Patents by Inventor Diane L. Kozwich

Diane L. Kozwich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200009095
    Abstract: Set forth herein is a preparation of ibuprofen (2-(4-isobutylphenyl) propionic acid) in the free acid form that is suitable for topical administration. The topical ibuprofen formulation is prepared by dissolving the free acid form of ibuprofen, or preparing a homogeneous suspension of the free acid form of ibuprofen, in the presence of a pharmaceutically acceptable solvent so as to produce a topical drug formulation compatible with the penetration of 2-(4-isobutylphenyl) propionic acid through the skin tissue. Topical formulations of ibuprofen can be based on a pharmaceutically acceptable solvent such as, e.g., a pyrrolidone solvent or dimethylacetamide.
    Type: Application
    Filed: September 19, 2019
    Publication date: January 9, 2020
    Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich
  • Patent number: 10322077
    Abstract: Methods and formulations for removing a tattoo by using a cell disrupter in combination with a vasodilator, and optionally one or more of an osmotic modifying agent, a chelation agent, and an occlusive modifying agent. Embodiments optionally further include using one or more of an antibiotic, anesthetic, penetration enhancer, excipient, carrier and vehicle.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: June 18, 2019
    Assignee: BioChemics, Inc.
    Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich, Laura Stephens, John J. Masiz, David H. Donabedian
  • Publication number: 20160213586
    Abstract: Methods and formulations for removing a tattoo by using a cell disrupter in combination with a vasodilator, and optionally one or more of an osmotic modifying agent, a chelation agent, and an occlusive modifying agent. Embodiments optionally further include using one or more of an antibiotic, anesthetic, penetration enhancer, excipient, carrier and vehicle.
    Type: Application
    Filed: January 28, 2016
    Publication date: July 28, 2016
    Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich, Laura Stephens, John J. Masiz, David H. Donabedian
  • Patent number: 9278233
    Abstract: Methods and formulations for removing a tattoo by using a cell disrupter in combination with a vasodilator, and optionally one or more of an osmotic modifying agent, a chelation agent, and an occlusive modifying agent. Embodiments optionally further include using one or more of an antibiotic, anesthetic, penetration enhancer, excipient, carrier and vehicle.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: March 8, 2016
    Assignee: BioChemics, Inc.
    Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich, Laura Stephens, John J. Masiz, David H. Donabedian
  • Patent number: 8802085
    Abstract: A method for treating a patient suffering from a wound, ulcer, or inflammation includes providing a topical formulation comprising a carrier and a combination of active ingredients that includes at least one retinoid and at least one blood vessel dilator, and applying the topical formulation to the skin of the patient to cause healing, accelerated healing or prevention of the wound, ulcer or inflammation. Additional active ingredients may include a promoter of mitochondrial function or an antioxidant.
    Type: Grant
    Filed: December 4, 2012
    Date of Patent: August 12, 2014
    Assignee: BioChemics, Inc.
    Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich
  • Patent number: 8343486
    Abstract: A method for treating a patient suffering from a wound, ulcer, or inflammation includes providing a topical formulation comprising a carrier and a combination of active ingredients that includes at least one retinoid and at least one blood vessel dilator, and applying the topical formulation to the skin of the patient to cause healing, accelerated healing or prevention of the wound, ulcer or inflammation. Additional active ingredients may include a promoter of mitochondrial function or an antioxidant.
    Type: Grant
    Filed: January 22, 2009
    Date of Patent: January 1, 2013
    Assignee: BioChemics, Inc.
    Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich
  • Publication number: 20120329875
    Abstract: Set forth herein is a preparation of ibuprofen (2-(4-isobutylphenyl) propionic acid) in the free acid form that is suitable for topical administration. The topical ibuprofen formulation is prepared by dissolving the free acid form of ibuprofen, or preparing a homogeneous suspension of the free acid form of ibuprofen, in the presence of a pharmaceutically acceptable solvent so as to produce a topical drug formulation compatible with the penetration of 2-(4-isobutylphenyl) propionic acid through the skin tissue. Topical formulations of ibuprofen can be based on a pharmaceutically acceptable solvent such as, e.g., a pyrrolidone solvent or dimethylacetamide.
