Patents by Inventor Diane Heck

Diane Heck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Unique Dual-Action Therapeutics
    Publication number: 20120010168
    Abstract: A new family of therapeutics which provides a controlled-release delivery platform for non-steroidal anti-inflammatory agents on an ester or an ester-carbonate backbone is disclosed herein. These agents are reversible inhibitors of acetylcholinesterase and are thus useful for clinical conditions benefiting from inflammation suppression and cholinergic intervention. These compounds are of the general formula wherein n=0, 1; X?C, Si, and N+ and NSAID=ibuprofen, naproxen, indomethacin and diclofenac. Other embodiments are also disclosed.
    Type: Application
    Filed: November 3, 2009
    Publication date: January 12, 2012
    Inventors: Jeffrey Laskin, Diane Heck, Mou-Tuan Huan, Karine Fabio, C. Jeffrey Lacey, Sherri Young, Pramod Mohanta, Christophe Guillon, Ned Heindel
  • Fluorescent fused-ring traizoles that inhibit cell proliferation and uses thereof
    Patent number: 7598238
    Abstract: Fused-ring triazole compounds which inhibit proliferation of cells and exhibit a unique and intense fluorescence are provided. Also provided are methods for synthesizing these compounds and methods for using these compounds to inhibit cell proliferation and infection and to label and fluorescently detect selected molecules.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: October 6, 2009
    Assignees: University of Medicine and Dentistry of New Jersey, Rutgers, the State University, Lehigh University
    Inventors: Jeffrey D. Laskin, Ned Heindel, Diane Heck, Anna Marie Vetrano, Christophe Guillon, Peter DeMatteo
  • Fluorescent tags for amino acid and nucleic acid analysis
    Patent number: 7150967
    Abstract: Methods and kits for labeling and detecting thiol containing species and nucleic acids using mercurimethyl-dihydropsoralen compounds and derivatives thereof which intercalate nucleic acids and are highly reactive with thiol containing species are provided. Fluorescent reactions products of the mercurimethyl-dihydropsoralen compounds or derivatives thereof attached to a thiol containing species and nucleic acids fluorescently labeled with these reaction products are also provided.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: December 19, 2006
    Assignees: University of Medicine & Dentistry of New Jersey, Rutgers, the State University, Lehigh University, Buckman Laboratories International, Inc.
    Inventors: Jeffrey D. Laskin, Christine Martey, Ned Heindel, Marilyn Whittemore, Diane Heck
  • Fluorescent fused-ring triazoles that inhibit cell proliferation and uses thereof
    Publication number: 20060270664
    Abstract: Fused-ring triazole compounds which inhibit proliferation of cells and exhibit a unique and intense fluorescence are provided. Also provided are methods for synthesizing these compounds and methods for using these compounds to inhibit cell proliferation and infection and to label and fluorescently detect selected molecules.
    Type: Application
    Filed: July 28, 2006
    Publication date: November 30, 2006
    Inventors: Jeffrey Laskin, Ned Heindel, Diane Heck, Anna Vetrano, Christophe Guillon, Peter DeMatteo
  • Fluorescent fused-ring triazoles that inhibit cell proliferation and uses thereof
    Patent number: 7105511
    Abstract: Fused-ring triazole compounds which inhibit proliferation of cells and exhibit a unique and intense fluorescence are provided. Also provided are methods for synthesizing these compounds and methods for using these compounds to inhibit cell proliferation and infection and to label and fluorescently detect selected molecules.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: September 12, 2006
    Assignees: University of Medicine and Dentistry of New Jersey, Rutgers, the State University, Lehigh University
    Inventors: Jeffrey D. Laskin, Ned Heindel, Diane Heck, Anna Marie Vetrano, Christophe Guillon, Peter DeMatteo
  • Mammalian catalase-dependent oxidation processes and methods for stimulating oxidative activities
    Patent number: 7015022
    Abstract: A catalase-dependent enzymatic oxidation process wherein a substrate to be oxidized is contacted with catalase in the absence of hydrogen peroxide is provided. Also provided are methods for using this process in a variety of biomedical, clinical and diagnostic applications as well as industrial processes. A method for stimulating the enzymatic oxidation process by treatment with ultraviolet light and uses for this method are also provided.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: March 21, 2006
    Assignee: University of Medicine & Dentistry of New Jersey
    Inventors: Jeffrey D. Laskin, Anna Marie Vetrano, Diane Heck
  • Fluorescent fused-ring triazoles that inhibit cell proliferation and uses thereof
    Publication number: 20060040926
    Abstract: Fused-ring triazole compounds which inhibit proliferation of cells and exhibit a unique and intense fluorescence are provided. Also provided are methods for synthesizing these compounds and methods for using these compounds to inhibit cell proliferation and infection and to label and fluorescently detect selected molecules.
    Type: Application
    Filed: August 19, 2004
    Publication date: February 23, 2006
    Inventors: Jeffrey Laskin, Ned Heindel, Diane Heck, Anna Vetrano, Christophe Guillon, Peter DeMatteo
  • Fluorescent tags for amino acid and nucleic acid analysis
    Publication number: 20040018517
    Abstract: Methods and kits for labeling and detecting thiol containing species and nucleic acids using mercurimethyl-dihydropsoralen compounds and derivatives thereof which intercalate nucleic acids and are highly reactive with thiol containing species are provided. Fluorescent reactions products of the mercurimethyl-dihydropsoralen compounds or derivatives thereof attached to a thiol containing species and nucleic acids fluorescently labeled with these reaction products are also provided.
    Type: Application
    Filed: April 4, 2003
    Publication date: January 29, 2004
    Inventors: Jeffrey D. Laskin, Christine Martey, Ned Heindel, Marilyn Whittemore, Diane Heck
  • Mammalian catalase-dependent oxidation processes and methods for stimulating oxidative activities
    Publication number: 20030228648
    Abstract: A catalase-dependent enzymatic oxidation process wherein a substrate to be oxidized is contacted with catalase in the absence of hydrogen peroxide is provided. Also provided are methods for using this process in a variety of biomedical, clinical and diagnostic applications as well as industrial processes. A method for stimulating the enzymatic oxidation process by treatment with ultraviolet light and uses for this method are also provided.
    Type: Application
    Filed: June 7, 2002
    Publication date: December 11, 2003
    Inventors: Jeffrey D. Laskin, Anna Marie Vetrano, Diane Heck