Patents by Inventor Domenico Tortorella

Domenico Tortorella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230391856
    Abstract: Provided herein are antibodies that bind to SARS-CoV-2 spike protein or a fragment thereof (e.g., receptor binding domain (RBD)), host cells for producing such antibodies, and kits comprising such antibodies. Also provided herein are compositions comprising antibodies that bind to SARS-CoV-2 spike protein or a fragment thereof (e.g., receptor binding domain) and methods of using such antibodies to diagnose, prevent or treat a SARS-CoV-2 infection, or COVID-19.
    Type: Application
    Filed: October 22, 2021
    Publication date: December 7, 2023
    Applicant: Icahn School of Medicine at Mount Sinai
    Inventors: Thomas Moran, Thomas Kraus, Domenico Tortorella, J. Andrew Duty
  • Publication number: 20220356228
    Abstract: Provided herein are monoclonal antibodies and antigen-binding fragments thereof that bind to the John Cunningham virus. Also provided are pharmaceutical compositions comprising the monoclonal antibodies and antigen-binding fragments thereof, as well as methods of using such monoclonal antibodies and antigen-binding fragments thereof, including methods for the treatment and/or prevention of JCV infections and/or progressive multifocal leukoencephalopathy.
    Type: Application
    Filed: June 19, 2020
    Publication date: November 10, 2022
    Applicant: Icahn School of Medicine at Mount Sinai
    Inventors: Thomas Moran, Thomas Kraus, J. Andrew Duty, Domenico Tortorella
  • Patent number: 11185582
    Abstract: The present disclosure relates to anti-human cytomegalovirus (anti-HCMV) antibodies and vaccines as well as diagnostic and therapeutic methods of use.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: November 30, 2021
    Assignee: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Thomas Gardner, Thomas Moran, Domenico Tortorella
  • Publication number: 20200330588
    Abstract: The present disclosure relates to anti-human cytomegalovirus (anti-HCMV) antibodies and vaccines as well as diagnostic and therapeutic methods of use.
    Type: Application
    Filed: May 9, 2017
    Publication date: October 22, 2020
    Inventors: Thomas Gardner, Thomas Moran, Domenico Tortorella
  • Patent number: 5340451
    Abstract: A process is disclosed for producing a metal-organic polymer combination by contacting the polymer with a plasma followed by an aqueous solution of a metal salt. In one embodiment a water or nitrous oxide plasma is used to treat a polyimide or a fluorinated polymer. The polymer is combined with a metal cation, the metal being a catalyst for a conventional electroless coating after which it is contacted with an electroless metal plating bath for the formation of electrical circuits and especially for plating high aspect ratio vias in microcircuits. Unlike the conventional electroless process, the cationic catalytic metal is not reduced to a zero valent metal catalyst prior to the application of the electroless metal coating solution.The process also improves the wettability of the polymer, especially the fluorinated polymer and is especially useful in improving the wettability of high aspect ratio vias.
    Type: Grant
    Filed: May 13, 1993
    Date of Patent: August 23, 1994
    Assignee: International Business Machines Corporation
    Inventors: Leena P. Buchwalter, Stephen L. Buchwalter, Charles R. Davis, Ronald D. Goldblatt, John E. Heidenreich, III, Sharon L. Nunes, Jae M. Park, Richard R. Thomas, Domenico Tortorella, Luis M. Ferreiro, deceased
  • Patent number: 5178914
    Abstract: A method for seeding the surface of a polyimide film which has been generated from a precursor polyamic acid film comprising the steps of: generating a film of polyamic acid on a substance (which may be done by conventional spin coating or by other solution coating techniques well known in the art); then either exposing the polyamic acid film to a solution containing palladium cations; heat-treating the palladium-treated film in a time/temperature schedule that causes imidization of the polymer to occur; exposing the seeded film to an electroless plating bath which causes the deposition of blanket metal film on the surface of the polymer film; or curing the film to the polyimide form; mechanically abrading the film surface, exposing the film to a solution containing palladium cations; exposing the seeded film to an electroless plating bath which causes the deposition of blanket metal film on the surface of the polymer film.
    Type: Grant
    Filed: October 30, 1990
    Date of Patent: January 12, 1993
    Assignee: International Business Machines Corp.
    Inventors: Ronald D. Goldblatt, Caroline A. Kovac, Domenico Tortorella