Patents by Inventor Dhimant H. Desai

Dhimant H. Desai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200377497
    Abstract: Compositions for preventing or treating virus infections inhibit the biogenesis of cytoplasmic viral assembly compartment (cVAC). The preferred compounds are dihydroquinazolinones.
    Type: Application
    Filed: August 11, 2020
    Publication date: December 3, 2020
    Inventors: Nicholas J. Buchkovich, Linda M. Cruz, Dhimant H. Desai, Shantu Amin, Aron Lukacher, Saumya Maru
  • Patent number: 10781203
    Abstract: Compositions for preventing or treating virus infections inhibit the biogenesis of cytoplasmic viral assembly compartment (cVAC). The preferred compounds are dihydroquinazolinones.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: September 22, 2020
    Assignee: The Penn State Research Foundation
    Inventors: Nicholas J. Buchkovich, Linda M. Cruz, Dhimant H. Desai, Shantu Amin, Aron Lukacher, Saumya Maru
  • Publication number: 20190241553
    Abstract: Compositions for preventing or treating virus infections inhibit the biogenesis of cytoplasmic viral assembly compartment (cVAC). The preferred compounds are dihydroquinazolinones.
    Type: Application
    Filed: July 20, 2017
    Publication date: August 8, 2019
    Applicant: The Penn State Research Foundation
    Inventors: Nicholas J. Buchkovich, Linda M. Cruz, Dhimant H. Desai, Shantu Amin, Aron Lukacher, Saumya Maru
  • Patent number: 9918966
    Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: March 20, 2018
    Assignee: The Penn State Research Foundation
    Inventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
  • Publication number: 20160354344
    Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.
    Type: Application
    Filed: August 23, 2016
    Publication date: December 8, 2016
    Inventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
  • Patent number: 9439887
    Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: September 13, 2016
    Assignee: The Penn State Research Foundation
    Inventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
  • Publication number: 20150376124
    Abstract: Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.
    Type: Application
    Filed: June 30, 2015
    Publication date: December 31, 2015
    Inventors: Gavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai
  • Publication number: 20150265577
    Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.
    Type: Application
    Filed: June 9, 2015
    Publication date: September 24, 2015
    Inventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
  • Patent number: 9126910
    Abstract: Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: September 8, 2015
    Assignee: The Penn State Research Foundation
    Inventors: Gavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai
  • Patent number: 9126911
    Abstract: Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: September 8, 2015
    Assignee: The Penn State Research Foundation
    Inventors: Gavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai
  • Patent number: 9107947
    Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: August 18, 2015
    Assignee: The Penn State Research Foundation
    Inventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
  • Patent number: 9096505
    Abstract: Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: August 4, 2015
    Assignee: The Penn State Research Foundation
    Inventors: Gavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai
  • Publication number: 20140212475
    Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.
    Type: Application
    Filed: January 31, 2014
    Publication date: July 31, 2014
    Applicant: THE PENN STATE RESEARCH FOUNDATION
    Inventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
  • Publication number: 20130253052
    Abstract: Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.
    Type: Application
    Filed: March 5, 2013
    Publication date: September 26, 2013
    Applicant: The Penn State Research Foundation
    Inventors: Gavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai