Patents by Inventor Diana Mechtcheriakova

Diana Mechtcheriakova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarker in Inflammatory Diseases
    Publication number: 20100029007
    Abstract: The use of CD1B, or CD1D, respectively as a target for a disorder selected from Systemic Lupus Erythematosus (SLE), Lupus Anticoagulant (LA) Rheumatoid Arthritis (RA) and Idiopathic Thrombocytopenic Purpura; and the use of CD1D as a target in a disorder which is Multiple Sclerosis (MS), e.g. as a biomarker; a method for preparing a diagnostic kit and a method for identifying agents that modulates a disorder which is mediated by elevated levels of CD1B, or CD1D, respectively, in case of CD1B, or CD1D, respectively selected from Systemic Lupus Erythematosus (SLE), Lupus Anticqagulant (LA) Rheumatoid Arthritis (RA) and Idiopathic Thrombocytopenic Purpura; and in case of CD1D a disorder which is Multiple Sclerosis (MS).
    Type: Application
    Filed: October 10, 2007
    Publication date: February 4, 2010
    Inventors: Thomas Baumruken, Andreas Billich, Diana Mechtcheriakova, Alexander Wlachos
  • USE OF EDG RECEPTOR BINDING AGENTS IN CANCER
    Publication number: 20090209495
    Abstract: Provided is a method for treating solid tumors, e.g. tumor invasiveness, and particularly inhibiting or controlling deregulated angiogenesis, using a sphingosine-1-phosphate receptor agonist, optionally in combination with a chemotherapeutic agent. The invention also comprises a combination of a sphingosine-1-phosphate receptor agonist with a chemotherapeutic agent.
    Type: Application
    Filed: April 9, 2009
    Publication date: August 20, 2009
    Inventors: Thomas Baumruker, Volker Brinkmann, Kenneth Richard La Montagne, Peter T. Lassota, Diana Mechtcheriakova, Jeanette Marjorie Wood
  • Fluorescent Labeled Sphingosines
    Publication number: 20080318255
    Abstract: The present invention relates to a method (assay) for determining the activity of an enzyme selected from the group consisting of a sphingosine kinase and a phosphatase involved in the sphingolipid pathway by use of a labeled sphingosine.
    Type: Application
    Filed: September 28, 2004
    Publication date: December 25, 2008
    Inventors: Andreas Billich, Peter Ettmayer, Diana Mechtcheriakova, Peter Nussbaumer, Alexander Wlachos
  • BIOMARKER IN INFLAMMATORY DISEASES
    Publication number: 20080145883
    Abstract: The use of SPP2 as a target in inflammatory responses, e.g. as a biomarker, e.g. for immune disorders associated with inflammation, such as psoriasis; diagnostic kits comprising means for determining the level of SPP2 and a method for identifying agents that modulates SPP2 activity.
    Type: Application
    Filed: October 3, 2007
    Publication date: June 19, 2008
    Inventors: Thomas Baumruker, Andreas Billich, Diana Mechtcheriakova, Alexander Wlachos
  • Use of edg receptor binding agents in cancer
    Publication number: 20050215531
    Abstract: Provided is a method for treating solid tumors, e.g. tumor invasiveness, and particularly inhibiting or controlling deregulated angiogenesis, using a sphingosine-1-phosphate receptor agonist, optionally in combination with a chemotherapeutic agent. The invention also comprises a combination of a sphingosine-1-phosphate receptor agonist with a chemotherapeutic agent.
    Type: Application
    Filed: May 15, 2003
    Publication date: September 29, 2005
    Inventors: Thomas Baumruker, Volker Brinkmann, Kenneth La Montagne, Peter Lassota, Diana Mechtcheriakova, Jean Wood