Patents by Inventor Dhimant H. Desai
Dhimant H. Desai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200377497Abstract: Compositions for preventing or treating virus infections inhibit the biogenesis of cytoplasmic viral assembly compartment (cVAC). The preferred compounds are dihydroquinazolinones.Type: ApplicationFiled: August 11, 2020Publication date: December 3, 2020Inventors: Nicholas J. Buchkovich, Linda M. Cruz, Dhimant H. Desai, Shantu Amin, Aron Lukacher, Saumya Maru
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Patent number: 10781203Abstract: Compositions for preventing or treating virus infections inhibit the biogenesis of cytoplasmic viral assembly compartment (cVAC). The preferred compounds are dihydroquinazolinones.Type: GrantFiled: July 20, 2017Date of Patent: September 22, 2020Assignee: The Penn State Research FoundationInventors: Nicholas J. Buchkovich, Linda M. Cruz, Dhimant H. Desai, Shantu Amin, Aron Lukacher, Saumya Maru
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Publication number: 20190241553Abstract: Compositions for preventing or treating virus infections inhibit the biogenesis of cytoplasmic viral assembly compartment (cVAC). The preferred compounds are dihydroquinazolinones.Type: ApplicationFiled: July 20, 2017Publication date: August 8, 2019Applicant: The Penn State Research FoundationInventors: Nicholas J. Buchkovich, Linda M. Cruz, Dhimant H. Desai, Shantu Amin, Aron Lukacher, Saumya Maru
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Patent number: 9918966Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.Type: GrantFiled: August 23, 2016Date of Patent: March 20, 2018Assignee: The Penn State Research FoundationInventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
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Publication number: 20160354344Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.Type: ApplicationFiled: August 23, 2016Publication date: December 8, 2016Inventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
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Patent number: 9439887Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.Type: GrantFiled: June 9, 2015Date of Patent: September 13, 2016Assignee: The Penn State Research FoundationInventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
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Publication number: 20150376124Abstract: Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.Type: ApplicationFiled: June 30, 2015Publication date: December 31, 2015Inventors: Gavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai
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Publication number: 20150265577Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.Type: ApplicationFiled: June 9, 2015Publication date: September 24, 2015Inventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
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Patent number: 9126910Abstract: Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.Type: GrantFiled: March 5, 2013Date of Patent: September 8, 2015Assignee: The Penn State Research FoundationInventors: Gavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai
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Patent number: 9126911Abstract: Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.Type: GrantFiled: March 5, 2013Date of Patent: September 8, 2015Assignee: The Penn State Research FoundationInventors: Gavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai
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Patent number: 9107947Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.Type: GrantFiled: January 31, 2014Date of Patent: August 18, 2015Assignee: The Penn State Research FoundationInventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
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Patent number: 9096505Abstract: Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.Type: GrantFiled: March 5, 2013Date of Patent: August 4, 2015Assignee: The Penn State Research FoundationInventors: Gavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai
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Publication number: 20140212475Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.Type: ApplicationFiled: January 31, 2014Publication date: July 31, 2014Applicant: THE PENN STATE RESEARCH FOUNDATIONInventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Dhimant H. Desai, Shantu G. Amin
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Publication number: 20130253052Abstract: Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.Type: ApplicationFiled: March 5, 2013Publication date: September 26, 2013Applicant: The Penn State Research FoundationInventors: Gavin P. Robertson, Arati K. Sharma, Arun K. Sharma, Shantu G. Amin, Dhimant H. Desai