Patents by Inventor Devin B. Lowe

Devin B. Lowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to Express, Purify, and Biotinylate Eukaryotic Cell-Derived Major Histocompatibility Complexes
    Publication number: 20210380661
    Abstract: The present invention includes compositions and methods of making and using a fusion protein comprising a peptide, a first flexible linker, a ?2-microglobulin domain, a second flexible linker, a soluble major histocompatibility complex (MHC) heavy chain and a peptide tag.
    Type: Application
    Filed: October 15, 2019
    Publication date: December 9, 2021
    Inventors: Devin B. Lowe, Amanda L. Wooster
  • Immunogenic tumor associated stromal cell antigen peptides and methods of their use
    Patent number: 9937250
    Abstract: Immunogenic peptides from tumor associated stromal cell antigens, including combinations of such peptides, are disclosed herein. In some examples the peptides are useful for methods of eliciting an immune response. In additional examples the peptides are useful for methods of treating cancer. Methods for decreasing vascularization of a tumor using a Protein Delta Homolog 1 (DLK1) protein or a nucleic acid encoding the protein are also disclosed.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: April 10, 2018
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Walter J. Storkus, Anamika Bose, Jennifer Lynn Taylor, Xi Zhao, Devin B. Lowe
  • IMMUNOGENIC TUMOR ASSOCIATED STROMAL CELL ANTIGEN PEPTIDES AND METHODS OF THEIR USE
    Publication number: 20160220651
    Abstract: Immunogenic peptides from tumor associated stromal cell antigens, including combinations of such peptides, are disclosed herein. In some examples the peptides are useful for methods of eliciting an immune response. In additional examples the peptides are useful for methods of treating cancer. Methods for decreasing vascularization of a tumor using a Protein Delta Homolog 1 (DLK1) protein or a nucleic acid encoding the protein are also disclosed.
    Type: Application
    Filed: April 19, 2016
    Publication date: August 4, 2016
    Applicant: University of Pittsburgh - Of the Commonwealth S ystem of Higher Education
    Inventors: Walter J. Storkus, Anamika Bose, Jennifer Lynn Taylor, Xi Zhao, Devin B. Lowe
  • Immunogenic tumor associated stromal cell antigen peptides and methods of their use
    Patent number: 9345770
    Abstract: Immunogenic peptides from tumor associated stromal cell antigens, including combinations of such peptides, are disclosed herein. In some examples the peptides are useful for methods of eliciting an immune response. In additional examples the peptides are useful for methods of treating cancer. Methods for decreasing vascularization of a tumor using a Protein Delta Homolog 1 (DLK1) protein or a nucleic acid encoding the protein are also disclosed.
    Type: Grant
    Filed: November 15, 2012
    Date of Patent: May 24, 2016
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Walter J. Storkus, Anamika Bose, Jennifer Lynn Taylor, Xi Zhao, Devin B. Lowe
  • IMMUNOGENIC TUMOR ASSOCIATED STROMAL CELL ANTIGEN PEPTIDES AND METHODS OF THEIR USE
    Publication number: 20140314758
    Abstract: Immunogenic peptides from tumor associated stromal cell antigens, including combinations of such peptides, are disclosed herein. In some examples the peptides are useful for methods of eliciting an immune response. In additional examples the peptides are useful for methods of treating cancer. Methods for decreasing vascularization of a tumor using a Protein Delta Homolog 1 (DLK1) protein or a nucleic acid encoding the protein are also disclosed.
    Type: Application
    Filed: November 15, 2012
    Publication date: October 23, 2014
    Applicant: University of Pittsburgh- Of the Commonwealth System of Higher Education
    Inventors: Walter J. Storkus, Anamika Bose, Jennifer Lynn Taylor, Xi Zhao, Devin B. Lowe