Patents by Inventor Diane McCarthy

Diane McCarthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150204881
    Abstract: The present invention relates to the use of N-linked glycan profiles of blood or blood component proteins as biomarkers for diagnosing diabetes mellitus and for monitoring the efficacy of anti-diabetic therapy. Specifically, the present invention relates to detecting changes in the amounts of N-linked glycans as diagnostic biomarkers for diabetes mellitus and as indicators of the efficacy of anti-diabetic therapy over time.
    Type: Application
    Filed: April 19, 2013
    Publication date: July 23, 2015
    Inventors: Hidehisa Asada, Diane Mccarthy, Yoshiaki Miura, Taku Nakahara
  • Publication number: 20150083906
    Abstract: The use of N-linked glycosylation pattern of serum proteins as a biomarker for evaluating the efficacy of intervention therapies for diabetes is disclosed. As disclosed herein, changes in the N-linked glycosylation of total plasma proteins precedes and predicts the decrease in glycated hemoglobin (HbA1c) associated with successful treatment of diabetes. Therefore, measuring changes in N-linked glycosylation of total serum plasma proteins over time may be used as a biomarker to evaluate or access the efficacy of an intervention therapy for diabetes.
    Type: Application
    Filed: April 16, 2013
    Publication date: March 26, 2015
    Inventors: Huseyin Mehmet, Sandra C. Souza, Hidehisa Asada, Yoshiaki Miura, Taku Nakahara, Diane McCarthy
  • Publication number: 20150072888
    Abstract: The present invention relates to the use of N-linked glycan profiles of blood or blood component proteins as biomarkers for diagnosing diabetes mellitus and for monitoring the efficacy of anti-diabetic therapy. Specifically, the present invention relates to detecting changes in the amounts of N-linked glycans as diagnostic biomarkers for diabetes mellitus and as indicators of the efficacy of anti-diabetic therapy over time.
    Type: Application
    Filed: April 19, 2013
    Publication date: March 12, 2015
    Inventors: Hidehisa Asada, Diane McCarthy, Yoshiaki Miura, Taku Nakahara