Patents by Inventor Diane E. Taylor

Diane E. Taylor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of oligosaccharides, glycolipids, and glycoproteins using bacterial glycosyltransferases
    Patent number: 7524655
    Abstract: This invention provides nucleic acid and amino acid sequences of fucosyltransferases from Helicobactor pylori. The invention also provides methods to use the fucosyltransferases to synthesize oligosaccharides, glycoproteins, and glycolipids.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: April 28, 2009
    Assignees: Neose Technologies, Inc., Governors of the University of Alberta
    Inventors: Karl F. Johnson, Daniel James Bezila, Diane E. Taylor, Joanne Simala-Grant, David Rasko
  • ?1,3-fucosyltransferase
    Patent number: 7166449
    Abstract: A bacterial ?1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing ?1,3-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, and siayl Lewis X, which are structurally similar to certain tumor-associated carbohy-drate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors. In addition the polypeptide of the invention can be used to develop diagnostic and research assays to determine the presence of H. pylori in human specimens.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: January 23, 2007
    Assignee: The Governors of the University of Alberta
    Inventors: Diane E. Taylor, Zhongming Ge
  • ?1,3-fucosyltransferase
    Patent number: 7029891
    Abstract: A bacterial ?1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing ?1,3-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, and siayl Lewis X, which are structurally similar to certain tumor-associated carbohydrate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors. In addition the polypeptide of the invention can be used to develop diagnostic and research assays to determine the presence of H. pylori in human specimens.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: April 18, 2006
    Assignee: The Governors of the University of Alberta
    Inventors: Diane E. Taylor, Zhongming Ge
  • ?-1,3 fucosyltransferases and expression systems for making and expressing them
    Patent number: 6962806
    Abstract: A bacterial ?1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing ?1,3-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, and siayl Lewis X, which are structurally similar to certain tumor-associated carbohydrate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors. In addition the polypeptide of the invention can be used to develop diagnostic and research assays to determine the presence of H. pylori in human specimens.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: November 8, 2005
    Assignee: The Governers of the University of Alberta
    Inventors: Diane E. Taylor, Zhongming Ge
  • Alpha-1,3 fucosyltransferases and expression systems for making and expressing them
    Publication number: 20030166211
    Abstract: A bacterial &agr;1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing &agr;1,3-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, and siayl Lewis X, which are structurally similar to certain tumor-associated carbohydrate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors. In addition the polypeptide of the invention can be used to develop diagnostic and research assays to determine the presence of H. pylori in human specimens.
    Type: Application
    Filed: July 3, 2002
    Publication date: September 4, 2003
    Applicant: The Governors of the University of Alberta, a Canadian corporation
    Inventors: Diane E. Taylor, Zhongming Ge
  • Alpha1,3-fucosyltransferase
    Publication number: 20030166212
    Abstract: A bacterial &agr;1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing &agr;1,3-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, and siayl Lewis X, which are structurally similar to certain tumor-associated carbohydrate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors. In addition the polypeptide of the invention can be used to develop diagnostic and research assays to determine the presence of H. pylori in human specimens.
    Type: Application
    Filed: March 17, 2003
    Publication date: September 4, 2003
    Applicant: Governors of the University of Alberta, a Canadian corporation
    Inventors: Diane E. Taylor, Zhongming Ge
  • Nucleic acids encoding &agr;-1,3 fucosyltransferases and expression systems for making and expressing them
    Patent number: 6534298
    Abstract: A bacterial &agr;1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing &agr;1,3-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, and siayl Lewis X, which are structurally similar to certain tumor-associated carbohydrate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors. In addition the polypeptide of the invention can be used to develop diagnostic and research assays to determine the presence of H. pylori in human specimens.
    Type: Grant
    Filed: December 7, 2000
    Date of Patent: March 18, 2003
    Assignee: The Govenors of the University of Alberta
    Inventors: Diane E. Taylor, Zhongming Ge
  • Alpha1,3-fucosyltransferase
    Publication number: 20020164749
    Abstract: A bacterial &agr;1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing &agr;1,3-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, and siayl Lewis X, which are structurally similar to certain tumor-associated carbohy-drate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors. In addition the polypeptide of the invention can be used to develop diagnostic and research assays to determine the presence of H. pylon in human specimens.
    Type: Application
    Filed: April 9, 2002
    Publication date: November 7, 2002
    Applicant: The Governors of the University of Alberta, a Canada corporation
    Inventors: Diane E. Taylor, Zhongming Ge
  • Nucleic acids encoding alpha-1,3 fucosyltransferases and expression systems for making and expressing them
    Publication number: 20020068347
    Abstract: A bacterial &agr;1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing &agr;1,3-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, and siayl Lewis X, which are structurally similar to certain tumor-associated carbohydrate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors. In addition the polypeptide of the invention can be used to develop diagnostic and research assays to determine the presence of H. pylori in human specimens.
    Type: Application
    Filed: December 7, 2000
    Publication date: June 6, 2002
    Applicant: The Governers of the University of Alberta, a Canada corporation
    Inventors: Diane E. Taylor, Zhongming Ge
  • &agr;1,3-fucosyltransferase
    Patent number: 6399337
    Abstract: A bacterial &agr;1,3-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing &agr;1,3-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, and siayl Lewis X, which are structurally similar to certain tumor-associated carbohydrate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors. In addition the polypeptide of the invention can be used to develop diagnostic and research assays to determine the presence of H. pylori in human specimens.
    Type: Grant
    Filed: June 5, 1998
    Date of Patent: June 4, 2002
    Assignee: The Governors of the University of Alberta
    Inventors: Diane E. Taylor, Zhongming Ge