Patents by Inventor Dmitry M. Guschin

Dmitry M. Guschin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted genomic modification with partially single-stranded donor molecules
    Patent number: 9970028
    Abstract: Disclosed herein are donor molecules comprising single-stranded complementary regions flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: May 15, 2018
    Assignee: Sangamo Therapeutics, Inc.
    Inventors: Gregory J. Cost, Dmitry M. Guschin, Fyodor Urnov
  • TARGETED GENOMIC MODIFICATION WITH PARTIALLY SINGLE-STRANDED DONOR MOLECULES
    Publication number: 20160145644
    Abstract: Disclosed herein are donor molecules comprising single-stranded complementary regions flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.
    Type: Application
    Filed: January 7, 2016
    Publication date: May 26, 2016
    Inventors: Gregory J. Cost, Dmitry M. Guschin, Fyodor Urnov
  • Targeted genomic modification with partially single-stranded donor molecules
    Patent number: 9255259
    Abstract: Disclosed herein are donor molecules comprising single-stranded complementary regions flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.
    Type: Grant
    Filed: February 9, 2011
    Date of Patent: February 9, 2016
    Assignee: Sangamo BioSciences, Inc.
    Inventors: Gregory J. Cost, Dmitry M. Guschin, Fyodor Urnov
  • Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) gene
    Patent number: 9161995
    Abstract: Nucleases and methods of using these nucleases for alteration of a CFTR gene and generation of cells and animal models.
    Type: Grant
    Filed: July 25, 2012
    Date of Patent: October 20, 2015
    Assignee: Sangamo BioSciences, Inc.
    Inventors: Dmitry M. Guschin, Michael C. Holmes, David Paschon, Phillip Tam
  • Targeted genomic modification with partially single-stranded donor molecules
    Patent number: 9005973
    Abstract: Disclosed herein are donor molecules comprising single-stranded complementary regions flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: April 14, 2015
    Assignee: Sangamo BioSciences, Inc.
    Inventors: Gregory J. Cost, Dmitry M. Guschin, Fyodor Urnov
  • METHODS AND COMPOSITIONS FOR ALTERATION OF A CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) GENE
    Publication number: 20140205579
    Abstract: Nucleases and methods of using these nucleases for alteration of a CFTR gene and generation of cells and animal models.
    Type: Application
    Filed: March 25, 2014
    Publication date: July 24, 2014
    Applicants: Board of Regents of the University of Texas System, Sangamo BioSciences, Inc.
    Inventors: Brian R. Davis, Dmitry M. Guschin, Michael C. Holmes, David Paschon, Phillip Tam
  • METHODS AND COMPOSITIONS FOR ALTERATION OF A CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) GENE
    Publication number: 20130145485
    Abstract: Nucleases and methods of using these nucleases for alteration of a CFTR gene and generation of cells and animal models.
    Type: Application
    Filed: July 25, 2012
    Publication date: June 6, 2013
    Inventors: Brian R. Davis, Dmitry M. Guschin, Michael C. Holmes, David Paschon, Philip Tam
  • Targeted genomic modification with partially single-stranded donor molecules
    Publication number: 20110287545
    Abstract: Disclosed herein are donor molecules comprising single-stranded complementary regions flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.
    Type: Application
    Filed: July 8, 2011
    Publication date: November 24, 2011
    Inventors: Gregory J. Cost, Dmitry M. Guschin, Fyodor Urnov
  • Targeted genomic modification with partially single-stranded donor molecules
    Publication number: 20110207221
    Abstract: Disclosed herein are donor molecules comprising single-stranded complementary regions flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.
    Type: Application
    Filed: February 9, 2011
    Publication date: August 25, 2011
    Inventors: Gregory J. Cost, Dmitry M. Guschin, Fyodor Urnov