Patents by Inventor Dietmar Nussbaumer

Dietmar Nussbaumer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8343350
    Abstract: The invention comprises a membrane and device and method for removing proteases from fluids, particularly from biological fluids and pharmaceutical solutions, which uses a microporous membrane body, whereby inhibitors that selectively bind proteases are coupled to the membrane body by chemically activated groups.
    Type: Grant
    Filed: June 17, 2003
    Date of Patent: January 1, 2013
    Assignee: Sartorius AG
    Inventors: Wolfgang Demmer, Dietmar Nussbaumer, Hans-Heinrich Hörl
  • Patent number: 8343351
    Abstract: The invention comprises a membrane and device and method for removing proteases from fluids, particularly from biological fluids and pharmaceutical solutions, which uses a microporous membrane body, whereby inhibitors that selectively bind proteases are coupled to the membrane body by chemically activated groups.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: January 1, 2013
    Assignee: Sartorius AG
    Inventors: Wolfgang Demmer, Dietmar Nussbaumer, Hans-Heinrich Hörl
  • Publication number: 20110147292
    Abstract: There is provided a cellulose hydrate membrane having a porous double structure which consists of micropores having a diameter in the range from >100 nm to 20 ?m and ultrapores which have a diameter of <100 nm and which are not accessible to Blue Dextran having an average molecular weight Mw of 2 000 000, wherein the fraction of the volume of the ultrapores is more than 15% of the entire pore volume accessible to water. In addition, a method for producing the membrane, its use as an adsorption membrane, and an apparatus for membrane chromatography are specified.
    Type: Application
    Filed: February 10, 2009
    Publication date: June 23, 2011
    Applicant: SARTORIUS STEDIM BIOTECH GMBH
    Inventors: Wolfgang Demmer, René Faber, Hans-Heinrich Hörl, Csilla Kiss, Dietmar Nußbaumer
  • Patent number: 7422686
    Abstract: There is disclosed a process for the production of cellulose hydrate ultrafiltration membranes having improved filtration performance and the ultrafiltration membranes produced by the process.
    Type: Grant
    Filed: November 1, 2005
    Date of Patent: September 9, 2008
    Assignee: Sartorius Stedim Biotech GmbH
    Inventors: Dietmar Nussbaumer, Hans-Heinrich Hörl
  • Publication number: 20080128358
    Abstract: The present invention relates to a process which can be carried out continuously for the adsorption separation of substances in liquid media, in which process a flat adsorbent is loaded with an adsorbate by contacting the adsorbate-containing medium with the entire adsorbing outer surface of the adsorbent without forced flow through, and to an apparatus for carrying out the inventive process.
    Type: Application
    Filed: October 25, 2007
    Publication date: June 5, 2008
    Applicant: Sartorius Stedim Biotech GmbH
    Inventors: Dietmar Nussbaumer, Wolfgang Demmer
  • Patent number: 7311832
    Abstract: The present invention relates to adsorption membranes comprising microporous polymer membranes in which adsorbent particles are incorporated. Furthermore, the present invention relates to a method of producing the inventive adsorption membranes as well as devices which comprise the inventive adsorption membranes.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: December 25, 2007
    Assignee: Sartorius Stedim Biotech GmbH
    Inventors: Wolfgang Demmer, Stefan Fischer-Fruehholz, Andreas Kocourek, Dietmar Nussbaumer, Eberhard Wuenn
  • Publication number: 20060216807
    Abstract: The invention comprises a membrane and device and method for removing proteases from fluids, particularly from biological fluids and pharmaceutical solutions, which uses a microporous membrane body, whereby inhibitors that selectively bind proteases are coupled to the membrane body by chemically activated groups.
    Type: Application
    Filed: May 17, 2006
    Publication date: September 28, 2006
    Inventors: Wolfgang Demmer, Dietmar Nussbaumer, Hans-Heinrich Horl
  • Publication number: 20060096912
    Abstract: There is disclosed a process for the production of cellulose hydrate ultrafiltration membranes having improved filtration performance and the ultrafiltration membranes produced by the process.
    Type: Application
    Filed: November 1, 2005
    Publication date: May 11, 2006
    Inventors: Dietmar Nussbaumer, Hans-Heinrich Horl
  • Publication number: 20050245431
    Abstract: The invention comprises a membrane and device and method for removing proteases from fluids, particularly from biological fluids and pharmaceutical solutions, which uses a microporous membrane body, whereby inhibitors that selectively bind proteases are coupled to the membrane body by chemically activated groups.
    Type: Application
    Filed: June 17, 2003
    Publication date: November 3, 2005
    Inventors: Wolfgang Demmer, Dietmar Nussbaumer, Hans-Heinrich Horl
  • Publication number: 20050208637
    Abstract: The invention describes a membrane and a method of making and using the same, the membrane being made from a microporous membrane body with an affinity ligand capable of interacting with at least one type of biomolecule found in a fluid, whereby the membrane body may be stored in a dried state yet retain the activity of the affinity ligand.
    Type: Application
    Filed: June 21, 2003
    Publication date: September 22, 2005
    Inventors: Wolfgang Demmer, Dietmar Nussbaumer, Hans-Heinrich Horl
  • Patent number: 6911148
    Abstract: There is disclosed a device for the simultaneous separation of particles and target substances from liquid feeds by adsorption membranes having particle-passing apertures therein.
