Patents by Inventor Dirk Lindemann

Dirk Lindemann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Foamy viral envelope genes
    Patent number: 8309071
    Abstract: The present invention concerns the technical field of nucleic acids and expression-optimized nucleic acids. The present invention concerns especially nucleic acids comprising a mutated foamy viral envelope gene encoding a foamy viral envelope polypeptide, which comprises a leader peptide (LP), a surface unit (SU) and a transmembrane domain (TM). The present invention also relates to modified polypeptides encoded by these nucleic acids. Furthermore, the present invention regards a method for preparing pseudotyped vector particles as well as a method for treating a genetic disorder comprising administering a nucleic acid or a polypeptide encoded by that nucleic acid.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: November 13, 2012
    Assignee: Vectoria Forschungsforderungs Verein E.V.
    Inventors: Dirk Lindemann, Kristin Stirnnagel, Daniel Lueftenegger
  • FOAMYVIRUS VECTORS AND METHODS OF USE
    Publication number: 20120141440
    Abstract: The disclosure of the present application provides foamyvirus vectors, as well as methods and kits involving the same. In at least one embodiment, a plurality of recombinant vectors comprises an expression sequence encoding at least one component of a foamyvirus particle, wherein at least one codon of the expression sequence is optimized for expression in homo sapiens.
    Type: Application
    Filed: March 26, 2010
    Publication date: June 7, 2012
    Inventors: Axel Rethwilm, Dirk Lindemann, Helmut Hanenberg, Wade D. Clapp
  • FOAMY VIRAL ENVELOPE GENES
    Publication number: 20090325870
    Abstract: The present invention concerns the technical field of nucleic acids and expression-optimized nucleic acids. The present invention concerns especially nucleic acids comprising a mutated foamy viral envelope gene encoding a foamy viral envelope polypeptide, which comprises a leader peptide (LP), a surface unit (SU) and a transmembrane domain (TM). The present invention also relates to modified polypeptides encoded by these nucleic acids. Furthermore, the present invention regards a method for preparing pseudotyped vector particles as well as a method for treating a genetic disorder comprising administering a nucleic acid or a polypeptide encoded by that nucleic acid.
    Type: Application
    Filed: June 27, 2008
    Publication date: December 31, 2009
    Applicant: VECTORIA FORSCHUNGSFOERDERUNGS VEREIN E.V., C/O INSTITUT FUR VIROLOGIE UND IMMUNBIOLOGIE
    Inventors: Dirk Lindemann, Kristin Stirnnagel, Daniel Lueftenegger
  • Nodular cast iron alloy
    Patent number: 6861029
    Abstract: A modified nodular cast iron alloy contains positive additions of boron and silicon in a content of greater than 2.4% by wt.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: March 1, 2005
    Assignee: Georg Fischer Fahrzeugtechnik AG
    Inventors: Werner Menk, Dirk Lindemann, Dirk Richarz
  • Expression of a foamy virus envelope protein
    Patent number: 6703226
    Abstract: The invention concerns constructs for the expression of a protein comprising at least a modified FV envelope protein, the protein so obtained as well as the complementation cell line permitting the production of pseudotyped viral particle. It also concerns pharmaceutical composition comprising said particles and a method for treating a disease.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: March 9, 2004
    Assignee: Transgene S.A.
    Inventors: Dirk Lindemann, Axel Rethwilm
  • Nodular cast iron alloy
    Publication number: 20020195180
    Abstract: A modified nodular cast iron alloy contains positive additions of boron and silicon in a content of greater than 2.4% by wt.
    Type: Application
    Filed: June 20, 2002
    Publication date: December 26, 2002
    Inventors: Werner Menk, Dirk Lindemann, Dirk Richarz
  • Expression of a foamy virus envelope protein
    Patent number: 6277601
    Abstract: The invention concerns constructs for the expression of a protein comprising at least a modified FV envelope protein, the protein so obtained as well as the complementation cell line permitting the production of pseudotyped viral particle. It also concerns pharmaceutical composition comprising said particles and a method for treating a disease.
    Type: Grant
    Filed: December 9, 1999
    Date of Patent: August 21, 2001
    Assignee: Transgene S.A.
    Inventors: Axel Rethwilm, Dirk Lindemann, Arend Jan Winter
  • Expression of a foamy virus envelope protein
    Patent number: 6274722
    Abstract: The invention concerns constructs for the expression of a protein comprising at least a modified FV envelope protein, the protein so obtained as well as the complementation cell line permitting the production of pseudotyped viral particle. It also concerns pharmaceutical composition comprising said particles and a method for treating a disease.
    Type: Grant
    Filed: July 17, 2000
    Date of Patent: August 14, 2001
    Assignee: Transgene S.A.
    Inventors: Dirk Lindemann, Axel Rethwilm
  • Expression of a foamy virus envelope protein
    Patent number: 6150138
    Abstract: The invention concerns constructs for the expression of a protein comprising at least a modified FV envelope protein, the protein so obtained as well as the complementation cell line permitting the production of pseudotyped viral particle. It also concerns pharmaceutical composition comprising said particles and a method for treating a disease.
    Type: Grant
    Filed: May 4, 1999
    Date of Patent: November 21, 2000
    Assignee: Transgene S.A.
    Inventors: Dirk Lindemann, Axel Rethwilm
  • Expression of a foamy virus envelope protein
    Patent number: 6111087
    Abstract: The invention concerns constructs for the expression of a protein comprising at least a modified FV envelope protein, the protein so obtained as well as the complementation cell line permitting the production of pseudotyped viral particle. It also concerns pharmaceutical composition comprising said particles and a method for treating a disease.
    Type: Grant
    Filed: March 13, 1998
    Date of Patent: August 29, 2000
    Assignee: Transgene S.A.
    Inventors: Axel Rethwilm, Dirk Lindemann, Arend Jan Winter
  • Expression of a foamy virus envelope protein
    Patent number: 5929222
    Abstract: The invention concerns constructs for the expression of a protein comprising at least a modified FV envelope protein, the protein so obtained as well as the complementation cell line permitting the production of pseudotyped viral particle. It also concerns pharmaceutical composition comprising said particles and a method for treating a disease.
    Type: Grant
    Filed: March 14, 1997
    Date of Patent: July 27, 1999
    Assignee: Transgene S.A.
    Inventors: Dirk Lindemann, Axel Rethwilm