Abstract: The present invention is directed to a viscoelastic composition comprising an aqueous solution having a minimum of about 0.01% w/v and a maximum of about 20% w/v of a viscoelastic polymer based upon the total volume of the viscoelastic composition. Typically, the viscoelastic composition further contains tris[hydroxymethyl]aminomethane and a polyol (for example sorbitol). The present invention also includes methods of use of the new viscoelastic composition and a packaging device.

Abstract: The present invention is a novel viscoelastic composition or material that includes a suitable aqueous carrier and alginate. The novel viscoelastic composition has rheological properties consistent with a good dispersive viscoelastic and improved damping ability over commercial dispersive viscoelastics.

Abstract: A drug delivery device for placement in the eye includes a drug core comprising a pharmaceutically active agent, and a holder that holds the drug core. The holder is made of a material impermeable to passage of the active agent and includes an opening for passage of the pharmaceutically agent therethrough to eye tissue. The device includes a layer of material permeable to passage of the active agent. The device further includes a disc of impermeable material disposed between the drug core and the opening in the holder.

Abstract: Chemical erosion drug delivery systems are provided that allow sustained release of therapeutic agents within a treated area for a prolonged period of time.

Abstract: Chemical erosion controlled release drug delivery systems are provided that allow controlled release of sustained concentrations of therapeutic agents within a treated area for a prolonged period of time. The favorable solubility characteristics of the chemical erosion controlled release drug delivery systems are controlled through the hydrophobicity and load level of pharmaceutically active agent or drug. Such controlled solubility characteristics allow for manipulation of the drug release rates depending on the particular therapeutic use and the particular needs of the patient.

Abstract: The present invention is directed to an ophthalmic solution for soft contact lenses for controlled release of polyethers into an eye's tear film. Polyether components of the subject solution are released from the soft contact lens material matrix over long time periods to produce longer lasting wetting performance, improved lubricity, improved end-of-the-day comfort and reduced feeling of dryness from wearing contact lenses. The present invention also includes the use of cationic polyelectrolytes for controlling the swelling of hydrogel contact lenses typically caused by the absorption of high concentrations of polyethers.

Abstract: A process for the purification of a silicone oil or fluid using neat supercritical carbon dioxide or a supercritical carbon dioxide mixture extraction to produce vitreoretinal silicone tamponades. The subject process is an economical, highly effective, reproducible, contaminant-free method by which unreacted relatively low molecular weight cyclic siloxanes and oligomers are removed from relatively high molecular weight silicone oil or fluid.

Abstract: The present invention is directed to an ophthalmic solution for soft contact lenses for controlled release of polyethers into an eye's tear film. Polyether components of the subject ophthalmic solution are released from the soft contact lens material matrix over long time periods to produce longer lasting wetting performance, improved lubricity, improved end-of-the-day comfort and reduced feeling of dryness from wearing contact lenses.

Abstract: A process for the purification of a silicone oil or fluid using neat supercritical carbon dioxide or a supercritical carbon dioxide mixture extraction to produce vitreoretinal silicone tamponades. The subject process is an economical, highly effective, reproducible, contaminant-free method by which unreacted relatively low molecular weight cyclic siloxanes and oligomers are removed from relatively high molecular weight silicone oil or fluid.

Abstract: A method of making a lens, such as a contact lens with a colored pattern, involves providing a digitized image of the pattern, and transferring the digitized image to a printable image that is printed on a surface of the lens.

Abstract: The invention relates to methods for preparing a fiber, thread or yarn including a polymer blend of a predominantly atactic flexible polyolefin polymer having a high weight average molecular weight of at least about 100,000 and a heat of fusion of about 15 to 60 J/g with an isotactic polypropylene polymer, and forming the polymer blend into a fiber, thread or yarn, wherein the flexible polymer is present in an amount sufficient to increase the elasticity of the fiber, thread or yarn to inhibit substantial breakage thereof, for use in non-woven products. The invention also relates to the fiber, thread or yarn including the polymers, as well as non-woven products prepared therefrom. Moreover, the invention relates to composite articles including the fiber, thread or yarn in combination with adhesive compositions, and polymer blends used for such adhesive compositions.

Abstract: Multi-layer film products comprising an inner or core layer made from polyolefin polymers produced by polymerizing an .alpha.-olefin in the presence of a catalyst including: a pro-catalyst having a magnesium halide; an aluminum halide; a tetravalent titanium halide, ;an electron donor; and a silane having the formula R.sub.1 R.sub.2 Si(OR.sub.3)(OR.sub.4), wherein R.sub.1 and R.sub.2 are each an H, C.sub.1-6 alkyl, aryl, C.sub.5-12 cycloalkyl, each of which may be unsubstituted, mono- or di-substituted, and R.sub.3 and R.sub.4 are H, C.sub.1-6 alkyl, or a mono- or di-substituted C.sub.1-6 alkyl; and a co-catalyst comprising an organometallic compound, or reaction products of the pro-catalyst and the co-catalyst. The film products have excellent clarity, superior dart impact, resistance to tear and favorable sealibility characteristics.