Abstract: According to some aspects of the invention a method for creation of a wound covering with haemostatic action includes: applying to an open wound a cell structure (grid)-forming water-soluble haemostatic composition designated as a Hemoblok consisting of a polyacrylic matrix as an active ingredient, where the matrix includes one or more polymeric carboxylic acid of a predetermined average molecular weight range, and a bactericidal agent; creating by Hemoblok on a wound surface a structure clot formation with blood plasma proteins, including albumin; creating by Hemoblok on the wound, a covering containing albumin molecules in cells of a polyacrylic structure matrix (grid), which is a primary organizer of sustainable grid structure clot film; further supplying of Hemoblok on an open wound surface to form a multilayered solid grid structure film; terminating of Hemoblok supply on a wound surface with following gradual replacement of a surface structure hemoblok-protein by fibrin.

Abstract: A water-soluble sealant composition and a method for preparing the same which includes: adding soluble silver salt to a polyacrylic acid (PAA) solution; adjusting the pH of the PAA solution to 7-7.4; and heating the PAA solution to 90-125° C. The PAA has a molecular weight between 1000 to 8000. The composition includes a cross-linked poly(acrylic) silver matrix having affinity to proteins. The silver salt can be silver nitrate and/or silver acetate. The matrix may create hydrophilic zones which bind proteins. The composition when in contact with proteins may form hexagonal packing complexes of rod-like poly(acrylic) particles and proteins. It may form a clot made of multi-layered grid structure. In some cases, the complexes create loops that form cells comprising proteins e.g., albumin. The proteins may be of a body fluid such as blood, lymph and combinations thereof. The composition may be applied for a medical condition such as hemorrhage and lymphorrhea.

Abstract: The present invention relates to the field of medicine, generally to the field of surgical and emergency medical wound covering means on the base of haemostatic composition designated as Hemoblok. The invention proposes a new method of usage of these haemostatic compositions to activate the formation of artificial clots that can adhere to wounded tissue for the suppression of fluid loss and for the protection of viable tissue.

Abstract: A prosthetic material having non-thrombogenic properties for the vascular system of the body. The material has a base layer made from a suitable material, and a thin substantially amorphous or quasi-amorphous and preferably non-continuous layer made from a suitable metal covering at least part of the base layer. The metal layer is made from a suitable metal such as to provide a substantially non-positive electrode potential with respect to a bloodstream in contact with said metal layer. The metal layer forms the bloodstream facing surface of the prosthetic material, which may be adapted to provide patches, prosthetics and other components suitable for the vascular system.