Abstract: Disclosed are a method and a device for determining characteristics of particles dispersed in gases and liquids in the nano- and microscale size ranges and the number distribution and concentration thereof by use of particle photometry. This can be achieved by producing scattered light measurements in a photometer for a different number of aperture or receiving angles and evaluating particle characteristics from the determined scattered light intensities using evaluation algorithms. The determination of particle characteristics over a size range of several decades is made possible without the need to change or adapt the geometry of the sample measurement chamber.

Abstract: A centrifuge rotor for measuring a characteristic of a sample subjected to centrifugation, the centrifuge rotor including: a rotor body; at least one sample holder for holding a sample; at least one on-board measurement device for measuring a characteristic of the sample held in the at least one sample holder during rotation of the rotor.

Abstract: A method and a device for the automatic determination of selected physical and colloidal chemistry parameters by determining the attenuation of radiated waves through monodisperse or polydisperse dispersion samples subjected to gravitation or centrifugation, wherein during the segregation by means of centrifugation or gravitation, the instantaneous transmission IT(t, r) characterizing the current segregation status of the waves radiated with the intensity Io(t, r) and/or the instantaneous scattering IS(t, r) as a function of the position within the samples is repeatedly determined and recorded at high resolution at any arbitrary time for one or more wavelengths over the entire length of the sample or in selected partial sections of it, simultaneously for multiple and even concentrated samples with known and/or unknown physical and colloidal chemistry properties.

Abstract: A centrifuge rotor for measuring a characteristic of a sample subjected to centrifugation, the centrifuge rotor including: a rotor body; at least one sample holder for holding a sample; at least one on-board measurement device for measuring a characteristic of the sample held in the at least one sample holder during rotation of the rotor.

Abstract: Modeling the gravitational field-induced or centrifugal field-induced separation of particles of a dispersion by use of one or more additional force fields that also influence the migration of the particles. A method includes detecting and measuring the modified separation behavior with the help of concentration-measuring sensors. The force acting upon the particles can be calculated from the change in velocity of the particles, and the corresponding particle properties can be calculated if the respective field intensities are known.

Abstract: A method and a device for the automatic determination of selected physical and colloidal chemistry parameters by determining the attenuation of radiated waves through monodisperse or polydisperse dispersion samples subjected to gravitation or centrifugation, wherein during the segregation by means of centrifugation or gravitation, the instantaneous transmission IT(t, r) characterizing the current segregation status of the waves radiated with the intensity Io(t, r) and/or the instantaneous scattering IS(t, r) as a function of the position within the samples is repeatedly determined and recorded at high resolution at any arbitrary time for one or more wavelengths over the entire length of the sample or in selected partial sections of it, simultaneously for multiple and even concentrated samples with known and/or unknown physical and colloidal chemistry properties.

Abstract: A method and a device for the automatic determination of selected physical and colloidal chemistry parameters by determining the attenuation of radiated waves through monodisperse or polydisperse dispersion samples subjected to gravitation or centrifugation, wherein during the segregation by means of centrifugation or gravitation, the instantaneous transmission IT(t, r) characterizing the current segregation status of the waves radiated with the intensity Io(t, r) and/or the instantaneous scattering IS(t, r) as a function of the position within the samples is repeatedly determined and recorded at high resolution at any arbitrary time for one or more wavelengths over the entire length of the sample or in selected partial sections of it, simultaneously for multiple and even concentrated samples with known and/or unknown physical and colloidal chemistry properties.

Abstract: The aim of the invention is to model the gravitational field-induced or centrifugal field-induced separation of particles of a dispersion by means of one or more additional force fields that also influence the migration of the particles. Said aim is achieved by detecting and measuring the modified separation behavior with the help of concentration-measuring sensors. The force acting upon the particles can be calculated from the change in velocity of the particles, and the corresponding particle properties can be calculated if the respective field intensities are known.

Abstract: A method is disclosed for the preparation of isomorphic and nonspherical shape standards as isometric as possible and their mixtures for validation of the measurement methods and analyzers for quantification of particle shapes and their characteristics especially in the microscale and nanoscale size range. Furthermore the shape standards also provide quality control and performance qualification can be used at the operator of the corresponding shape measurement devices.

