Patents by Inventor Do-Sun LIM

Do-Sun LIM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STEM CELL-DERIVED MATURE CARDIOMYOCYTES AND CARDIOVASCULAR DISEASE MODEL USING SAME
    Publication number: 20240084259
    Abstract: The present invention relates to stem cell-derived mature cardiomyocytes and a cardiovascular disease model using same and, more specifically, to differentiation into mature ventricular cardiomyocytes by culturing stem cells in a medium containing FGF4 and ascorbic acid, and use of the differentiated mature ventricular cardiomyocytes as a cardiovascular disease cell model. The mature ventricular cardiomyocytes, obtained by culturing stem cells in a medium containing FGF4 and ascorbic acid and inducing the differentiation thereof, and cardiovascular disease cell model using same according to the present invention are very useful for screening for cardiovascular disease therapeutic agents and evaluation of the toxicity of new drugs.
    Type: Application
    Filed: November 13, 2019
    Publication date: March 14, 2024
    Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Do-Sun LIM, Seung Cheol CHOI, Hyung Joon JOO, Jong-Ho KIM, Chi-Yeon PARK, Yongdoo PARK