    Type: Application
    Filed: September 5, 2012
    Publication date: December 27, 2012
    Applicant: BioChemics, Inc.
    Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich
  • Publication number: 20100145256
    Abstract: Methods and formulations for removing a tattoo by using a cell disrupter in combination with a vasodilator, and optionally one or more of an osmotic modifying agent, a chelation agent, and an occlusive modifying agent. Embodiments optionally further include using one or more of an antibiotic, anesthetic, penetration enhancer, excipient, carrier and vehicle.
    Type: Application
    Filed: December 4, 2009
    Publication date: June 10, 2010
    Applicant: BioChemics, Inc.
    Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich, Laura Stephens, John J. Masiz, David H. Donabedian
  • Publication number: 20100137443
    Abstract: Set forth herein is a preparation of ibuprofen (2-(4-isobutylphenyl)propionic acid) in the free acid form that is suitable for topical administration. The topical ibuprofen formulation is prepared by dissolving the free acid form of ibuprofen, or preparing a homogeneous suspension of the free acid form of ibuprofen, in the presence of a pharmaceutically acceptable solvent so as to produce a topical drug formulation compatible with the penetration of 2-(4-isobutylphenyl) propionic acid through the skin tissue. Topical formulations of ibuprofen can be based on a pharmaceutically acceptable solvent such as, e.g., a pyrrolidone solvent or dimethylacetamide.
    Type: Application
    Filed: September 10, 2009
    Publication date: June 3, 2010
    Applicant: BIOCHEMICS, INC.
    Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich
  • Publication number: 20090214504
    Abstract: A method for treating a patient suffering from a wound, ulcer, or inflammation includes providing a topical formulation comprising a carrier and a combination of active ingredients that includes at least one retinoid and at least one blood vessel dilator, and applying the topical formulation to the skin of the patient to cause healing, accelerated healing or prevention of the wound, ulcer or inflammation. Additional active ingredients may include a promoter of mitochondrial function or an antioxidant.
    Type: Application
    Filed: January 22, 2009
    Publication date: August 27, 2009
    Applicant: BIOCHEMICS, INC.
    Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich
  • Patent number: 6649378
    Abstract: Self-contained devices are described that integrate nucleic acid extraction, specific target amplification and detection into a single device. This integration permits rapid and accurate nucleic acid sequence detection. The invention may be used, for example, in the screening for nucleic acid sequences which may be indicative of genetic defects or contagious diseases, as well as for monitoring efficacy in the treatment of contagious diseases.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: November 18, 2003
    Assignee: Xtrana, Inc.
    Inventors: Diane L. Kozwich, John C. Gerdes
  • Patent number: 6153425
    Abstract: A self-contained device is described that integrates nucleic acid extraction, specific target amplification and detection into a single device. This integration permits rapid and accurate nucleic acid sequence detection. The invention may be used, for example, in the screening for nucleic acid sequences which may be indicative of genetic defects or contagious diseases, as well as for monitoring efficacy in the treatment of contagious diseases.
    Type: Grant
    Filed: August 27, 1998
    Date of Patent: November 28, 2000
    Assignee: Xtrana, Inc.
    Inventors: Diane L. Kozwich, John C. Gerdes
  • Patent number: 5955351
    Abstract: A self-contained device is described that integrates nucleic acid extraction, specific target amplification and detection into a single device. This integration permits rapid and accurate nucleic acid sequence detection. The invention may be used, for example, in the screening for nucleic acid sequences which may be indicative of genetic defects or contagious diseases, as well as for monitoring efficacy in the treatment of contagious diseases.
    Type: Grant
    Filed: July 12, 1996
    Date of Patent: September 21, 1999
    Inventors: John C. Gerdes, Lynn D. Jankovsky, Diane L. Kozwich