Patents by Inventor Didier Bazile

Didier Bazile has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Functional PLA-PEG copolymers, the nanoparticles thereof, their preparation and use for targeted drug delivery and imaging
    Patent number: 9364444
    Abstract: Functional PLA-PEG copolymers, the nanoparticles thereof, their preparation and use for targeted drug delivery and imaging The present invention concerns novel functional PEG-PLA containing copolymers, the nanoparticles containing the same, their process of preparation and their use for site specific targeted drug delivery and imaging.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: June 14, 2016
    Inventors: Didier Bazile, Patrick Couvreur, Harivardhan Reddy Lakkireddy, Nicolas Mackiewicz, Julien Nicolas
  • Polymeric conjugates of active principles, their process of preparation and their polymeric intermediates
    Patent number: 9278137
    Abstract: The present invention relates to novel conjugates of active principles grafted to a polymer, to the nanoparticles comprising them, to their preparation and to their polymeric intermediates.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: March 8, 2016
    Assignees: SANOFI, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE PAUL SABATIER TOULOUSE III
    Inventors: Abderrhamane Amgoune, Didier Bazile, Fethi Bensaid, Didier Bourissou, Eric Didier, Stephanie Greco, Harivardhan Reddy Lakkireddy, Serge Sable, Michel Veillard
  • Functional PLA-PEG Copolymers, the Nanoparticles Thereof, Their Preparation and Use for Targeted Drug Delivery and Imaging
    Publication number: 20150037419
    Abstract: Functional PLA-PEG copolymers, the nanoparticles thereof, their preparation and use for targeted drug delivery and imaging The present invention concerns novel functional PEG-PLA containing copolymers, the nanoparticles containing the same, their process of preparation and their use for site specific targeted drug delivery and imaging.
    Type: Application
    Filed: February 28, 2013
    Publication date: February 5, 2015
    Inventors: Didier Bazile, Patrick Couvreur, Harlvardhan Reddy Lakkireddy, Nicolas Mackiewicz, Julien Nicolas
  • POLYMERIC CONJUGATES OF ACTIVE PRINCIPLES, THEIR PROCESS OF PREPARATION AND THEIR POLYMERIC INTERMEDIATES
    Publication number: 20130243719
    Abstract: The present invention relates to novel conjugates of active principles grafted to a polymer, to the nanoparticles comprising them, to their preparation and to their polymeric intermediates.
    Type: Application
    Filed: November 18, 2011
    Publication date: September 19, 2013
    Applicants: SANOFI, UNIVERSITE PAUL SABATIER TOULOUSE III, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Abderrhamane Amgoune, Didier Bazile, Fethi Bensaid, Didier Bourissou, Eric Didier, Stephanie Greco, Harivardhan Reddy Lakkireddy, Serge Sable, Michel Veillard
  • Method for Preparing Calibrated Biodegradable Microspheres
    Publication number: 20080233201
    Abstract: The invention relates to a method for preparing monodispersed biodegradable microspheres consisting in a) preparing an emulsion containing at least one polymeric phase and at least one aqueous phase at a viscosity ratio between the dispersed polymeric phase and the aqueous phase ranging from 0.12 to 10, b) exposing the thus obtained emulsion to a controlled laminar shear strength, c) removing a solvent from the polymeric phase and in d) isolating the thus obtained microspheres. The use of the prepared microspheres is also disclosed.
    Type: Application
    Filed: March 3, 2005
    Publication date: September 25, 2008
    Inventors: Audrey Royere, Didier Bazile, Jerome Bibette
  • Monodispersed solid lipid particle compositions
    Publication number: 20070053988
    Abstract: A composition includes a monodispersed lipid phase which is dispersed in a continuous aqueous phase, wherein the lipid phase includes at least one crystallizable lipid, at least one active ingredient and at least one compound including two chains of fatty acids and one glycol polyethylene chain. A method for the preparation of the compositions via a simple monodispersed O/W or O/W/O double emulsion is also disclosed.
    Type: Application
    Filed: September 30, 2004
    Publication date: March 8, 2007
    Inventors: Audrey Royere, Jerome Bibette, Didier Bazile
  • Nucleic acid-containing composition, its preparation and use
    Patent number: 5856435
    Abstract: The present invention relates to compositions comprising nucleic acids and oligopeptides, and their use in therapy and in gene therapy, in particular for the transfer of nucleic acids.
    Type: Grant
    Filed: August 26, 1996
    Date of Patent: January 5, 1999
    Assignee: Rhone-Poulenc Rorer SA
    Inventors: Didier Bazile, Carole Emile, Claude Helene, Gilles Spenlehauer
  • Process for preparing nanoparticles
    Patent number: 5766635
    Abstract: Nanoparticles are prepared by dissolving a poly(ethylene oxide) and/or poly(propylene oxide) polylactic copolymer in an organic solvent followed by formation of nanoparticles by mixing the solution containing the polymer with an aqueous solution and by precipitation, without using an additional colloidal protective agent or by microfluidization and solvent evaporation. Nanoparticles prepared by this method are disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 16, 1998
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Gilles Spenleuhauer, Didier Bazile, Michel Veillard, Christian Prud'Homme, Jean-Paul Michalon
  • Nanoparticles based on a polyoxyethelene and polyactic acid block copolymer
    Patent number: 5683723
    Abstract: The invention discloses nanoparticles offering an extended time before capture by the reticulo-endothelial system. Said particles are composed of an ethylene and/or propylene polyoxide polylactic copolymer optionally mixed with a polylactic polymer.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 4, 1997
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Gilles Spenlehauer, Didier Bazile, Michel Veillard, Christian Prud'Homme, Jean-Paul Michalon