Patents by Inventor Dig Mahat

Dig Mahat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SINGLE-CELL RNA SEQUENCING USING CLICK-CHEMISTRY
    Publication number: 20230121232
    Abstract: The present disclosure relates to a method of sequencing nascent RNA in a cell. In some embodiments, the nascent RNA is conjugated to DNA using copper-catalyzed azide-alkyne cycloaddition (CuAAC). Methods of the present disclosure can be used to generate genomic libraries of a cell and measure gene expression and enhancer and/or super-enhancer activity.
    Type: Application
    Filed: November 2, 2022
    Publication date: April 20, 2023
    Applicant: Massachusetts Institute of Technology
    Inventors: Phillip A. Sharp, Dig Mahat
  • Single-cell RNA sequencing using click-chemistry
    Patent number: 11519027
    Abstract: The present disclosure relates to a method of sequencing nascent RNA in a cell. In some embodiments, the nascent RNA is conjugated to DNA using copper-catalyzed azide-alkyne cycloaddition (CuAAC). Methods of the present disclosure can be used to generate genomic libraries of a cell and measure gene expression and enhancer and/or super-enhancer activity.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: December 6, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Phillip A. Sharp, Dig Mahat
  • SINGLE-CELL RNA SEQUENCING USING CLICK-CHEMISTRY
    Publication number: 20190390266
    Abstract: The present disclosure relates to a method of sequencing nascent RNA in a cell. In some embodiments, the nascent RNA is conjugated to DNA using copper-catalyzed azide-alkyne cycloaddition (CuAAC). Methods of the present disclosure can be used to generate genomic libraries of a cell and measure gene expression and enhancer and/or super-enhancer activity.
    Type: Application
    Filed: March 29, 2019
    Publication date: December 26, 2019
    Applicant: Massachusetts Institute of Technology
    Inventors: Phillip A. Sharp, Dig Mahat