    Type: Grant
    Filed: September 6, 2000
    Date of Patent: June 28, 2005
    Assignee: Sartorius AG
    Inventors: Wolfgang Demmer, Dietmar Nussbaumer
  • Publication number: 20050115890
    Abstract: The present invention relates to adsorption membranes comprising microporous polymer membranes in which adsorbent particles are incorporated. Furthermore, the present invention relates to a method of producing the inventive adsorption membranes as well as devices which comprise the inventive adsorption membranes.
    Type: Application
    Filed: September 27, 2004
    Publication date: June 2, 2005
    Inventors: Wolfgang Demmer, Stefan Fischer-Fruehholz, Andreas Kocourek, Dietmar Nussbaumer, Eberhard Wuenn
  • Publication number: 20040026322
    Abstract: The present invention relates to a process which can be carried out continuously for the adsorption separation of substances in liquid media, in which process a flat adsorbent is loaded with an adsorbate by contacting the adsorbate-containing medium with the entire adsorbing outer surface of the adsorbent without forced flow through, and to an apparatus for carrying out the inventive process.
    Type: Application
    Filed: June 12, 2003
    Publication date: February 12, 2004
    Applicant: Sartorius AG
    Inventors: Dietmar Nussbaumer, Wolfgang Demmer
  • Patent number: 6562583
    Abstract: A method of conducting a rapid microbiological assay of gases is disclosed that utilizes an improved gelatin membrane filter that is pre-filtered before casting to remove microscopic-sized particles.
    Type: Grant
    Filed: August 9, 2000
    Date of Patent: May 13, 2003
    Assignee: Sartorius AG
    Inventors: Elmar Herbig, Dietmar Nussbaumer, Khuong To Vinh
  • Patent number: 6491869
    Abstract: The abstract discloses a method for preparing supports for the assay of chemical or biological substances, consisting in preparing N different supports, each being homogeneous for a type of reaction, then in mutually combining, according to a predetermined arrangement, all or part of the said homogenous N supports to constitute assay supports having each an ordered set of reaction zones of N different types or less. The invention also concerns the assay supports prepared by this method and their use in processes of immunological hybridisation assays.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: December 10, 2002
    Assignee: Sartorius AG
    Inventors: Wolfgang Demmer, Dietmar Nussbaumer, Khuong To Vinh, Thang Thuong Nguyen, Edwige Bonfils, Daniel Dupret
  • Patent number: 6294090
    Abstract: An adsorptive separation device is disclosed having at least one spiral wound adsorption membrane situated around the periphery of a core mandrel wherein the flow is radial from a feed plenum situated between the core mandrel and the membrane, through the membrane to a permeate plenum located between the membrane and a housing for both the core mandrel and the spiral wound membrane. An array of such separation devices is also disclosed showing connections in parallel, in series, in both parallel and in series and in tandem.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: September 25, 2001
    Assignee: Sartorius AG
    Inventors: Dietmar Nussbaumer, Khoung To Vinh, Abdul Weiss, Wolfgang Demmer, Hans-Heinrich Hörl, Andreas Graus, Günter Pradel
  • Patent number: 6287461
    Abstract: Adsorptive separation is performed on liquid media by directing the media containing a target substance through an adsorber stage A whereby the target substance is adsorbed; in the last phase of loading stage A and prior to breakthrough of the target substance in the stage A permeate, the stage A permeate is directed to a second adsorber stage B. Upon completion of the stage A loading, the target substance from stage A is eluted with buffer solution, which buffer solution is introduced to stage B, and liquid medium is directed to the preloaded stage A, while stage A is eluted so as both recover the target substance and regenerate the adsorptive capacity of stage A.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: September 11, 2001
    Assignee: Sartorius AG
    Inventors: Wolfgang Demmer, Dietmar Nussbaumer, Abdul Weiss
  • Patent number: 6257416
    Abstract: Devices suitable for adsorptive separation, filtration or catalytic conversion of liquid media are disclosed that have ideal dimensions for efficient performance. A method for dimensioning such devices is also disclosed.
    Type: Grant
    Filed: September 20, 1999
    Date of Patent: July 10, 2001
    Assignee: Sartorius AG
    Inventor: Dietmar Nussbaumer
  • Patent number: 6235892
    Abstract: There is disclosed a membrane process for the purification of nucleic acids in aqueous solutions whereby a lasting reduction of endotoxin content is achieved. The process is suitable for small or large volumes and can be carried out quickly and with simple apparatus.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: May 22, 2001
    Assignee: Sartorius AG
    Inventors: Wolfgang Demmer, Dietmar Nussbaumer
  • Patent number: 6017454
    Abstract: A filtration unit for the separation of substances from liquids utilizes a rotatable cylindrical module with a permeable wall disposed within a housing. A filter element which has at least one band of microporous membrane adsorber having a specific adsorption affinity for the substances to be separated is disposed within the cylindrical module so that the membrane absorber is abutted to the cylindrical module. The filter element encircles the feed inlet and can be in the form of an endless loop. A permeate plenum lies between the cylindrical module and the housing. The cylindrical module includes a liquid impermeable end cap which is provided with a coupling member adapted for connection to a drive of variable rotational speed.
    Type: Grant
    Filed: April 14, 1997
    Date of Patent: January 25, 2000
    Assignee: Sartorius AG
    Inventors: Hans-Heinrich Horl, Wolfgang Demmer, Dietmar Nussbaumer