Abstract: A method for determining a dosage regimen for a drug. Resistance (R) and reactance (Xc) are measured by bioelectrical impedance analysis with an impedance plethysmograph. Personal characteristics of a subject are ascertained and recorded along with the measured values of R and Xc. A technique for generating equations which relate the measured values of R and Xc and selected personal characteristics to pharmacokinetic parameters such as volume of distribution (V), elimination rate constant (K), and clearance (CL) for a particular drug are provided. These equations are used with the measured values of R and Xc and certain personal characteristics to determine predictive values for the desired pharmacokinetic parameters. These predictive values are then used to determine an appropriate drug dosage regimen for the patient.

Abstract: An apparatus and its method of use are provided allowing lavage, sump and enteral feeding operations with only one intubation. The apparatus includes a first tube having two distinct passageways. One of these passageways completely contains a second, feeding tube during intubation. Once the first tube is in place in the patient, the second tube is extended from the first tube so as to enter the stomach. The extension of the second tube opens ports in the first passageway of the first tube, thereby allowing sump or lavage treatment with the second passageway of the first tube serving as an air vent. A constriction in the end of the first passageway engages a band on the proximal end of the second tube to keep the tubes together.