Abstract: The invention relates to a method for preserving samples and disrupting cells which can be employed for the preparation of the extraction of nucleic acids from live cells, cell aggregates and tissue samples, and to a kit for carrying out the method. The method includes the introduction of live cells, cell aggregates or tissue samples whose nucleic acids are to be extracted into an excess of water-miscible and volatile organic liquid. The saturation of the sample with the organic liquid has an advantageous effect on the extraction of the nucleic acids, which is subsequently carried out in an aqueous medium. The mechanical cell disruption is facilitated by the virtually complete removal of the water from the cells. The biomembranes are dissolved in the organic liquid. tRNA and other RNA fractions with a low degree of polymerization, which are capable of permeating across the cell wall, can be extracted selectively without mechanical disruption.

Abstract: The aim of the invention is to model the gravitational field-induced or centrifugal field-induced separation of particles of a dispersion by means of one or more additional force fields that also influence the migration of the particles. Said aim is achieved by detecting and measuring the modified separation behavior with the help of concentration-measuring sensors. The force acting upon the particles can be calculated from the change in velocity of the particles, and the corresponding particle properties can be calculated if the respective field intensities are known.

Abstract: This invention relates to an automatic sample collector for liquids which are discharged from a chromatographic column, a dialysis apparatus, or a reaction container, for example, and are consecutively collected at a give volume division, a method for collecting samples of a liquid in a predefined chronological sequence, and uses of the inventive sample collector. The volume is divided by assigning one or several gas-permeable liquid barriers (4, 5) to each collection container (3). The sample collector can be produced as one piece which is for single use and is made of polypropylene, Teflon, or other suitable materials. The inventive sample collector has the advantage that it requires no source of energy and can be autoclaved and miniaturized, among other things. The design of the inventive sample collector makes it possible to keep the content of the collection containers free from oxygen or immediately freeze the liquid flowing into the collection containers.

Abstract: The invention relates to a method and a device for the automatic determination of selected physical and colloidal chemistry parameters (for example, the grain size, the distribution of grain sizes, the hindrance function and indices of structural stability) by means of the determination of the attenuation of radiated waves through monodisperse or polydisperse dispersion samples subjected to gravitation or centrifugation, characterised in that during the segregation by means of centrifugation or gravitation, the instantaneous transmission IT(t, r) characterising the current segregation status of the waves radiated with the intensity Io(t, r) and/or the instantaneous scattering IS(t, r) as a function of the position within the samples is repeatedly determined and recorded at high resolution at any arbitrary time for one or more wavelengths over the entire length of the sample or in selected partial sections of it, simultaneously for multiple and even concentrated samples with known and/or unknown physical and c

Abstract: This invention relates to an automatic sample collector for liquids which are discharged from a chromatographic column, a dialysis apparatus, or a reaction container, for example, and are consecutively collected at a give volume division, a method for collecting samples of a liquid in a predefined chronological sequence, and uses of the inventive sample collector. The volume is divided by assigning one or several gas-permeable liquid barriers (4, 5) to each collection container (3). The sample collector can be produced as one piece which is for single use and is made of polypropylene, Teflon, or other suitable materials. The inventive sample collector has the advantage that it requires no source of energy and can be autoclaved and miniaturized, among other things. The design of the inventive sample collector makes it possible to keep the content of the collection containers free from oxygen or immediately freeze the liquid flowing into the collection containers.

Abstract: The invention relates to methods and devices for accelerated stability analysis, and in particular to a qualitative and quantitative direct estimation/identification of separation processes of disperse material systems (such as liquid-solid, liquid-liquid or liquid-gaseous). The invention also relates to methods and devices for the classification and quantitative characterization of slow, as well as rapid separation phenomena of disperse material systems of different volume concentration. Exemplary fields of application concern the development, selection and optimization of destabilizers, stabilizers and novel formulations for dispersions, as well as quality and process control (such as in the chemical, pharmaceutical, biotechnological, cosmetic and food industries), as well as in the process technology for separation and treatment processes.

Abstract: The invention relates to methods and devices for accelerated stability analysis, and in particular to a qualitative and quantitative direct estimation/identification of separation processes of disperse material systems (such as liquid-solid, liquid-liquid or liquid-gaseous). The invention also relates to methods and devices for the classification and quantitative characterization of slow, as well as rapid separation phenomena of disperse material systems of different volume concentration. Exemplary fields of application concern the development, selection and optimization of destabilizers, stabilizers and novel formulations for dispersions, as well as quality and process control (such as in the chemical, pharmaceutical, biotechnological, cosmetic and food industries), as well as in the process technology for separation and treatment processes.