Patents by Inventor Dieter Sauerbier

Dieter Sauerbier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid oral dosage forms of ifosfamide
    Patent number: 5158776
    Abstract: Solid oral ifosfamide formulations comprising a capsule containing a mass which consists essentially of the active substance ifosfamide and microcrystalline cellulose, or in the form of tablets which contain, in relation to one part by weight of ifosfamide,0.1-1.0 parts by weight of tribasic calcium phosphate and0.04-0.4 parts by weight of polyethylene glycol as well as in addition, related to the weight of the tablet5-60% by weight of a filling and flow regulating agent1-10% by weight of a disintegrant0.1-10% by weight of an antiadhesion agent and0.1-80% by weight of a binding agent.
    Type: Grant
    Filed: July 24, 1991
    Date of Patent: October 27, 1992
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Dieter Sauerbier, Jurgen Engel, Eckhard Milsmann, Klaus Molge, Otto Isaac
  • Ifosfamide-mesna lyophilizate and process for its preparation
    Patent number: 4959215
    Abstract: An ifosfamide-mesna lyophilizate consists substantially of ifosfamide, 0.1-1.0 parts by weight of mesna and 0.1 to 17 parts by weight of hexitol. The product is obtained by freeze drying an aqueous or aqueous-ethanolic solution of ifosfamide and mesna.
    Type: Grant
    Filed: March 20, 1989
    Date of Patent: September 25, 1990
    Assignee: Asta Pharma AG
    Inventors: Dieter Sauerbier, Otto Isaac, Wolfgang P. Brade
  • Solutions of oxaphosphorins having improved stability and process for the preparation thereof
    Patent number: 4952575
    Abstract: Solutions comprising oxazaphosphorins having the general formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are radicals and at least two of said radicals are 2-chloroethyl and/or 2-mathanesulfonyloxyethyl and the remaining radical is selected from hydrogen, methyl and ethyl; and about 80% to about 100% (v/v) ethanol; wherein the oxazaphosphorin concentration is about 10% to about 70% (w/v); and a process for the preparation thereof.
    Type: Grant
    Filed: February 6, 1989
    Date of Patent: August 28, 1990
    Assignee: Asta Pharma Aktiengesellschaft
    Inventors: Dieter Sauerbier, Klaus Molge, Werner Weigert, Otto Issac