Patents by Inventor Dietmar Appelhans

Dietmar Appelhans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10022395
    Abstract: The subject matter of the invention relates to the method of administering the polypropyleneimine dendrimer of the fourth generation, coated with maltotriose, of a general formula I, wherein 25 to 45% of R substituents stand for a maltotriose residue and each of the remaining R substituents is H, to a human subject. The dendrimer of the formula I is designated in short as PPI-G4-OS-Mal-III, where PPI-G4 stands for the 4th generation of polypropyleneimine dendrimer, OS (Open Shell)—for open coat, Mal-III for maltotriose (trisaccharide made of 3 ?-glucose residues).
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: July 17, 2018
    Assignee: UNIWERSYTET LODZKI
    Inventors: Ida Franiak-Pietryga, Maria Bryszewska, Dietmar Appelhans, Barbara Klajnert-Maculewicz
  • Publication number: 20180153927
    Abstract: The subject matter of the invention relates to the method of administering the polypropyleneimine dendrimer of the fourth generation, coated with maltotriose, of a general formula I, wherein 25 to 45% of R substituents stand for a maltotriose residue and each of the remaining R substituents is H, to a human subject. The dendrimer of the formula I is designated in short as PPI-G4-OS-Mal-III, where PPI-G4 stands for the 4th generation of polypropyleneimine dendrimer, OS (Open Shell)—for open coat, Mal-III for maltotriose (trisaccharide made of 3 ?-glucose residues).
    Type: Application
    Filed: December 18, 2017
    Publication date: June 7, 2018
    Applicant: UNIWERSYTET LODZKI
    Inventors: IDA FRANIAK-PIETRYGA, Maria Bryszewska, Dietmar Appelhans, Barbara Klajnert-Maculewicz
  • Patent number: 9877985
    Abstract: The application of maltotriose-coated 4th generation polypropyleneimine dendrimer PPI-G4-OS-Mal-III containing 25-45% of peripheral amines groups coated with maltotriose particles to make a drug for treating neoplastic proliferation diseases, particularly chronic lymphocytic leukemia.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: January 30, 2018
    Assignee: UNIWERSYTET LODZKI
    Inventors: Ida Franiak-Pietryga, Maria Bryszewska, Dietmar Appelhans, Barbara Klajnert-Maculewicz
  • Publication number: 20150320692
    Abstract: The application of maltotriose-coated 4th generation polypropyleneimine dendrimer PPI-G4-DS-Mal-III containing 80-95% of peripherial amines groups coated with maltotriose particles to make a drug for treating neoplastic proliferation diseases, particularly chronic lymphocytic leukemia.
    Type: Application
    Filed: December 3, 2013
    Publication date: November 12, 2015
    Inventors: IDA FRANIAK-PIETRYGA, MARIA BRYSZEWSKA, DIETMAR APPELHANS, BARBARA KLAJNERT-MACULEWICZ
  • Patent number: 8728504
    Abstract: A process for solubilizing hydrophobic active ingredients in aqueous medium, which comprises using, as an assistant, at least one hyperbranched polymer (A) which is obtainable by reacting at least one hyperbranched polymeric compound having at least one primary or secondary amino group per molecule (a), selected from (a1) hyperbranched polyamides and (a2) hyperbranched polyureas, with (b) at least one mono-, di- or oligosaccharide.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: May 20, 2014
    Assignee: BASF SE
    Inventors: Bernd Bruchmann, Holger Türk, Daniel Schönfelder, Monika Haberecht, Dietmar Appelhans, Victor Boyko
  • Publication number: 20110195844
    Abstract: A process for solubilizing hydrophobic active ingredients in aqueous medium, which comprises using, as an assistant, at least one hyperbranched polymer (A) which is obtainable by reacting at least one hyperbranched polymeric compound having at least one primary or secondary amino group per molecule (a), selected from (a1) hyperbranched polyamides and (a2) hyperbranched polyureas, with (b) at least one mono-, di- or oligosaccharide.
    Type: Application
    Filed: February 4, 2011
    Publication date: August 11, 2011
    Applicant: BASF SE
    Inventors: Bernd Bruchmann, Holger Türk, Daniel Schönfelder, Monika Haberecht, Dietmar Appelhans, Victor Boyko
  • Publication number: 20110177602
    Abstract: A composite structure, for marking biomolecules in a biological, biochemical or medicinal system, comprises: at least one nano particle and at least one dendritic macromolecule, which has an inner region with branched, especially perfectly branched to highly branched, structures and a periphery, which comprises surface groups of the dendritic macromolecule, wherein a plurality, especially more than 50%, of the surface groups have in the periphery of the dendritic macromolecule, in each case, at least one functional group of first type, wherein the functional group of first type comprises at least one monosaccharide-, oligosaccharide- and/or polysaccharide unit, and wherein the dendritic macromolecule stabilizes the nano particle.
    Type: Application
    Filed: June 24, 2009
    Publication date: July 21, 2011
    Applicant: Endress + Hauser Conducts Gesellschaft furMess-und Regeltechnik mbH +Co. KG
    Inventors: Dietmar Appelhans, Mathias Lakatos, Wolfgang Pompe
  • Patent number: 7141276
    Abstract: The invention is used in the field of chemistry and relates to coatings which can be used, for example, for the production of paint films, and a method for production thereof. The object of the invention is to describe permanent coatings with hydrophobic to ultrahydrophobic properties. The object is attained by hydrophobic permanent coatings of a crosslinked layer of a hardener component (A) and resin component (B), whereby (A) and/or (B) comprise chemically coupled lateral and/or terminal perfluoroalkyl groups with at least one trifluoromethyl end group, with a coupling between the layer and the surface region of the substrate.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: November 28, 2006
    Assignee: Leibniz-Institut Fuer Polymerforschung Dresden E.V.
    Inventors: Dieter Lehmann, Dietmar Appelhans, Michaela Gedan-Smolka