patents by Inventor Detlef Rohm

Detlef Rohm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human monoclonal anti-rhesus (D) antibodies and cell lines producing same
    Patent number: 5851524
    Abstract: The invention relates to 2 human monoclonal antibodies of sub-classes IgG1 and IgG3, against the Rhesus D antigen and to a pharmaceutical composition containing a mixture of the said antibodies, more particularly intended for the prophylaxis of the haemolytic disease of the newborn. The invention also relates to the heterohybridoma cell lines that produce these antibodies, which are filed with the "Deutsche Sammlung von Mikroorganismen und Zellkulturen" under accession numbers DSM AC 2039 and DSM AC 2040.
    Type: Grant
    Filed: February 10, 1997
    Date of Patent: December 22, 1998
    Assignees: Association pour l'Essor de la Transfusion Sanguine dans la Region du Nord, BIOTEST Pharma GmbH
    Inventors: Roland Beliard, Ulf Bethke, Dominique Bourel, Ahmed Bouzidi, Herve Broly, Peter Byrne, Magali Holuigue, Michael Kloft, Detlef Rohm
  • Manufacturing intravenous tolerable immunoglobulin-G preparation
    Patent number: 5164487
    Abstract: Method of manufacturing an intravenously tolerable immunoglobulin-G preparation that is free of aggregates, vasoactive substances and proteolytic enzymes and accordingly appropriate for all types of patients, especially immunosuppressed patients, from a starting material that contains immunoglobulin G but from which the coagulation factors have been removed. The starting material is treated with 0.4 to 1.5% by volume of octanoic acid and then chromatographed, especially on an ion or cation exchanger or hydrophobic matrix.
    Type: Grant
    Filed: March 15, 1991
    Date of Patent: November 17, 1992
    Assignee: Biotest Pharma GmbH
    Inventors: Norbert Kothe, Dieter Rudnick, Detlef Piechaczek, Herwald Klein, Detlef Rohm, Michael Kloft